Results 91 to 100 of about 97,708 (240)

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

open access: yesAggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai   +6 more
wiley   +1 more source

Predicting progression of aortic stenosis by measuring serum calcification propensity

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1297-1302, December 2022., 2022
Abstract Background The aim of this prospective, double‐blinded study in patients with aortic sclerosis was to determine whether a new calcification propensity measure in the serum could predict disease progression. Methods We included 129 consecutive patients with aortic sclerosis as assessed during a routine clinical echocardiographic exam. Clinical,
Reto Kurmann   +4 more
wiley   +1 more source

«New» molecules composed of rational combinations of antihypertensive drugs: issues of choice [PDF]

open access: yesСистемные гипертензии, 2015
The article discusses the factors that determine the choice of antihypertensive drugs, especially blockers of receptors of angiotensin and thiazide diuretics. The data about the peculiarities of azilsartan medoxomil, it differs from other sartans.
O A Kislyak, Yu B Chervyakova
doaj  

Response of Renal Podocytes to Excessive Hydrostatic Pressure: a Pathophysiologic Cascade in a Malignant Hypertension Model

open access: yesKidney & Blood Pressure Research, 2017
Background/Aims: Renal injuries induced by increased intra-glomerular pressure coincide with podocyte detachment from the glomerular basement membrane (GBM).
Ramzia Abu Hamad   +6 more
doaj   +1 more source

Structural analysis of SARS-CoV-2 and prediction of the human interactome [PDF]

open access: yesarXiv, 2020
Specific elements of viral genomes regulate interactions within host cells. Here, we calculated the secondary structure content of >2500 coronaviruses and computed >100000 human protein interactions with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
arxiv  

Prevalence, clinical characteristics, and predictors of sleep disordered breathing in hospitalized heart failure patients

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1311-1318, December 2022., 2022
Abstract Background Heart failure (HF) is often comorbid with sleep disordered breathing (SDB). This prospective study investigated the prevalence, clinical characteristics, and predictors of SDB in hospitalized HF patients. Methods Sleep studies were performed on hospitalized HF patients from January 2015 to February 2019.
Boping Huang   +8 more
wiley   +1 more source

The angiotensin II receptors type 1 and 2 modulate astrocytes and their crosstalk with microglia and neurons in an in vitro model of ischemic stroke

open access: yesBMC Neuroscience
Background Astrocytes are the most abundant cell type of the central nervous system and are fundamentally involved in homeostasis, neuroprotection, and synaptic plasticity.
Daniel Navin Olschewski   +12 more
doaj   +1 more source

Angiotensins and Huntington’s Disease: A Study on Immortalized Progenitor Striatal Cell Lines

open access: yesFrontiers in Endocrinology, 2017
Neurons from mouse models of Huntington’s disease (HD) exhibit altered electrophysiological properties, potentially contributing to neuronal dysfunction and neurodegeneration.
Walmor C. De Mello   +2 more
doaj   +1 more source

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