Results 81 to 90 of about 22,571 (209)

Renin‐Angiotensin Signaling and Vascular Function: Insights into Health and Disease

Acta Physiologica, Volume 242, Issue 11, November 2026.
ABSTRACT The renin‐angiotensin system (RAS) is an essential regulator of vascular structure and function, and dysregulation of angiotensin II (Ang II) signaling plays a critical role in the development of hypertension and associated vascular complications.
Giovanni Bertoldi, Swapnil K. Sonkusare
wiley   +1 more source

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3333-3353, October 2026.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili, Maurizio Evangelista, Elena Lucarini, Elena G. Giugliano, Carla Ghelardini, Laura Micheli, Lorenzo Di Cesare Mannelli   +6 more
wiley   +1 more source

An uncommon case of postpartum venous thrombosis in a patient with hereditary angioedema. Patient from the ITACA Cohort (Italian Network for Hereditary and Acquired Angioedema)

Italian Journal of Medicine
Hereditary angioedema (HAE) is a rare genetic condition characterized by episodes of cutaneous or submucosal edema, most commonly affecting the skin, the abdomen, and the upper respiratory tract. The most common cause of HAE is either a deficiency (type
Francesco Giardino, Andrea Caruso, Simone Giosuè Longhitano, Lorena Domenica Campanello   +3 more
doaj   +1 more source

Polyphenols as Natural Therapeutics for Dental Infections and Oral Inflammation: Mechanisms and Clinical Perspectives

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Polyphenol‐rich plant extracts provide natural immunomodulatory protection for oral health through complementary antioxidant, antibacterial, and anti‐inflammatory actions. Their potential to reduce harmful microbial activity and inflammation highlights the promise of dietary polyphenols as a natural strategy for maintaining oral health and preventing ...
Deepa Subramanian, Divya Krishnamoorthi, Gowtham Kannan, Benedict Mathews Paul   +3 more
wiley   +1 more source

Assembly of Bioactive Superstructures via Metal–Phenolic Complexation for Blood Purification

Angewandte Chemie, Volume 138, Issue 40, 28 September 2026.
Bioactive superstructures are assembled via metal–phenolic‐mediated assembly on agarose templates, followed by modification with human serum albumin. These superstructures demonstrate high bilirubin adsorption efficiency, strong antibacterial activity, and anticoagulant activity, providing a strategy for the rational design of multifunctional blood ...
Po Wang, Jingqu Chen, Siying Chen, Binsha Peng, Zhifeng Zhou, Ling Zhang, Rui Xie, Xiaojie Ju, Wei Wang, Dawei Pan, Liangyin Chu, Frank Caruso, Zhuang Liu   +12 more
wiley   +2 more sources

THE CORONARY VASCULATURE AND THE MYOCARDIUM

Journal of Biological Research, 1999
It has been reported that the activity of bradykinin on vascular endothelial receptors results in vasodilatation ( 1-3) due to the release of both nitric oxide (NO) and the so called endothelial-derived hyperpolarizing factor (EDHF) (4-7).
F. Ceresa, A. Delfino, A. De Matteis, N. Ferrero, M. Novarino, A. Rittà   +5 more
doaj  

Experiences From the First Year of Using Garadacimab to Treat Hereditary Angioedema and Acquired Angioedema

Clinical and Translational Allergy, Volume 16, Issue 10, October 2026.
ABSTRACT Background Garadacimab, a first‐in‐class, recombinant monoclonal antibody targeting activated FXII, is available in Germany for long‐term prophylaxis (LTP) of hereditary angioedema (HAE) since March 2025. We aimed to examine garadacimab real‐life treatment outcomes at our Berlin Angioedema Center of Reference and Excellence (ACARE), the ...
Markus Magerl, Kathrin Schön, Janine Ruhe, Felix Aulenbacher, Leonie Shirin Herzog, Thomas Buttgereit   +5 more
wiley   +1 more source

Kinin B1- and B2-Receptor Subtypes Contract Isolated Bovine Ciliary Muscle: Their Role in Ocular Lens Function and Intraocular Pressure Reduction

Pharmaceuticals
Background: Bradykinin is an endogenously produced nonapeptide with many physiological and pathological functions that are mediated by two pharmacologically defined receptor subtypes, B1- and B2-receptors.
Najam A. Sharif, Madura Kulkarni-Chitnis, Anthonia Okolie, Ya Fatou Njie-Mbye, Sunny E. Ohia   +4 more
doaj   +1 more source

Lung‐Cardiovascular Interactions and Derangements in ARDS

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez, Connor O'Brien, Matthieu Legrand, Carolyn S. Calfee, Michael A. Matthay   +4 more
wiley   +1 more source

Intraprocedural Hemodynamics During Concomitant Rheocarna Therapy and Maintenance Hemodialysis: Effects of Dialyzer Membrane Type and Circuit Sequence

Journal of Clinical Apheresis, Volume 41, Issue 5, October 2026.
ABSTRACT Chronic limb‐threatening ischemia (CLTI), a severe manifestation of peripheral artery disease, is particularly prevalent among patients receiving maintenance hemodialysis (HD) and is associated with poor limb and survival outcomes. Low‐density lipoprotein (LDL) apheresis, including Rheocarna, is used as adjunctive therapy for refractory CLTI ...
Yusuke Ishizuka, Genshin Sato, Shizuka Ishigaki, Ryo Enoki, Kako Kajiwara, Akihiko Nakasato, Sosuke Kinomura, Saori Kin, Yuji Noguchi, Daisuke Yoshizawa, Koichi Kikuchi, Michiaki Abe, Koki Kumagai, Tetsuhiro Tanaka, Koji Okamoto   +14 more
wiley   +1 more source