Results 131 to 140 of about 18,546 (234)

CGRP at the Neuroimmune Interface: Regulator of Host Defense, Tumor Immunity, and Tissue Homeostasis. [PDF]

Research (Wash D C)
Gao C, Shang Y, Hu X, Wu Q, Ma L, Zou B, Liu L, Fan S.   +7 more
europepmc   +1 more source

Optimizing acupuncture dosing for hormone therapy‐induced hot flashes in cancer patients: A regression‐based analysis and narrative review

Precision Medical Sciences, Volume 15, Issue 2, Page 135-146, June 2026.
Our analysis reveals a clear dose–response relationship between acupuncture sessions and the reduction of hormone therapy‐induced hot flashes. A threshold of approximately 10 sessions establishes a robust quantitative benchmark for achieving clinically meaningful neuro‐autonomic modulation and symptom relief.
Jiaming Cui, Xinyao Wei, Lulu Bin, Shaoxin Sun, Yu Liu, Tao Yang, Zhishun Liu, Jiani Wu   +7 more
wiley   +1 more source

Irritable Bowel Syndrome Clinical Care Gaps and the Potential of Future Therapeutics Based on Peripheral Visceral Afferent Modulation. [PDF]

Clin Gastroenterol Hepatol
Camilleri M.
europepmc   +1 more source

A Combined Colon Organoid‐Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease

Phytotherapy Research, Volume 40, Issue 6, Page 3250-3266, June 2026.
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta, Elena Lucarini, Alessandra Toti, Maria Giovanna Cataldi, Clara Ciampi, Gina Rosalinda De Nicola, Lorenzo Di Cesare Mannelli, Carla Ghelardini   +7 more
wiley   +1 more source

The mechanism of different microglial receptors mediating central inflammation in chronic migraine: a meta-analysis. [PDF]

J Headache Pain
Lin X, Yu W, Lou J, Cao Z, Song W.
europepmc   +1 more source

What's Needed for a Migraine Cost‐Of‐Illness Study in Aotearoa New Zealand: Review of Data Sources and Gaps

Journal of the Royal Society of New Zealand, Volume 56, Issue 3, June 2026.
Cost of illness (COI) studies are used to quantify the economic burden of disease on health systems, employers and society, and identify where costs may be saved by improvements in disease management. Many migraine COI studies have been published internationally but none have included data from Aotearoa New Zealand (NZ), despite the known high ...
Fiona Imlach, Sofiia Tsaregorodtseva, Maite Irurzun‐Lopez, William Leung, Calvin Chan, Ray Bose   +5 more
wiley   +1 more source

Targeting CGRP signaling alleviates cancer-associated pain in oral squamous cell carcinoma. [PDF]

BMC Oral Health
Chen M, Guo Y, Liu Z, Lin C, Wang Y, Yang X, Ji T, Zhang C, Zhang Y.   +8 more
europepmc   +1 more source

Personalized‐Context‐Aware Age Gap: A New Multi‐Omics Measurement Based on Age‐Enhanced Model AOE‐Net for Aging Acceleration and Chronic Disease Risk Prediction

Aging Cell, Volume 25, Issue 6, June 2026.
Addressing systemic biases in traditional aging clocks, we introduce PAAG, a context‐aware multi‐omics metric derived from the pre‐trained AOE‐Net. PAAG accurately captures localized aging acceleration, demonstrating superior predictive power for chronic disease risks and clinical outcomes across diverse aging populations.
Feng‐Ao Wang, Tao Zeng, Chunchun Yuan, Hongyu Wang, Yule Yu, Enjin Deng, Yao Wang, Jiangxun Ji, Jiarui Cui, Dezhi Tang, Ruikun He, Yongjun Wang, Yixue Li   +12 more
wiley   +1 more source

Pharmacological mechanisms underlying neurovascular alterations related to resistant and refractory migraine: CGRP pathways and beyond. [PDF]

J Headache Pain
Scuteri D, Kodounis M, Katsuki M, Bezgal B, Bednarczyk N, Alevetsovitis SK, Wołos J, Henriques M, Pinheiro TA, MaassenVanDenBrink A, Lampl C, School of Advanced Studies of the European Headache Federation (EHF-SAS).   +11 more
europepmc   +1 more source

Respiratory Biomarkers: An Opportunity for Patient‐Centric Microsampling Approach for Treatment Optimization

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
Overview of patient centric microsampling approach for monitoring respiratory biomarkers for treatment optimization. Image created in BioRender. Khan, A. (2026) https://BioRender.com/17jm5cs. ABSTRACT The clinical heterogeneity of respiratory disorders emphasizes the need for personalized approaches to prevention, diagnosis, and therapy.
Ahmar Khan, Jacqueline L. Stair, Daniel Baker, Neil Spooner, Darragh Murnane   +4 more
wiley   +1 more source