Results 131 to 140 of about 97,708 (240)

Data supporting that adipose-derived mesenchymal stem/stromal cells express angiotensin II receptors in situ and in vitro

Data in Brief, 2018
This article contains results of analyses of angiotensin II receptors expression in human adipose tissue and stem/stromal cells isolated from adipose tissue.
Liudmila V. Ageeva, Veronika Y. Sysoeva, Pyotr A. Tyurin-Kuzmin, George V. Sharonov, Daniyar T. Dyikanov, Dmitry V. Stambolsky, Natalia I. Kalinina   +6 more
doaj  

Real Time Hemodynamic Monitoring During M‐TEER Using Electrical Cardiometry

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Mitral regurgitation is a common valvular dysfunction causing patient morbidity and mortality. Mitral transcatheter edge‐to‐edge repair (M‐TEER) allows grasping of valvular leaflets and approximation via a small implant, thus reducing mitral regurgitation (MR).
Andreas Goldschmied, Manuel Sigle, Ioannis Toskas, Monika Zdanyte, Mareike Bladt, Meinrad Gawaz, Tobias Geisler   +6 more
wiley   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan C. Shetty, Sujina S. S, Rukmini Mysore Srikantiah, Sowndarya Kollampare   +5 more
wiley   +1 more source

Multicenter trial of olmesartan. Main results

Терапевтический архив, 2011
Development and introduction into practice of medicines reducing activity of the renin-angiotensin-aldosteron system the key element of which is angiotensin II (ATII) resulted in a significant improvement of efficacy of cardiovascular diseases treatment.
Fail' Taipovich Ageev, Ol'ga Nikolaevna Svirida, F T Ageev, O N Svirida   +3 more
doaj  

Rapid response to fast viral evolution using AlphaFold 3-assisted topological deep learning [PDF]

arXiv
The fast evolution of SARS-CoV-2 and other infectious viruses poses a grand challenge to the rapid response in terms of viral tracking, diagnostics, and design and manufacture of monoclonal antibodies (mAbs) and vaccines, which are both time-consuming and costly. This underscores the need for efficient computational approaches.
arxiv  

A Phase 1C, Open Label, Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of DM199 Administered Intravenously with a Polyvinyl Chloride Bag in Adult Healthy Subjects and Adults Recently Taking Angiotensin‐Converting Enzyme Inhibitors

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This small phase 1C, open‐label, single ascending dose study evaluated the safety, tolerability, and pharmacokinetics (PKs) of DM199, a recombinant form of human tissue kallikrein‐1 (KLK1). A small sample size of both healthy subjects and hypertensive adults recently taking angiotensin‐converting enzyme inhibitors was studied. KLK1 has a known
Michael Giuffre, Annette D. Lista, Nick Paulson, Lorianne Masuoka   +3 more
wiley   +1 more source

GPCR dimerization: Drug discovery aspects and targets in renin-angiotensin systems. [PDF]

FASEB Bioadv
Faisal T, Hussain T.
europepmc   +1 more source

A perspective on small molecules targeting the renin-angiotensin-aldosterone system and their utility in cardiovascular diseases: exploring the structural insights for rational drug discovery and development. [PDF]

RSC Med Chem
Bansal N, Kathuria D, Babu AM, Dhiman S, Lakhanpal S, Prasad KN, Kumar R, Tyagi Y, Kumar B, Singh MP, Gaidhane AM.   +10 more
europepmc   +1 more source

Drug‐Event Pairs as Indicators for the Detection of Adverse Drug Reactions during Hospitalization in Routinely Collected Electronic Data Sources

Clinical Pharmacology &Therapeutics, EarlyView.
Adverse drug reactions (ADRs) are a common cause of morbidity and mortality in hospitalized patients. Identification of ADRs in clinical practice, surveillance and research is essential to prevent further harm. The aim of this study was to assess the likelihood of drugs contributing to clinically important inpatient adverse events, in order to provide ...
Anna Maria Wermund, Annette Haerdtlein, Wolfgang Fehrmann, Clara Weglage, Tobias Dreischulte, Ulrich Jaehde   +5 more
wiley   +1 more source

Modulation of RAAS receptors and miRNAs in COVID-19: implications for disease severity, immune response, and potential therapeutic targets. [PDF]

BMC Infect Dis
Barreto Fernandes TF, Pilotto JH, Cezar PA, Côrtes FH, Morgado MG, Giacoia-Gripp CBW, De Sá NBR, Da Silva Cazote A, Neves AF, Quintana MSB, Diniz Ribeiro MP, Cardoso SW, Veloso VG, Grinsztejn B, De Almeida DV.   +14 more
europepmc   +1 more source