Results 101 to 110 of about 21,215 (175)

A critical appraisal of the safety of bedinvetmab (Beransa), a canine antinerve growth factor monoclonal antibody

open access: yesAustralian Veterinary Journal, Volume 104, Issue 8, Page 549-556, August 2026.
Clinical scenario Canine osteoarthritis (OA) is a degenerative joint disease and is one of the most common chronic conditions in dogs and other species. The management of OA remains a longstanding focus in veterinary medicine. Traditionally, nonsteroidal anti‐inflammatory drugs (NSAIDs) have been the first‐line treatment option for canine OA. Recently,
X Yang, P Macarthur
wiley   +1 more source

Garadacimab for the long‐term prophylaxis of hereditary angioedema

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page e1034-e1044, August 2026.
Summary Hereditary angioedema (HAE), a rare and debilitating disease characterized by recurrent and spontaneous attacks of tissue swelling, has a high unmet therapeutic need, with many patients experiencing insufficient disease control with current prophylactic treatments.
Emel Aygören‐Pürsün   +5 more
wiley   +1 more source

Aerobic Endurance Training Modulates Cardiac Renin‐Angiotensin System Peptides and Matrix Metalloproteinase Activity During Chronic Stress

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT To investigate the involvement of metalloproteinases (MMPs) in the context of endurance training and their interactions with renin‐angiotensin signalling (RAS) in stress‐induced pathophysiological responses. Trained rats were submitted to 8‐weeks of endurance treadmill training with chronic mild stress (CMS), TS rats, and without CMS (T).
Vinicius Guzzoni   +14 more
wiley   +1 more source

Interindividual variability in static apnoea performance is partly explained by genetic factors

open access: yesExperimental Physiology, Volume 111, Issue 8, Page 3718-3730, 1 August 2026.
Abstract A large interindividual variability exists in maximal apnoea duration and the physiological adjustments that occur during apnoea. Although a few genes have been found to be associated with some of the cardiovascular responses during apnoea, the extent to which genetic and environmental factors contribute to individual differences in apnoea ...
Anastasios Makris   +5 more
wiley   +1 more source

Acquired Angioedema-A Challenge in Medical Practice: A Narrative Review. [PDF]

open access: yesJ Clin Med
Poznańska-Kurowska K   +4 more
europepmc   +1 more source

Physiological mechanisms and therapeutic targets in chronic cough

open access: yesPhysiological Reports, Volume 14, Issue 15, August 2026.
Abstract Cough is a vital defensive reflex that safeguards the airways; however, it can become maladaptive and pathological. Chronic cough (>8 weeks in duration) affects up to 10% of the global adult population and is associated with considerable health status impairment. The understanding of cough physiology remains limited.
James C. Brown   +3 more
wiley   +1 more source

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