Results 11 to 20 of about 57,210 (209)

Cannabinoid receptors [PDF]

Current Biology, 2002
Abstract Cannabinoid receptors are seven transmembrane receptors that mediate the central and peripheral actions of extracts from the cannabis plant. Although many endogenous agonists of cannabinoid receptors have been described, a categorical role of these (mainly fatty acid derived) molecules as the endogenous ligand for cannabinoid ...
D A Kendall, S P H Alexander
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Molecular Insights into Epigenetics and Cannabinoid Receptors

Biomolecules, 2022
The actions of cannabis are mediated by G protein-coupled receptors that are part of an endogenous cannabinoid system (ECS). ECS consists of the naturally occurring ligands N-arachidonylethanolamine (anandamide) and 2-arachidonoylglycerol (2-AG), their ...
Balapal S. Basavarajappa, Shivakumar Subbanna   +1 more
doaj   +1 more source

Cannabinoids and cannabinoid-like compounds: Biochemical characterization and pharmacological perspectives

Russian Open Medical Journal, 2023
Publication interest in cannabinoids, including phytocannabinoids, endogenous cannabinoids, synthetic cannabinoids and cannabinomimetic compounds, is due to the therapeutic potential of these compounds in inflammatory pathology.
Oksana Yu. Kytikova, Yulia K. Denisenko, Tatyana P. Novgorodtseva, Ivan S. Kovalenko   +3 more
doaj   +1 more source

The Endocannabinoid System Contributes to Electroacupuncture Analgesia

Frontiers in Neuroscience, 2021
The extensive involvement of the endocannabinoid system (ECS) in vital physiological and cognitive processes of the human body has inspired many investigations into the role of the ECS and drugs, and therapies that target this system and its receptors ...
Iona J. MacDonald, Yi-Hung Chen, Yi-Hung Chen, Yi-Hung Chen   +3 more
doaj   +1 more source

Cannabinoid and Cannabinoid-Related Receptors in the Myenteric Plexus of the Porcine Ileum

Animals, 2021
An important piece of evidence has shown that molecules acting on cannabinoid receptors influence gastrointestinal motility and induce beneficial effects on gastrointestinal inflammation and visceral pain.
Andrea Toschi, Giorgia Galiazzo, Andrea Piva, Claudio Tagliavia, Gemma Mazzuoli-Weber, Roberto Chiocchetti, Ester Grilli   +6 more
doaj   +1 more source

Cannabinoids and Cannabinoid Receptors: The Story so Far [PDF]

iScience, 2020
Like most modern molecular biology and natural product chemistry, understanding cannabinoid pharmacology centers around molecular interactions, in this case, between the cannabinoids and their putative targets, the G-protein coupled receptors (GPCRs) cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2).
Fred Shahbazi, Victoria Grandi, Abhinandan Banerjee, John F. Trant   +3 more
openaire   +3 more sources

Cannabinoid receptors in invertebrates [PDF]

Journal of Evolutionary Biology, 2006
Abstract Two cannabinoid receptors, CB1 and CB2, are expressed in mammals, birds, reptiles, and fish. The presence of cannabinoid receptors in invertebrates has been controversial, due to conflicting evidence. We conducted a systematic review of the literature, using expanded search parameters. Evidence presented in the literature varied
J M, McPartland, J, Agraval, D, Gleeson, K, Heasman, M, Glass   +4 more
openaire   +2 more sources

The Vertical and Horizontal Pathways in the Monkey Retina Are Modulated by Typical and Atypical Cannabinoid Receptors

Cells, 2021
The endocannabinoid (eCB) system has been found in all visual parts of the central ner-vous system and plays a role in the processing of visual information in many species, including monkeys and humans. Using anatomical methods, cannabinoid receptors are
Joseph Bouskila, Maxime Bleau, Catarina Micaelo-Fernandes, Jean-François Bouchard, Maurice Ptito   +4 more
doaj   +1 more source

The evolution and comparative neurobiology of endocannabinoid signalling [PDF]

, 2012
CB(1)- and CB(2)-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid-mediated synaptic plasticity, 2-AG is generated postsynaptically by diacylglycerol ...
Devane W. A., Maurice R. Elphick, Montell C., Soderstrom K., Soderstrom K.   +4 more
core   +1 more source

Inactivation of anandamide signaling : A continuing Debate [PDF]

, 2010
Copyright 2011 Elsevier B.V., All rights reserved.Peer reviewedPublisher ...
Ahluwalia, Ahn, Alexander, Alexander, Beltramo, Bhave, Bifulco, Bisogno, Bisogno, Bosier, Cadas, Chen, Chuang, Clapper, Cravatt, Cravatt, Cristino, Day, De Petrocellis, De Petrocellis, De Petrocellis, Desarnaud, Deutsch, Deutsch, Devane, Devane, Di Carlo, Di Marzo, Di Marzo, Di Marzo, Egertova, Evans, Evans, Evans, Fedorova, Glaser, Guzmán, Hampson, Hanus, Harizi, Hesham Khairy, Hillard, Hillard, Hillard, Horvath, Howlett, Howlett, Iversen, Jarrahian, Jiang, Jonsson, Kaczocha, Kaczocha, Katayama, Kathuria, Khairy, Klein, Koutek, Kulkarni-Narla, Liu, Long, Maccarrone, Malcher-Lopes, Matsuda, McFarland, Mechoulam, Mechoulam, Mechoulam, Mechoulam, Miller, Moore, Mulder, Munro, Numazaki, Okamoto, Ortar, Pertwee, Piomelli, Poling, Porter, Premkumar, Randall, Schlosburg, Schmid, Simon, Stella, Stremmel, Sun, Sun, Sánchez, Thomas, Thors, Tian, Tsou, Tsuboi, Ueda, Ueda, Van den Bossche, Van Der Stelt, Wael E. Houssen, Walker, Weber, Wenger, Wood, Woodward, Yu, Zygmunt   +106 more
core   +3 more sources