Results 121 to 130 of about 18,546 (234)

Unraveling Inflammatory Pain: A Narrative Review of Molecular Pathways and Multidisciplinary Treatments

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Inflammatory pain is a widespread global health concern arising from complex molecular pathways triggered by a consequence of tissue damage and immune activation. It significantly impacts quality of life and functional outcomes, necessitating a comprehensive understanding of underlying mechanisms and multidisciplinary approaches for
Fatma Mohamed Elmansy, Mohamed Goda Elbqry, Saddam Ahmed Al‐Ahdal, Fatima S. O. Ashmieg, Patience Osose Nasir, Nasiru Mohammed Abdullahi, Mohammed Nader Shalaby   +6 more
wiley   +1 more source

Calcitonin Receptor-stimulating Peptide, a New Member of the Calcitonin Gene-related Peptide Family [PDF]

Journal of Biological Chemistry, 2003
Takeshi Katafuchi, Katsuro Kikumoto, Kazumasa Hamano, Kenji Kangawa, Hisayuki Matsuo, Naoto Minamino   +5 more
openaire   +1 more source

Population Pharmacokinetics and Exposure‐Response Analyses for Ubrogepant Efficacy and Safety in the Acute Treatment of Migraine: Analysis of Phase 1–3 Studies

The Journal of Clinical Pharmacology, Volume 66, Issue 6, June 2026.
Abstract A population pharmacokinetic (popPK) model was developed for ubrogepant using data from 10 Phase 1, 1 Phase 2, and 2 Phase 3 studies. The data were described by a 2‐compartment model with linear elimination and transit compartment absorption. Formulation, food intake, race, gender, and hepatic impairment had a statistically significant impact ...
Sven Stodtmann, Lucia Siovitz, Heiko Babel, Ramesh R. Boinpally   +3 more
wiley   +1 more source

Nasal Air‐Jet Sensitivity Differentiates Empty Nose Syndrome and Turbinate Reduction Patients: A Pilot Study

The Laryngoscope, Volume 136, Issue 6, Page 2491-2498, June 2026.
This prospective pilot study aims to compare nasal mucosal sensitivity to air‐jet stimuli between ENS patients and patients who underwent septoplasty/turbinate reduction (septo‐turb) surgery, but without ENS symptoms. The ENS group had a significantly higher (less sensitive) threshold than the septo‐turb group for the septum opposing the center of the ...
Kanghyun Kim, Ahmad Odeh, Jack Harness, Nidhi Jha, Veronica Formanek, Joseph Lee, Bradley Otto, Kathleen Kelly, Kai Zhao   +8 more
wiley   +1 more source

Effect of Capsaicin (8%) Topical System on Sensory Function in Patients With Diabetic Peripheral Neuropathy: Analysis of the PACE Study

Muscle &Nerve, Volume 73, Issue 6, Page 1109-1117, June 2026.
This graphical abstract provides a summary of the analysis of the PACE study that evaluated the effect of high‐concentration capsaicin topical system (HCCTS) on sensory function in patients with DPN. From left to right: Progression of untreated DPN; Research question for current analysis; Outcomes used to evaluate sensory function; Intervention; Main ...
Nathaniel P. Katz, Sam Allen, Audrey Carnevale, Lizandra Marcondes, David M. Simpson   +4 more
wiley   +1 more source

Calcitonin Gene-Related Peptide Signalling in Alcohol Use Disorders: A Scoping Review. [PDF]

Drug Alcohol Rev
Pellesi L, Ahmad TA, Guerzoni S.
europepmc   +1 more source

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

The Journal of Physiology, EarlyView.
Richard J. A. Wilson, Nicholas Jendzjowsky   +1 more
wiley   +1 more source

Preliminary real‐world trends in outpatient revenue following implementation of disease‐modifying therapies in general hospital psychiatry in Japan

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Implementation of anti‐amyloid disease‐modifying therapy (DMT) within a psychiatry‐led dementia care program enabled structural transformation of service delivery in a general hospital setting. A multidisciplinary model integrating psychiatry, neurology, and radiology facilitated coordinated care and safe treatment implementation.
Kyohei Otani, Hiroyuki Ishihara, Tetsu Nakamura, Kana Kawabe   +3 more
wiley   +1 more source

Calcitonin Gene-Related Peptide (CGRP): Biology, Signaling, Pathophysiological Roles, and Therapeutic Applications. [PDF]

Int J Mol Sci
Ramírez-Expósito MJ, Cueto-Ureña C, Martínez-Martos JM.   +2 more
europepmc   +1 more source

Headache psychiatry: A structured narrative review and integrative framework

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Headache disorders are among the most prevalent and disabling neurological conditions worldwide, yet their psychiatric comorbidities remain systematically underrecognized in clinical practice. This narrative review introduces Psychocephalology—a biopsychosocial framework conceptualizing headache through five interacting domains: neurobiology, pain ...
Kyohei Otani
wiley   +1 more source