Results 261 to 270 of about 514,942 (384)

Regulation of T-Cell Antigen Receptor Signalling by Syk Tyrosine Protein Kinase

, 1997
Sylvain Latour, Marielle Fournel, André Veillette   +2 more
openalex   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

JAK-STAT Signaling in Autoimmunity and Cancer. [PDF]

Immunotargets Ther
Parveen S, Fatma M, Mir SS, Dermime S, Uddin S.   +4 more
europepmc   +1 more source

Catalytic activity of the mouse guanine nucleotide exchanger mSOS is activated by Fyn tyrosine protein kinase and the T-cell antigen receptor in T cells.

, 1996
Bin Li, Marianne Subleski, Noemi Fusaki, Tadashi Yamamoto, T D Copeland, G L Princler, Hsiang‐Fu Kung, Tohru Kamata   +7 more
openalex   +1 more source

GIPC and GAIP Form a Complex with TrkA: A Putative Link between G Protein and Receptor Tyrosine Kinase Pathways [PDF]

, 2001
Xiaojing Lou, Hiroko Yano, Francis Lee, Moses V. Chao, Marilyn G. Farquhar   +4 more
openalex   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

Type One Protein Phosphatase 4aD Negatively Regulates Cotton (<i>Gossypium hirsutum</i>) Salt Tolerance by Inhibiting the Phosphorylation of Kinases That Respond to Abscisic Acid. [PDF]

Int J Mol Sci
Cao P, Zhao M, Liu J, Du M, Tian X, Li F, Li Z.   +6 more
europepmc   +1 more source

PDGF Receptor Protein Tyrosine Kinase Expression in the Balloon-Injured Rat Carotid Artery

, 1997
Robert L. Panek, Tawny K. Dahring, Bronia Olszewski, Joan A. Keiser   +3 more
openalex   +1 more source

Identification and Drug Screening of Single Cells from Human Tumors on Semiconductor Chip for Cancer Precision Medicine

Advanced Science, EarlyView.
The study innovatively integrates single‐cell electric impedance identification and drug screening on a semiconductor chip, addressing tumor heterogeneity limitations. The system achieves label‐free cancer cell recognition while concurrently evaluating drug efficacy on cancer cells and toxicity on noncancerous cells.
Wenhao Hui, Ka‐Meng Lei, Yingying Liu, Xinru Huang, Yunlong Zhong, Xiaojun Chen, Mingji Wei, Jie Yan, Ren Shen, Pui‐In Mak, Rui P. Martins, Shuhong Yi, Ping Wang, Yanwei Jia   +13 more
wiley   +1 more source

The p130Cas-Crk/CrkL Axis: A Therapeutic Target for Invasive Cancers Unveiled by Collaboration Among p130Cas, Crk, and CrkL. [PDF]

Int J Mol Sci
Farhadi P, Park T.
europepmc   +1 more source