Results 211 to 220 of about 44,035 (314)

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

open access: yes
The Journal of Physiology, EarlyView.
Richard J. A. Wilson   +1 more
wiley   +1 more source

A Phase 1, Randomized, Placebo‐Controlled, Multiple‐Dose, Double‐Blind Study to Evaluate and Compare the Pharmacokinetics and Safety of Rimegepant in Healthy Adult Japanese and Caucasian Individuals

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 3, March 2026.
Abstract This Phase 1, randomized, placebo‐controlled, double‐blind study assessed the pharmacokinetic profile of rimegepant (25, 75, or 150 mg once daily for 14 days) in healthy Japanese and Caucasian adults. Exposures were modestly increased in Japanese participants compared with Caucasian participants following a single dose of rimegepant (Day 1 ...
Rajinder Bhardwaj   +6 more
wiley   +1 more source

Biological Signatures of Inflammation Biomarkers Identified Using Data Reduction Methods in Adult Population: A Scoping Review Protocol

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Chronic inflammation contributes to various chronic diseases, emphasizing the need for reliable biomarkers for early detection and understanding its causes. Measuring chronic inflammation poses challenges since most biomarkers are influenced by both acute and chronic states and recent exposures.
Gary Sánchez‐Gordón   +7 more
wiley   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

open access: yesIbrain, Volume 12, Issue 1, Page 65-85, Spring 2026.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Anterior Nasal Nerves: A Cadaveric Anatomic and Immunohistochemical Analysis

open access: yesThe Laryngoscope, Volume 136, Issue 3, Page 1158-1165, March 2026.
Anterior nasal nerves (ANNs) were identified in all cadavers, with more supplying the anterolateral nasal wall (ALNW) than the anterior portion of the inferior turbinate (IT), between the pyriform aperture (PA) and middle turbinate (MT). Both sensory and autonomic nerve markers were also identified in the ANNs.
John R. Craig   +6 more
wiley   +1 more source

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