Results 41 to 50 of about 185,430 (311)

Spatio-temporal regulation of concurrent developmental processes by generic signaling downstream of chemokine receptors

eLife, 2018
Chemokines are secreted proteins that regulate a range of processes in eukaryotic organisms. Interestingly, different chemokine receptors control distinct biological processes, and the same receptor can direct different cellular responses, but the basis ...
Divyanshu Malhotra, Jimann Shin, Lilianna Solnica-Krezel, Erez Raz   +3 more
doaj   +1 more source

Chemokines, molecular drivers of thromboinflammation and immunothrombosis

Frontiers in Immunology, 2023
Blood clotting is a finely regulated process that is essential for hemostasis. However, when dysregulated or spontaneous, it promotes thrombotic disorders.
Julian Leberzammer, Julian Leberzammer, Julian Leberzammer, Philipp von Hundelshausen, Philipp von Hundelshausen   +4 more
doaj   +1 more source

Monocytes/macrophages express CCR9 in rheumatoid arthritis and CCL25 stimulates their differentiation [PDF]

, 2010
Introduction: Monocytes/macrophages accumulate in the rheumatoid (RA) synovium where they play a central role in inflammation and joint destruction. Identification of molecules involved in their accumulation and differentiation is important to inform ...
Buckley, Christopher, Helen Williams, Cartwright, A, John HH Williams, Andrew Filer, Schmutz, Caroline, Oliver Haworth, Filer, Andrew, Mike Salmon, Haworth, O, Buckley, Christopher D., Alison Cartwright, Christopher D Buckley, Schmutz, C, Williams, John H. H., Middleton, J, Haworth, Oliver, Buckley, CD, Williams, JH, Cartwright, Alison, Caroline Schmutz, Williams, HJ, Middleton, Jim F., Williams, Helen, Salmon, Mike, Filer, A, Salmon, M, Williams, J, Williams, H, Middleton, Jim F S, Jim Middleton   +30 more
core   +1 more source

Chemokines, Chemokine Receptors and Atherosclerosis

, 2005
Publisher Summary This chapter focuses on chemokines, chemokine receptors, and atherosclerosis. Chemokines play essential roles in inflammation and disease. This family of inflammatory mediators has diverse roles in both immune and inflammatory responses, including the regulation of cellular recruitment, activation, and differentiation.
John, A, Channon, K, Greaves, D
openaire   +2 more sources

Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation

, 2012
The recruitment of T lymphocytes during diseases such as rheumatoid arthritis is regulated by stimulation of the chemokine receptors expressed by these cells.
O'Boyle, Graeme, Palmer, Jeremy, Mavin, Emily, Kirby, John, Hine, Dominic, Barker, Catriona, Ali, Simi, Lamb, Christopher, Willet, Joseph, Fox, Christopher, Walden, Hannah   +10 more
core   +1 more source

CC Chemokine Receptors in Lung Adenocarcinoma: The Inflammation-Related Prognostic Biomarkers and Immunotherapeutic Targets

Journal of Inflammation Research, 2021
Fangteng Liu,1,2 Hengyu Wu1 1Department of Breast Surgery, The Third Hospital of Nanchang, Nanchang, Jiangxi, 330009, People’s Republic of China; 2Faculty of Medicine, University of Munich, Munich, 80336, GermanyCorrespondence: Hengyu Wu Tel +86 ...
Liu F, Wu H
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Upregulation of surface feline CXCR4 expression following ectopic expression of CCR5: implications for studies of the cell tropism of feline immunodeficiency virus [PDF]

, 2002
Feline CXCR4 and CCR5 were expressed in feline cells as fusion proteins with enhanced green fluorescent protein (EGFP). Expression of the EGFP fusion proteins was localized to the cell membrane, and surface expression of CXCR4 was confirmed by using a ...
Hosie, M.J., Willett, B.J., Cannon, C.A.
core   +1 more source

Touch of chemokines

Frontiers in Immunology, 2012
Chemoattractant cytokines or chemokines constitute a family of structurally related proteins found in vertebrates, bacteria or viruses. So far, 48 chemokines genes have been identified in humans, which bind to around 20 chemokine receptors.
Xavier eBLANCHET, Marcella eLanger, Christian eWeber, Rory R Koenen, Philipp evon Hundelshausen   +4 more
doaj   +1 more source

Regulation of Atherogenesis by Chemokines and Chemokine Receptors [PDF]

Archivum Immunologiae et Therapiae Experimentalis, 2012
Atherosclerosis is a chronic inflammatory and metabolic disorder affecting large- and medium-sized arteries, and the leading cause of mortality worldwide. The pathogenesis of atherosclerosis involves accumulation of lipids and leukocytes in the intima of blood vessel walls creating plaque.
Wuzhou, Wan, Philip M, Murphy
openaire   +2 more sources