Kinome profiling reveals pathogenic variant specific protein signalling networks in MEN2 children with Medullary Thyroid Cancer. [PDF]
Rix B+12 more
europepmc +1 more source
Regulation of T-Cell Antigen Receptor Signalling by Syk Tyrosine Protein Kinase
Sylvain Latour+2 more
openalex +1 more source
Signaling Complexes and Protein-Protein Interactions Involved in the Activation of the Ras and Phosphatidylinositol 3-Kinase Pathways by the c-Ret Receptor Tyrosine Kinase [PDF]
Valérie Besset+2 more
openalex +1 more source
Peripheral nerve injury necessitates alternatives to autografts. This study combines magnetic nanoparticles, oriented PCL fibers, and Ppy to create a conductive, magnetically active scaffold. In vitro and in vivo experiments demonstrated enhanced downstream pathways of calcium signaling, as revealed by transcriptome analysis.
Zheyuan Fan+4 more
wiley +1 more source
The Src family kinase inhibitor drug Dasatinib and glucocorticoids display synergistic activity against tongue squamous cell carcinoma and reduce MET kinase activity. [PDF]
Hmedat ANA+4 more
europepmc +1 more source
Vav3 Mediates Receptor Protein Tyrosine Kinase Signaling, Regulates GTPase Activity, Modulates Cell Morphology, and Induces Cell Transformation [PDF]
Liyu Zeng+7 more
openalex +1 more source
Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai+5 more
wiley +1 more source
Repurposing of the Syk inhibitor fostamatinib using a machine learning algorithm. [PDF]
Choi Y+8 more
europepmc +1 more source
Co-ordination of the expression of the protein tyrosine kinase p56lck with the pre-T cell receptor during thymocyte development [PDF]
Jennifer Buckland+3 more
openalex +1 more source