Results 121 to 130 of about 248,286 (331)

Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron‐deficient cores. Nevertheless, they are now extending their application to biology.
Jean‐Elie Zheng   +2 more
wiley   +1 more source

Assessment of Effects of α2-Adrenoceptor Agonists and Antagonists in Dorsal Hippocampus on Muscimol State-dependent Memory

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2014
Background and Objectives: Adrenergic and GABAergic systems of the brain play an important role in memory and learning. According to results of studies, morphine, histamine, and lithium induce state-dependent learning.
Morteza Piri   +2 more
doaj  

Autoantibodies to beta-adrenergic and muscarinic cholinergic receptors in Myalgic Encephalomyelitis (ME) patients – A validation study in plasma and cerebrospinal fluid from two Swedish cohorts

open access: yesBrain, Behavior, & Immunity - Health, 2020
Myalgic encephalomyelitis (ME) also known as ME/CFS (Chronic Fatigue Syndrome) or ME/SEID (Systemic Exertion Intolerance Disorder), is a disabling and often long-lasting disease that can drastically impair quality of life and physical/social functioning ...
Annie Bynke   +5 more
doaj  

L-Tetrahydropalamatine: A Potential New Medication for the Treatment of Cocaine Addiction [PDF]

open access: yes, 2012
Levo-tetrahydropalmatine (l-THP) is an active constituent of herbal preparations containing plant species of the genera Stephania and Corydalis and has been approved and used in China for a number of clinical indications under the drug name Rotundine ...
Mantsch, John R., Wang​, Jia Bei
core   +1 more source

The Chicken Egg Genotoxicity Assay (CEGA): Assessing Target Tissue Exposure and Metabolism in the Embryo‐Fetal Chicken Livers

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The Chicken Egg Genotoxicity Assay (CEGA) is an avian egg‐based model that utilizes the livers of developing chicken embryo‐fetuses to assess the ability of chemicals to produce direct DNA damage. The main goal of the study was to evaluate target tissue exposure and metabolism in the CEGA to assess its suitability as a biologically relevant ...
Yax Thakkar   +4 more
wiley   +1 more source

Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management [PDF]

open access: yes, 2019
Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the
Bratu, Ovidiu G   +6 more
core   +1 more source

Ca2+ signaling in porcine myometrial cells: Ca2+ channels, intracellular Ca2+ stores and guanine nucleotide-binding protein-coupled receptors [PDF]

open access: yes, 1995
Fura-2 spectrofluorometry and imaging, and whole-cell patch-clamp techniques were used to characterize Ca[superscript]2+ channels and intracellular Ca[superscript]2+ stores for exploring signal transduction of the oxytocin receptor and the [alpha ...
ZhuGe, Ronghua
core   +2 more sources

Glutamate Receptor Modulation Is Restricted to Synaptic Microdomains

open access: yesCell Reports, 2015
A diverse array of neuromodulators governs cellular function in the prefrontal cortex (PFC) via the activation of G-protein-coupled receptors (GPCRs). However, these functionally diverse signals are carried and amplified by a relatively small assortment ...
Gyorgy Lur, Michael J. Higley
doaj   +1 more source

Things We Do for No Reason: Failing to consider primary aldosteronism in the initial evaluation of hypertension, hypertensive urgency, and hypertensive emergency

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Hypertension is frequently treated as essential hypertension. However, secondary causes of hypertension should be considered, because distinct treatments are used for different causes of hypertension. Primary aldosteronism is considered a candidate for the most common cause of secondary hypertension.
Michael C. Shih   +4 more
wiley   +1 more source

Estrogen-Related Receptors Mediate the Adaptive Response of Brown Adipose Tissue to Adrenergic Stimulation

open access: yesiScience, 2018
Summary: Adrenergic stimulation of brown adipose tissue (BAT) induces acute and long-term responses. The acute adrenergic response activates thermogenesis by uncoupling oxidative phosphorylation and enabling increased substrate oxidation.
Erin L. Brown   +9 more
doaj  

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