Results 151 to 160 of about 16,141 (203)
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Cholecystokinin receptor subtypes and neuromodulation
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1989The sulfated octapeptide of cholecystokinin (CCK-8S) and CCK fragments have been administered to mice to determine the subtype and location of the CCK receptor that modulates the release of dopamine (DA) in brain. 1. Centrally (i.c.v.) or peripherally (s.c.) administered CCK-8S lowers DA release, and to a lesser extent, metabolism, in the neostriatum ...
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Ligands for Cholecystokinin A and Cholecystokinin B/Gastrin Receptors
1991Publisher Summary This chapter describes the radioligand binding assay methods used to identify and characterize the interaction of agents with the cholecystokinin-A (CCK-A) and CCK-B/gastrin receptor subtypes. The chapter also discusses the biochemical and pharmacological properties of nonpeptide CCK-A and CCK-B/gastrin antagonists, and their ...
Raymond S.L. Chang, Victor J. Lotti
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Cholecystokinin, Cholecystokinin-Receptor Antagonists and the Sphincter of Oddi
1991As a result of modern techniques like endoscopy, manometry, electromyography and hormonal assays, knowledge of the physiology and pathophysiology of sphincter of Oddi motility is now rapidly increasing. Opening of the sphincter of Oddi, once thought to be a simple passive event is a synchronized, dynamic action, involving both neural and humoral ...
J. B. M. Jansen, C. B. H. Lamers
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[Cholecystokinin and cholecystokinin receptor].
Nihon rinsho. Japanese journal of clinical medicine, 1996Cholecystokinin (CCK) act as hormones and neuropeptides on central and peripheral CCK receptors. The application of modern molecular biological techniques has identified two CCK receptors, CCK-A receptor (CCKAR) and CCK-B/gastrin receptor (CCKBR). The genes of CCKAR and CCKBR consist of five exons interrupted by four introns.
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Immunolocalisation of cholecystokinin receptors
2022This thesis was scanned from the print manuscript for digital preservation and is copyright the author. Researchers can access this thesis by asking their local university, institution or public library to make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
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Localization of cholecystokinin A and cholecystokinin B-gastrin receptors in the human stomach
Gastroenterology, 1997Gastrin and cholecystokinin (CCK) are gut-brain peptides, with multiple functions in the gastrointestinal tract mediated through CCK-B-gastrin and CCK-A receptors. The receptor localization is, however, not well established in humans. The aim of this study was to investigate the distribution and pharmacological characteristics of CCK-A and CCK-B ...
Reubi JC +6 more
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The cholecystokinin receptor antagonist CR1409 increases plasma cholecystokinin in rats
Regulatory Peptides, 1989This study was undertaken to determine whether plasma cholecystokinin (CCK) levels are affected by the administration of the CCK-receptor antagonist CR1409 to rats. Infusion of 0.19, 0.94 and 4.75 mg/kg.h CR1409 for 30 min each into 6 conscious rats increased (P less than 0.05) plasma CCK from 1.3 +/- 0.5 to 6.0 +/- 1.2, 5.4 +/- 1.2, and 5.4 +/- 1.0 pM,
J B, Jansen, A J, de Jong, C B, Lamers
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Purification of the Cholecystokinin Receptor
1990Cholecystokinin (CCK) is a gastrointestinal and neural peptide hormone with physiological activities at multiple target tissues (Mutt, 1980). These include the classical targets of the gallbladder muscularis smooth muscle and the pancreatic acinar cell (for which this hormone was named “cholecystokinin-pancreozymin”) (Ivy and Oldberg, 1928; Jorpes and ...
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Cholecystokinin and cholecystokinin receptors
Journal of Gastroenterology, 2003Kyoko, Miyasaka, Akihiro, Funakoshi
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Pyloric Cholecystokinin Receptors
1991Central or peripheral administration of the brain gut peptide cholecystokinin (CCK) results in a range of biological actions. CCK binding sites at which these actions may be mediated have been identified in multiple brain regions and at various sites in the gastrointestinal tract.
T. H. Moran +3 more
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