Results 1 to 10 of about 56,351 (295)

Molecular Insights into Epigenetics and Cannabinoid Receptors

open access: yesBiomolecules, 2022
The actions of cannabis are mediated by G protein-coupled receptors that are part of an endogenous cannabinoid system (ECS). ECS consists of the naturally occurring ligands N-arachidonylethanolamine (anandamide) and 2-arachidonoylglycerol (2-AG), their ...
Balapal S. Basavarajappa   +1 more
doaj   +1 more source

Cannabinoids and cannabinoid-like compounds: Biochemical characterization and pharmacological perspectives

open access: yesRussian Open Medical Journal, 2023
Publication interest in cannabinoids, including phytocannabinoids, endogenous cannabinoids, synthetic cannabinoids and cannabinomimetic compounds, is due to the therapeutic potential of these compounds in inflammatory pathology.
Oksana Yu. Kytikova   +3 more
doaj   +1 more source

The Endocannabinoid System Contributes to Electroacupuncture Analgesia

open access: yesFrontiers in Neuroscience, 2021
The extensive involvement of the endocannabinoid system (ECS) in vital physiological and cognitive processes of the human body has inspired many investigations into the role of the ECS and drugs, and therapies that target this system and its receptors ...
Iona J. MacDonald   +3 more
doaj   +1 more source

Cannabinoid and Cannabinoid-Related Receptors in the Myenteric Plexus of the Porcine Ileum

open access: yesAnimals, 2021
An important piece of evidence has shown that molecules acting on cannabinoid receptors influence gastrointestinal motility and induce beneficial effects on gastrointestinal inflammation and visceral pain.
Andrea Toschi   +6 more
doaj   +1 more source

Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage [PDF]

open access: yes, 2012
BACKGROUND: The endocannabinoid 2-arachidonoyl glycerol (2-AG) acts as a retrograde messenger and modulates synaptic signaling e. g. in the hippocampus. 2-AG also exerts neuroprotective effects under pathological situations.
Bechmann, Ingo Jürgen   +8 more
core   +7 more sources

The Vertical and Horizontal Pathways in the Monkey Retina Are Modulated by Typical and Atypical Cannabinoid Receptors

open access: yesCells, 2021
The endocannabinoid (eCB) system has been found in all visual parts of the central ner-vous system and plays a role in the processing of visual information in many species, including monkeys and humans. Using anatomical methods, cannabinoid receptors are
Joseph Bouskila   +4 more
doaj   +1 more source

The evolution and comparative neurobiology of endocannabinoid signalling [PDF]

open access: yes, 2012
CB(1)- and CB(2)-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid-mediated synaptic plasticity, 2-AG is generated postsynaptically by diacylglycerol ...
Devane W. A.   +4 more
core   +1 more source

Endocannabinoid-related compounds in gastrointestinal diseases [PDF]

open access: yes, 2018
The endocannabinoid system (ECS) is an endogenous signalling pathway involved in the control of several gastrointestinal (GI) functions at both peripheral and central levels.
Alessandra, D'Alessandro   +7 more
core   +1 more source

Effects of cannabinoids on ligand-gated ion channels

open access: yesFrontiers in Physiology, 2022
Phytocannabinoids such as Δ9-tetrahydrocannabinol and cannabidiol, endocannabinoids such as N-arachidonoylethanolamine (anandamide) and 2-arachidonoylglycerol, and synthetic cannabinoids such as CP47,497 and JWH-018 constitute major groups of ...
Murat Oz   +2 more
doaj   +1 more source

Cannabinoid Receptor Involvement in Stress-Induced Cocaine Reinstatement: Potential Interaction with Noradrenergic Pathways [PDF]

open access: yes, 2012
This study examined the role of endocannabinoid signaling in stress-induced reinstatement of cocaine seeking and explored the interaction between noradrenergic and endocannabinergic systems in the process.
Hillard, Cecilia J.   +6 more
core   +2 more sources

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