Research Progress of Androgen/Androgen Receptor Signaling Pathway in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is a kind of primary liver cancer with a high mortality rate. In China, the incidence ratio in males to females with HCC is 2:1–5:1.
WANG Ruihua +4 more
doaj +1 more source
Androgen and Estrogen Receptor Expression in Different Types of Perianal Gland Tumors in Male Dogs
Perianal gland tumors are modified sebaceous glands present in the skin of the perianal region in the dog. Hormonal stimulation may induce hyperplasia of the perianal glands or their neoplastic progression. The presence of androgen (AR) and estrogen (ER)
Adam Brodzki +6 more
doaj +1 more source
Effect of antiandrogen flutamide on measures of hepatic regeneration in rats [PDF]
Male rat liver undergoes a process of demasculinization during hepatic regeneration following partial hepatectomy. The possibility that antiandrogens might potentiate this demasculinization process and in so doing augment the hepatic regenerative ...
A Francavilla +36 more
core +1 more source
Membrane Androgen Receptors Unrelated to Nuclear Steroid Receptors.
Rapid (nongenomic) membrane-initiated androgen actions have been described in nuclear androgen receptor-null cells. Four distinct proteins have been proposed as membrane androgen receptors (mARs) or sensors.
P. Thomas
semanticscholar +1 more source
Background Steroid action is mediated, in addition to classical intracellular receptors, by recently identified membrane sites, that generate rapid non-genomic effects.
Theodoropoulos Panayiotis A +8 more
doaj +1 more source
Transcriptional and posttranscriptional regulation of human androgen receptor expression by androgen. [PDF]
Autoregulation is a control mechanism common to several proteins of the steroid/thyroid hormone receptor superfamily. In this work the effect of androgens and antiandrogens on the expression of the human androgen receptor (hAR) in prostate and breast ...
Blasschke, Dorothea +4 more
core +1 more source
Gonadal steroids exert important feedback influences on hypothalamic neurones involved in regulating reproductive behaviour and pituitary hormone secretion.
A. Herbison
semanticscholar +1 more source
Partial Androgen Insensitivity Syndrome Presenting with Gynecomastia [PDF]
Gynecomastia is a benign enlargement of the male breast caused by the proliferation of glandular breast tissue. Determining the various causes of gynecomastia such as physiological causes, drugs, systemic diseases, and endocrine disorders is important ...
Sung Won Lee +10 more
doaj +1 more source
Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]
Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H. +4 more
core +2 more sources
Immunohistochemical expression of androgen receptors in prostate carcinoma and benign prostatic hyperplasia [PDF]
Background/Aim. Prostate carcinoma (PCa) and its parent organ are influenced by hormones, which is used for therapeutic purposes. Through androgen receptors (AR) androgens influence cell growth and function, proliferation, differentiation, apoptosis ...
Trivunić-Dajko Sandra +4 more
doaj +1 more source

