Results 1 to 10 of about 2,510,699 (306)
Cell surface receptors for CCN proteins [PDF]
Journal of Cell Communication and Signaling, 2016 The CCN family (CYR61; CTGF; NOV; CCN1-6; WISP1-3) of matricellular proteins in mammals is comprised of six homologous members that play important roles in development, inflammation, tissue repair, and a broad range of pathological processes including fibrosis and cancer.
L. Lau
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Immunosuppressive Property of MSCs Mediated by Cell Surface Receptors
Frontiers in Immunology, 2020 In the past decade, mesenchymal stem cells (MSCs) tend to exhibit inherent tropism for refractory inflammatory diseases and engineered MSCs have appeared on the market as therapeutic agents.
Siyu Liu +5 more
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Interaction of KSHV with Host Cell Surface Receptors and Cell Entry
Viruses, 2014 Virus entry is a complex process characterized by a sequence of events. Since the discovery of KSHV in 1994, tremendous progress has been made in our understanding of KSHV entry into its in vitro target cells.
Mohanan Valiya Veettil +3 more
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Cell-Surface Receptors Transactivation Mediated by G Protein-Coupled Receptors [PDF]
International Journal of Molecular Sciences, 2014 G protein-coupled receptors (GPCRs) are seven transmembrane-spanning proteins belonging to a large family of cell-surface receptors involved in many intracellular signaling cascades. Despite GPCRs lack intrinsic tyrosine kinase activity, tyrosine phosphorylation of a tyrosine kinase receptor (RTK) occurs in response to binding of specific agonists of ...
CATTANEO, FABIO +6 more
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Syndecans: multifunctional cell-surface co-receptors [PDF]
Biochemical Journal, 1997 This review will summarize our current state of knowledge of the structure, biochemical properties and functions of syndecans, a family of transmembrane heparan sulphate proteoglycans. Syndecans bind a variety of extracellular ligands via their covalently attached heparan sulphate chains.
D. Carey
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Receptor-Mediated Muscle Homeostasis as a Target for Sarcopenia Therapeutics [PDF]
Endocrinology and Metabolism, 2021 Sarcopenia is a disease characterized by age-related decline of skeletal muscle mass and function. The molecular mechanisms of the pathophysiology of sarcopenia form a complex network due to the involvement of multiple interconnected signaling pathways ...
Jong Hyeon Yoon, Ki-Sun Kwon
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eLife, 2022 Secreted proteins, which include cytokines, hormones, and growth factors, are extracellular ligands that control key signaling pathways mediating cell-cell communication within and between tissues and organs.
Dirk H Siepe +6 more
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Approach to map nanotopography of cell surface receptors
Communications Biology, 2022 A super-resolution localisation-based method is shown to map receptor topography in immune cells, which allows quantitative study of molecules and their interactions at the complex surface nanomorphology of cells.
Christian Franke +12 more
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Multiple Targets for Oxysterols in Their Regulation of the Immune System
Cells, 2021 Oxysterols, or cholesterol oxidation products, are naturally occurring lipids which regulate the physiology of cells, including those of the immune system.
Lisa Reinmuth +4 more
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Frontiers in Molecular Neuroscience, 2022 One major factor regulating the strength of GABAB receptor signaling and thereby neuronal excitability is the dynamic control of their cell surface expression.
Mohammad Hleihil +5 more
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