Cell surface receptors for CCN proteins [PDF]
Journal of Cell Communication and Signaling, 2016 The CCN family (CYR61; CTGF; NOV; CCN1-6; WISP1-3) of matricellular proteins in mammals is comprised of six homologous members that play important roles in development, inflammation, tissue repair, and a broad range of pathological processes including fibrosis and cancer.
L. Lau
semanticscholar +4 more sources
Dimerization of cell surface receptors in signal transduction
Cell, 1995 C. Heldin
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An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly [PDF]
, 2010 Erythropoetin-producing hepatoma (Eph) receptors are cell-surface protein tyrosine kinases mediating cell-cell communication. Upon activation, they form signaling clusters.
A Radu Aricescu +57 more
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Current Opinion in Structural Biology, 2000 During the past year, the database of ligand-receptor complexes has essentially doubled. These new results have immeasurably extended and expanded our view of cell surface receptor structure and function. The flood of data has revealed new models for receptor cross-linking, demonstrating the potential stringency of the extracellular requirements for ...
Deller, M, Yvonne Jones, E
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Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF. [PDF]
, 2014 Pigment Epithelium Derived Factor (PEDF) is a secreted factor that has broad biological activities. It was first identified as a neurotrophic factor and later as the most potent natural antiangiogenic factor, a stem cell niche factor, and an inhibitor of
Al-Ubaidi, Muayyad +7 more
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The NAE Pathway : autobahn to the nucleus for cell surface receptors [PDF]
, 2019 Various growth factors and full-length cell surface receptors such as EGFR are translocated from the cell surface to the nucleoplasm, baffling cell biologists to the mechanisms and functions of this process. Elevated levels of nuclear EGFR correlate with
Bard, Frederic A. +3 more
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The role of cellular adhesion molecules in virus attachment and entry [PDF]
, 2015 As obligate intracellular parasites, viruses must traverse the host-cell plasma membrane to initiate infection. This presents a formidable barrier, which they have evolved diverse strategies to overcome.
Bhella, David
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Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis. [PDF]
, 2010 DNAX adaptor protein 12 (DAP12) is a trans-membrane adaptor molecule that transduces activating signals in NK and myeloid cells. Absence of functional Dap12 results in osteoclast defects and bone abnormalities.
Adamopoulos, Iannis E +11 more
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Approach to map nanotopography of cell surface receptors [PDF]
Communications Biology, 2022 AbstractCells communicate with their environment via surface receptors, but nanoscopic receptor organization with respect to complex cell surface morphology remains unclear. This is mainly due to a lack of accessible, robust and high-resolution methods.
Christian Franke +12 more
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Activation of transmembrane cell‐surface receptors via a common mechanism? The “rotation model”
Bioessays, 2015 It has long been thought that transmembrane cell‐surface receptors, such as receptor tyrosine kinases and cytokine receptors, among others, are activated by ligand binding through ligand‐induced dimerization of the receptors.
I. Maruyama
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