Results 1 to 10 of about 2,562,866 (332)

Cell surface receptors for CCN proteins [PDF]

Journal of Cell Communication and Signaling, 2016
The CCN family (CYR61; CTGF; NOV; CCN1-6; WISP1-3) of matricellular proteins in mammals is comprised of six homologous members that play important roles in development, inflammation, tissue repair, and a broad range of pathological processes including fibrosis and cancer.
L. Lau
openaire   +4 more sources

Approach to map nanotopography of cell surface receptors [PDF]

Communications Biology, 2022
A super-resolution localisation-based method is shown to map receptor topography in immune cells, which allows quantitative study of molecules and their interactions at the complex surface nanomorphology of cells.
Christian Franke, Tomáš Chum, Zuzana Kvíčalová, Daniela Glatzová, Gregor Jörg Gentsch, Alvaro Rodriguez, Dominic A. Helmerich, Lucas Herdly, Harsha Mavila, Otakar Frank, Tomáš Brdička, Sebastian van de Linde, Marek Cebecauer   +12 more
doaj   +5 more sources

Interaction of KSHV with Host Cell Surface Receptors and Cell Entry

Viruses, 2014
Virus entry is a complex process characterized by a sequence of events. Since the discovery of KSHV in 1994, tremendous progress has been made in our understanding of KSHV entry into its in vitro target cells.
Mohanan Valiya Veettil, Chirosree Bandyopadhyay, Dipanjan Dutta, Bala Chandran   +3 more
doaj   +2 more sources

Cell Surface Receptors in the 21st Century

AIMS Biophysics, 2014
Andrew H.A. Clayton
doaj   +5 more sources

Receptor-Mediated Muscle Homeostasis as a Target for Sarcopenia Therapeutics [PDF]

Endocrinology and Metabolism, 2021
Sarcopenia is a disease characterized by age-related decline of skeletal muscle mass and function. The molecular mechanisms of the pathophysiology of sarcopenia form a complex network due to the involvement of multiple interconnected signaling pathways ...
Jong Hyeon Yoon, Ki-Sun Kwon
doaj   +1 more source

Dimerization of cell surface receptors in signal transduction

Cell, 1995
C. Heldin
openaire   +4 more sources

Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform

eLife, 2022
Secreted proteins, which include cytokines, hormones, and growth factors, are extracellular ligands that control key signaling pathways mediating cell-cell communication within and between tissues and organs.
Dirk H Siepe, Lukas T Henneberg, Steven C Wilson, Gaelen T Hess, Michael C Bassik, Kai Zinn, K Christopher Garcia   +6 more
doaj   +1 more source

Multiple Targets for Oxysterols in Their Regulation of the Immune System

Cells, 2021
Oxysterols, or cholesterol oxidation products, are naturally occurring lipids which regulate the physiology of cells, including those of the immune system.
Lisa Reinmuth, Cheng-Chih Hsiao, Jörg Hamann, Mette Rosenkilde, John Mackrill   +4 more
doaj   +1 more source

Revising Berg-Purcell for finite receptor kinetics [PDF]

, 2021
From nutrient uptake, to chemoreception, to synaptic transmission, many systems in cell biology depend on molecules diffusing and binding to membrane receptors. Mathematical analysis of such systems often neglects the fact that receptors process molecules at finite kinetic rates.
arxiv   +1 more source

Research Progress on NK Cell Receptors and Their Signaling Pathways

Mediators of Inflammation, 2020
Natural killer cells (NK cells) play an important role in innate immunity. NK cells recognize self and nonself depending on the balance of activating receptors and inhibitory receptors. After binding to their ligands, NK cell receptors trigger subsequent
Yingying Chen, Dan Lu, Alexey Churov, Rong Fu   +3 more
doaj   +1 more source