Results 151 to 160 of about 33,714 (244)

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun, Linqing Wen, Shiyun Tang, Lu Liu, Nianzhi Chen   +4 more
wiley   +1 more source

Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
ABSTRACT Chemokines constitute a versatile signalling network maintaining homeostasis and glia–neuron communication in the healthy brain but become progressively dysregulated during aging and Alzheimer's disease (AD). This review examines how chemokine systems transition from tightly regulated homeostatic signals to drivers of chronic neuroinflammation
Blanca I. Aldana, Kristine Freude
wiley   +1 more source

High‐Dimensional Immune Profiling Identifies Circulating NKT‐Like Cells Associated With Severity Outcome in Acute Pancreatitis at Disease Onset

Immunology, Volume 178, Issue 4, Page 685-703, August 2026.
High‐dimensional spectral cytometry of peripheral blood mononuclear cells at hospital admission revealed that acute pancreatitis patients who subsequently developed moderately‐to‐severe disease exhibited a specific reduction of circulating CD2 + CD8dim NKT‐like cells, which appear to acquire an altered cytotoxic‐like phenotype upon IL‐15 stimulation ...
Carolina González de Castro, Mª. Lourdes Ruiz Rebollo, Paloma Cal‐Sabater, Elisa Arribas‐Rodríguez, Álvaro Martín‐Muñoz, Alejandro Gonzalez del Hierro, Marina Perez Mazzali, Jessica Matesanz‐Isabel, Hugo Gonzalo‐Benito, Sara Cuesta‐Sancho, David Bernardo   +10 more
wiley   +1 more source

Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha, Holly M. Weisfelder, Thanh D. Do   +2 more
wiley   +1 more source

Avances en la terapia antirretroviral: inhibidores de entrada Update in antiretroviral therapy: entry inhibitors

Infectio, 2006
En los últimos años se ha observado una tendencia creciente en la aparición de cepas de VIH resistentes a los antirretrovirales de uso corriente.
ANA MARÍA URDANETA, MIKE VIVAS
doaj  

A Study of CD4, CCR3, CCR4, CCR5, CXCR3 Expression in Peripheral Blood Lymphocytes of Patients with Gastric Cancer

مجله دانشکده پزشکی اصفهان, 2012
Background: Based on the different expression of chemokine receptors in immune cells, we hypothesized that there would be an alteration in the relative expression of these receptors by T helper cells (Th1 and Th2) during the progression of a malignancy ...
Alireza Andalib, Hassan Dolabi, Abbas Rezaei, Mohamad Reza Maracy, Seyed Javad Hasheminia   +4 more
doaj  

New Emerging Chemokine Receptors: CCR5 or CXCR5 on Tumor Is Associated with Poor Response to Chemotherapy and Poor Prognosis in Locally Advanced Triple-Negative Breast Cancer. [PDF]

Cancers (Basel)
Cabioglu N, Onder S, Karatay H, Bayram A, Oner G, Tukenmez M, Muslumanoglu M, Igci A, Dinccag A, Ozmen V, Aydiner A, Saip P, Yavuz E.   +12 more
europepmc   +1 more source

CCR5 Utilization of Transmitted and Early Founder HIV-1 Envelopes and the Sensitivity to Small CCR5 Inhibitors [PDF]

, 2008
Huang, X, Hu, Q, Shattock, RJ
core  

CCR5+ CD8+ T Cells Are Associated with Poor Response to PD-1 Blockade Therapy. [PDF]

Int J Mol Sci
Zhao Z, Liu Y, Wu Z, Qi C, Ning Y, Lin Y, Pang X, Qiang G, Wang W.   +8 more
europepmc   +1 more source

Morphine potentiates HIV infection and receptor expression in 3d brain organoids. [PDF]

J Neurovirol
Swingler M, Tasdemir D, Cakir S, Bellizzi A, Donadoni M, Sariyer IK.   +5 more
europepmc   +1 more source