Results 21 to 30 of about 93,900,112 (260)
Brain, Behavior, & Immunity - Health, 2020 Myalgic encephalomyelitis (ME) also known as ME/CFS (Chronic Fatigue Syndrome) or ME/SEID (Systemic Exertion Intolerance Disorder), is a disabling and often long-lasting disease that can drastically impair quality of life and physical/social functioning ...
Annie Bynke +5 more
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MODERN POSSIBILITIES OF MEDICAL TREATMENT OF OVERACTIVE BLADDER IN WOMEN
Медицинский совет, 2017 Overactive bladder (OAB) is a serious urination disorder which affects at least 17% of the population above 40 years old, of which 56% are women and 44% are men. M-cholinoblockers are the first line therapy and the main treatment for OAB.
I. A. Apolikhina +3 more
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Journal of Lipid Research, 1988 The beta-adrenergic receptors of isolated human fat cells were identified using a new hydrophilic beta-adrenergic radioligand (+/-)[3H]CGP-12177. The results were compared with those from [3H]dihydroalprenolol binding to fat cells and membranes.
D Lacasa +4 more
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.BETA.3-Adrenergic receptor agonists. Past, present and future.
Folia Pharmacologica Japonica, 2001 beta 3-Adrenergic receptors (beta 3-AR) play an important role in the thermogenesis in brown adipose tissue and lipolysis in white adipose tissue. beta 3-AR agonists developed in the early stages produced marked weight reduction and an anti-diabetic effect in rats and mice, but did not in humans, because of the difference in the chemical structure of ...
Y, Takakura, T, Yoshida
openaire +4 more sources
Everything You Always Wanted to Know about β3-AR * (* But Were Afraid to Ask)
Cells, 2019 The beta-3 adrenergic receptor (β3-AR) is by far the least studied isotype of the beta-adrenergic sub-family. Despite its study being long hampered by the lack of suitable animal and cellular models and inter-species differences, a substantial body ...
Giorgia Schena, Michael J. Caplan
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Cardiac salvage by tweaking with beta-3-adrenergic receptors [PDF]
Cardiovascular Research, 2016 Overstimulation of the orthosympathetic system leads to cardiovascular cell and tissue damage through prolonged activation of β-1-2 adrenergic receptors (BARs). The more recent identification of the third isotype of BAR (B3AR) in cardiac myocytes and endothelial cells with a distinctive coupling and effect on cardiac function and remodelling introduced
openaire +2 more sources
Fat cell adrenergic receptors and the control of white and brown fat cell function
Journal of Lipid Research, 1993 Five adrenoceptor subtypes are involved in the adrenergic regulation of white and brown fat cell function. The effects on cAMP production and cAMP-related cellular responses are mediated through the control of adenylyl cyclase activity by the stimulatory
M Lafontan, M Berlan
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3-Iodothyronamine Affects Thermogenic Substrates’ Mobilization in Brown Adipocytes
Biology, 2020 We investigated the effect of 3-iodothyronamine (T1AM) on thermogenic substrates in brown adipocytes (BAs). BAs isolated from the stromal fraction of rat brown adipose tissue were exposed to an adipogenic medium containing insulin in the absence (M) or ...
Manuela Gencarelli +6 more
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Results in Chemistry, 2023 Derivatives of dihydropyridines are promising agents for research, as they have high biological activity. Their low toxicity and polytargeted properties make it possible to create new derivatives and identify new biological activity. As part of this work,
Arkadiy Bryzgalov +3 more
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Induction and properties of beta-adrenergic receptors during erythroid differentiation of Friend leukemic cells [PDF]
, 1980 beta-Adrenergic receptors on Friend erythroleukemic cells were identified by the use of 125I-labeled hydroxybenzylpindolol, a potent beta-adrenergic antagonist. Binding of this ligand was saturable and stereospecific.
R. Pochet +7 more
core +1 more source