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Interaction of KSHV with Host Cell Surface Receptors and Cell Entry
Virus entry is a complex process characterized by a sequence of events. Since the discovery of KSHV in 1994, tremendous progress has been made in our understanding of KSHV entry into its in vitro target cells.
Mohanan Valiya Veettil+3 more
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Receptor-Mediated Muscle Homeostasis as a Target for Sarcopenia Therapeutics [PDF]
Sarcopenia is a disease characterized by age-related decline of skeletal muscle mass and function. The molecular mechanisms of the pathophysiology of sarcopenia form a complex network due to the involvement of multiple interconnected signaling pathways ...
Jong Hyeon Yoon, Ki-Sun Kwon
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Secreted proteins, which include cytokines, hormones, and growth factors, are extracellular ligands that control key signaling pathways mediating cell-cell communication within and between tissues and organs.
Dirk H Siepe+6 more
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Approach to map nanotopography of cell surface receptors
A super-resolution localisation-based method is shown to map receptor topography in immune cells, which allows quantitative study of molecules and their interactions at the complex surface nanomorphology of cells.
Christian Franke+12 more
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Multiple Targets for Oxysterols in Their Regulation of the Immune System
Oxysterols, or cholesterol oxidation products, are naturally occurring lipids which regulate the physiology of cells, including those of the immune system.
Lisa Reinmuth+4 more
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One major factor regulating the strength of GABAB receptor signaling and thereby neuronal excitability is the dynamic control of their cell surface expression.
Mohammad Hleihil+5 more
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Research Progress on NK Cell Receptors and Their Signaling Pathways
Natural killer cells (NK cells) play an important role in innate immunity. NK cells recognize self and nonself depending on the balance of activating receptors and inhibitory receptors. After binding to their ligands, NK cell receptors trigger subsequent
Yingying Chen+3 more
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Aptamers for Targeted Drug Delivery
Aptamers are a class of therapeutic oligonucleotides that form specific three-dimensional structures that are dictated by their sequences. They are typically generated by an iterative screening process of complex nucleic acid libraries employing a ...
Partha Ray, Rebekah R. White
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Research Progress of Dendritic Cell Surface Receptors and Targeting
Dendritic cells are the only antigen-presenting cells capable of activating naive T cells in humans and mammals and are the most effective antigen-presenting cells.
Chunyu Tong+6 more
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Investigations in the last 10 years have revealed a new category of neurological diseases mediated by antibodies against cell surface and synaptic proteins.
J. Dalmau, C. Geis, F. Graus
semanticscholar +1 more source