Overview of Calcitonin Gene-Related Peptide and Its Receptor [PDF]
The Scientific World Journal, 2001 Calcitonin Gene-Related Peptide (CGRP), a 37 amino acid peptide identified as the alternately spliced gene product of calcitonin gene, is a sensory neuropeptide with potent cardiovascular effects. CGRP is distributed throughout the central and peripheral
Nambi Aiyar
doaj +5 more sources
Receptors for calcitonin, calcitonin gene related peptide, amylin, and adrenomedullin
Canadian Journal of Physiology and Pharmacology, 1995 Calcitonin, calcitonin gene related peptide, amylin, and adrenomedullin are structurally related polypeptides characterized by a six or seven amino acid ring structure linked by a disulfide bridge and an amidated C-terminus.
Roman Muff +5 more
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Calcitonin gene‐related peptide receptors in human gastrointestinal epithelia [PDF]
British Journal of Pharmacology, 1994 Calcitonin gene‐related peptide receptors in human gastrointestinal ...
HM Cox (14474847), IR Tough (14474838)
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Receptors for calcitonin gene related peptide (CGRP) in gastrointestinal epithelia
Canadian Journal of Physiology and Pharmacology, 1995 A pharmacological comparison of calcitonin gene related peptide (CGRP) receptors expressed in normal rat colon mucosa and two human adenocarcinoma cell lines has been undertaken. Using voltage-clamp techniques electrogenic ion transport was continuously
Helen M. Cox
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Calcium:Calcitonin gene-related peptide and adrenomedullin receptors
, 2021 Calcitonin gene-related peptide (CGRP), adrenomedullin (AM) and adrenomedullin 2 (AM2) are related peptides, which are potent vasodilators. The receptors for these peptides are unusual, comprising a G-protein-coupled receptor (GPCR) with receptor ...
Poyner, David +7 more
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Calcitonin Gene-Related Peptide Receptor Agonism [PDF]
Circulation, 2017 Article, see p 367 Patients with heart failure experience high rates of hospitalization and death, combined with a poor quality of life. Current treatment is aimed at increasing cardiac contractility, enhancing vasodilation, and preventing maladaptive cardiac remodeling.
Danser, Jan +1 more
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Calcitonin gene products and the kidney [PDF]
, 1989 Calcitonin gene-related peptide (CGRP) is localized in capsaicin-sensitive nerve fibres in the kidney and urogenital tract whereas calcitonin reaches the kidney through the general circulation.
Fischer, J. A. +5 more
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Calcitonin gene-related peptide is a stimulator of renin secretion [PDF]
, 1988 Calcitonin gene-related peptide (CGRP) was found to stimulate renin secretion in vivo in normal human volunteers. Moreover, CGRP stimulated the release of renin in vitro from isolated rat renal juxtaglomerular cells (half-maximal effective concentration [
Fischer, J. A. +29 more
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Activation Of Renal Pelvic Chemoreceptors In Rats: Role Of Calcitonin Gene-related Peptide Receptors. [PDF]
, 2015 Substance P and calcitonin gene-related peptide (CGRP) increase afferent renal nerve activity (ARNA). A substance P receptor antagonist but not a CGRP receptor antagonist, h-CGRP (8-37), blocks the ARNA response to renal mechanoreceptor (MR) stimulation.
Gontijo, J A, Kopp, U C
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Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes [PDF]
, 2011 Context: Increased plasma levels of glucose-dependent insulinotropic polypeptide (GIP), calcitonin CT gene-related peptide (CGRP)-I, and procalcitonin (Pro-CT) are associated with obesity.
Beat Müller +32 more
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