Results 221 to 230 of about 2,253,320 (251)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Important Role of Renin-Angiotensin System and Vasopressin System in Cardiovascular, Metabolic and Psychogenic Disorders in Pregnancy and Early Postnatal Life: A Narrative Review. [PDF]

Int J Mol Sci
Szczepańska-Sadowska E.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Non-Work-Matched HIIT and MIIT Partially Restore Exerkine-Related and Mitochondrial Gene Expression in Diabetic Rat Skeletal Muscle. [PDF]

Biomolecules
Rezae S, Mehr PA, Pournemati P, Laher I, Eken Ö, Aldhahi MI.   +5 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Hepatobiliary involvement in Kawasaki disease: from cholestatic hepatitis to the hepatic vascular-biliary unit hypothesis-a state-of-the-art review. [PDF]

Front Immunol
Zhong YX, Zheng Q, Yang FY.
europepmc   +1 more source

High-intensity interval training attenuates urothelial nerve growth factor and angiotensin axis in hypertensive urinary bladder. [PDF]

Hypertens Res
Batista VRG, Tavares MEA, Sousa Neto IV, Rubira RJG, Oliveira TA, Veras ASC, Chaves-Neto AH, Souza FLA, Pacagnelli FL, Fernandes VSL, Teixeira GR.   +10 more
europepmc   +1 more source

Differential Modulation of Spinal Angiotensin-Converting Enzymes Plays a Critical Role in the Development of Trigeminal Neuropathic Pain. [PDF]

Pharmaceuticals (Basel)
Son JY, Kim YM, Kang SH, Ju JS, Ahn DK.
europepmc   +1 more source

Vascular Sphingosine Kinase 1 Regulates Angiotensin II-Induced Hypertension. [PDF]

Hypertension
Jozefczuk E, Szczepaniak P, Mikolajczyk TP, Nosalski R, Dziedzic M, Urbanski K, Wojciechowska E, Filip G, Stefanska M, Blyszczuk P, Guzik TJ, Siedlinski M.   +11 more
europepmc   +1 more source

Type I Interferon and Still Disease. [PDF]

Arthritis Rheumatol
Cron RQ, Onel KB.
europepmc   +1 more source