Results 201 to 210 of about 1,151,937 (336)

A paradigm shift in simulating affinity maturation to elicit broadly neutralizing antibodies. [PDF]

Front Immunol
Nakarin F, Sprenger KG.
europepmc   +1 more source

Optimized Cell‐Based Platform for Platelet‐Free Detection of Heparin‐Induced Thrombocytopenia Antibodies

Advanced Biology, EarlyView.
This study optimized a cell‐based ELISA for HIT antibody detection using PF4‐coated breast cancer cells (MDA‐MB‐231). Enhanced binding was observed at 50 mM NaCl and 4% paraformaldehyde fixation. Live MDA‐MB‐231 and HCT‐116 cells demontrated superior sensitivity and specificity, providing a promising platelet‐free alternative for clinical HIT diagnosis.
Li‐Yu Chen, Uwe Schirmer, Peter F. Zipfel, Doris Heinrich, Thi‐Huong Nguyen   +4 more
wiley   +1 more source

Elementary immunology [PDF]

, 2017
Gogolák, Péter, Koncz, Gábor
core  

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Constructing the cure: engineering the next wave of antibody and cellular immune therapies. [PDF]

J Immunother Cancer
Bailey SR, Bartee E, Daniels KG, Heery CR, Kaumaya P, Lesinski GB, Lowinger TB, Nelson MH, Rubinstein MP, Wittling MC, Paulos CM, Posey AD.   +11 more
europepmc   +1 more source

T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells

Cancer immunology research, 2016
Eugenia Zah, Meng-Yin Lin, Anne Silva-Benedict, M. Jensen, Y. Chen   +4 more
semanticscholar   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

Key Trends and Insights in Smart Polymeric Skin Wearable Patches

Advanced Engineering Materials, EarlyView.
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez, Rajat Rai, Miryam Criado‐Gonzalez   +2 more
wiley   +1 more source

B cell development: transcriptional regulation and immunological mechanisms in homeostasis. [PDF]

Front Immunol
Gómez-Manríquez J, Hernández-Bello J, Muñoz-Valle JF, Sifuentes-Franco S, Graciano-Machuca O, Morales-Núñez JJ.   +5 more
europepmc   +1 more source

The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor.

Blood, 2010
M. Hudecek, Thomas M. Schmitt, S. Baskar, M. Lupo-Stanghellini, T. Nishida, Tori N. Yamamoto, M. Bleakley, C. Turtle, W. Chang, H. Greisman, B. Wood, D. Maloney, M. Jensen, C. Rader, S. Riddell   +14 more
semanticscholar   +1 more source