Results 151 to 160 of about 12,370,091 (268)

Neurogenic regulation of group 2 innate lymphoid cells in asthma. [PDF]

Front Immunol
Matsuyama T, Emami Fard N, Nagashima A, Sehmi R.   +3 more
europepmc   +1 more source

The Enteric Nervous System: An Integrative Hub From Development to Systemic Physiology

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 10, Page 977-992, December 2026.
Unlike a static hardwired circuit, the ENS continuously remodels its transcriptional programs and synaptic connectivity in response to three ecological forces: microbial metabolites, immune cell signals and enteroendocrine cues. ABSTRACT The enteric nervous system (ENS) constitutes the largest and most functionally autonomous subdivision of the ...
Mario Cuchillo‐Hilario, Margarita Díaz‐Martínez, Mario Alberto Viazcan‐Carbajal, Victor David González‐Fernández   +3 more
wiley   +1 more source

CGRP-RAMP1/CALCRL Signaling Drives TGF-β2-Mediated Immune Evasion and Pancreatic Cancer Progression. [PDF]

Int J Mol Sci
Zhang B, Li Y, Fan S, Zhang J, Zhang Y, Wang W, Luo L, Xiao W, Xie X, Jian X, Han Q, Huang S, Wu M, Song Z, Wen Y, Tu H, Li S, Hu H.   +17 more
europepmc   +1 more source

Peptide‐Linked Bivalent Nanobody Constructs as Positive Allosteric Modulators of the Calcium‐Sensing Receptor

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 6, December 2026.
ABSTRACT We previously developed nanobodies acting as positive allosteric modulators (PAMs) of the calcium‐sensing receptor (CaSR). Here, we sought to develop more potent CaSR modulators by creating bivalent nanobody constructs using ‘tail‐to‐head’ peptide‐linker conjugation.
Mahdis Nabipour, Charlotte Hagen Skadhauge, Line Juel Rasmussen, Hans Bräuner‐Osborne, Jesper M. Mathiesen, Anders A. Jensen   +5 more
wiley   +1 more source

Calcitonin Receptor-stimulating Peptide, a New Member of the Calcitonin Gene-related Peptide Family [PDF]

Journal of Biological Chemistry, 2003
Takeshi Katafuchi, Katsuro Kikumoto, Kazumasa Hamano, Kenji Kangawa, Hisayuki Matsuo, Naoto Minamino   +5 more
openaire   +1 more source

Elucidating the nociceptive role of CGRP in migraine headache. [PDF]

Brain
Melo-Carrillo A, Strassman AM, Burstein R.   +2 more
europepmc   +1 more source

Reframing the Gut–Brain Axis: The Gut Wall as a Neural Immune Interface in Multiple Sclerosis and Autoimmune Neurological Diseases

Annals of Neurology, Volume 100, Issue 5, Page 915-930, November 2026.
Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini, Sean J. Pittock, Laura Cacciaguerra, Howard L. Weiner, Luke A. Schwerdtfeger   +4 more
wiley   +1 more source

Therapeutic Potential of Propolis in Ulcerative Colitis: A Review of Preclinical Evidence

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review compiles preclinical evidence from studies that investigate the therapeutic potential of propolis extracts derived from different botanical origins, as well as their main bioactive constituents, in the context of ulcerative colitis. The observed beneficial effects are primarily attributed to their antioxidant, immunomodulatory, and anti ...
Thayná Fernandes Barros, Gabriel Gomes Vila Nova, Rosane Nassar Meireles Guerra, Flavia Raquel Fernandes do Nascimento, Afonso Gomes Abreu   +4 more
wiley   +1 more source

Exosomes from mesenchymal stem/stromal cells and their therapeutic role in osteoarthritic pain. [PDF]

J Exp Orthop
Kouroupis D, Jergova S, Sagen J, Best TM.   +3 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling to Assess Transporter‐Mediated Drug–Drug Interactions in Support of Labeling Recommendations for Zavegepant Nasal Spray

Clinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1402-1413, November 2026.
Zavegepant nasal spray, a calcitonin gene‐related peptide receptor antagonist indicated for acute treatment of migraine with or without aura in adults, is a substrate for organic anion transporting polypeptide 1B3 (OATP1B3), Na+/taurocholate cotransporting polypeptide (NTCP), P‐glycoprotein (P‐gp), and cytochrome P450 3A4 (CYP3A4).
Alice Ke, Ernesto Callegari, Manthena V.S. Varma, Mayur K Ladumor, Chieko Muto, Richard J. Bertz, Hannah M. Jones, Vaishali Sahasrabudhe, Jing Liu   +8 more
wiley   +1 more source