Results 151 to 160 of about 43,606 (294)
Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.Abstract A 6‐year‐old, spayed, female labrador retriever was presented with left distal radial swelling. Imaging, cytology and biopsy identified an aggressive radial lesion with metastasis to the left axillary lymph node, and a diagnosis of presumptive osteosarcoma was made.
Veronica Perez‐Rodriguez +4 more
wiley +1 more source
Monocytes in Metabolic Disorders – Opportunities for Flow Cytometry Contributions [PDF]
, 2010 Chronic inflammation has arised as a major underlying cause of atherosclerosis, obesity and diabetes. It is mediated by cells of innate immune system like macrophages but also by their antecedents, circulating monocytes.
Branimir Gizdić +4 more
core +1 more source
Comprehensive Physiology, Volume 16, Issue 2, April 2026.Local complement production by pulmonary artery adventitial fibroblasts, activated intracellularly by CFD and CFB and extracellularly by GZMK+ CD8 T cells, and its secretion in soluble form and within EVs promotes macrophage and T cell chemotaxis and activation.
Hui Zhang +9 more
wiley +1 more source
Leishmania Extracellular Vesicles as a Preventive Vaccine Platform Against Leishmaniasis
Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.The potential of Leishmania‐derived extracellular vesicles (EVs) as a vaccine platform was investigated, emphasizing an affordable, GMP‐compliant production and purification method. Immunization with EV vaccines, either unadjuvanted or combined with α‐galactosylceramide (αGC), induced robust humoral and cellular immune responses, conferring protection ...
Ismail Cem Yilmaz +24 more
wiley +1 more source
The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases
MedComm, Volume 7, Issue 4, April 2026.Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi +5 more
wiley +1 more source
MedComm, Volume 7, Issue 4, April 2026.CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley +1 more source
Clinical and Translational Science, Volume 19, Issue 4, April 2026.ABSTRACT TAK‐500 is a novel immune cell–directed antibody–drug conjugate (iADC) composed of TAK‐202, an anti‐CCR2 monoclonal antibody, conjugated to the STING agonist dazostinag (TAK‐676), and is designed to stimulate antitumor immunity by reprogramming CCR2‐positive monocytes. To support clinical translation, we developed a population pharmacokinetic (
Anitha Saravanakumar +8 more
wiley +1 more source
Diabetic Medicine, Volume 43, Issue 4, April 2026.Abstract Aims Despite intensive lipid‐lowering therapy, individuals with atherosclerotic cardiovascular disease (ASCVD) exhibit residual inflammatory risk, which drives recurrent cardiovascular events. This risk is amplified in type 2 diabetes mellitus (T2DM), where a pro‐inflammatory milieu accelerates atherogenesis. Monocyte‐derived macrophages (MDMs)
J. K. Ward +4 more
wiley +1 more source
Plant Biotechnology Journal, Volume 24, Issue 4, Page 2105-2122, April 2026.ABSTRACT Mulberry is a representative economic tree species valued for both poverty alleviation and medicinal use. To advance the understanding of mulberry genomics and demography, we assembled high‐quality haploid genomes of two widely cultivated mulberry varieties NS14 and QS1, and analysed 376 accessions from 12 countries, including 39 ancient trees
Zhifeng Wang +19 more
wiley +1 more source