Gepants: targeting the CGRP pathway for migraine relief. [PDF]
Jakubowska B, Sowa-Kućma M.
europepmc +1 more source
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi +11 more
wiley +1 more source
Thyroid Metastasis From Colorectal Adenocarcinoma: A Case Report and Literature Review
Positron emission tomography‐computed tomography scan demonstrating thyroid metastasis from colorectal carcinoma in the context of metastatic disease. ABSTRACT Colorectal adenocarcinoma is one of the most common malignancies worldwide. Although metastases typically affect the liver, lungs, and peritoneum, thyroid involvement is extremely rare, with ...
Urías Hernandez Lopez +6 more
wiley +1 more source
Brain-Region-Mediated Neuroimmune Modulation in Sepsis: Research Advances and Therapeutic Prospects. [PDF]
Zhou X, Tang Y, Chen H, Huang W, Qiu H.
europepmc +1 more source
Solid Subtype of Papillary Thyroid Carcinoma: A Case Series Highlighting Aggressive Features
Hematoxylin and eosin (H&E) stained section, 40×. Tumor cells with “Orphan Annie eye” nuclei arranged in solid nests. ABSTRACT Papillary thyroid carcinoma (PTC) is the most common malignant thyroid neoplasm. Its solid/trabecular subtype (STPTC) is rare, and its aggressiveness remains controversial.
Rafael Castellanos Bueno +4 more
wiley +1 more source
A Cross-Sectional Study on Elevated Serum Calcitonin Gene-Related Peptide Levels in Rheumatoid Arthritis Patients and Their Relationship with Disease Activity. [PDF]
Dede Akpınar M, Ataoğlu S, Cangür Ş.
europepmc +1 more source
MACROPHAGE-COLONY-STIMULATING FACTOR STIMULATES SURVIVAL AND CHEMOTACTIC BEHAVIOR IN ISOLATED OSTEOCLASTS [PDF]
Chambers, TJ +5 more
core +1 more source
Glymphatic System Dysfunction in Central Nervous System Diseases
Glymphatic Dysfunction in Neurological Disorders: The glymphatic system is a brain‐wide clearance system that removes neurotoxic waste via AQP4‐mediated CSF‐ISF exchange. Dysfunction through AQP4 mislocalization, BBB injury, and inflammation annihilates clearance and causes acute (stroke, TBI) and chronic disease.
Anwar Zahran +14 more
wiley +1 more source
Extracellular ATP increases agonist potency and reduces latency at class B G protein-coupled receptors. [PDF]
Zhu S +6 more
europepmc +1 more source

