Results 171 to 180 of about 2,347,334 (218)
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Cholinergic receptors in corpora cavernosa

Urology, 1984
In a group of 13 patients who underwent penile surgery, a small amount of cavernosal tissue was removed and examined for content of cholinergic receptors. Three patients did not display any amount of cholinergic receptors. Values in the other 10 patients ranged from 34 to 136 femtomols.
C.J. Godec, H. Bates
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Presynaptic muscarinic cholinergic receptors

Nature, 1978
IN the isolated rabbit heart, acetylcholine inhibits the release of noradrenaline evoked by nicotinic drugs1, by KCl (ref. 2) and by sympathetic nerve stimulation3. The release of noradrenaline in response to sympathetic nerve stimulation in the rabbit heart was found to be reduced by para-sympathomimetic agonists, and atropine antagonised this effect ...
Shailesh P. Banerjee, Virendra K. Sharma
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Optimizing cholinergic tone through lynx modulators of nicotinic receptors: implications for plasticity and nicotine addiction.

Physiology, 2012
The cholinergic system underlies both adaptive (learning and memory) and nonadaptive (addiction and dependency) behavioral changes through its ability to shape and regulate plasticity.
J. Miwa, H. Lester, A. Walz
semanticscholar   +1 more source

Studies on the nature of the cholinergic receptor

European Journal of Pharmacology, 1968
Abstract The effects of a number of proteolytic enzymes on the acetylcholine sensitivity of the chronically deniervated musue membrane and on the cholinesterase activity of the innervated end-plate were examined. None of the enzymes affected the acetylcholine sensitivity, but all of them inactivated cholinesterase.
B. Sonesson   +3 more
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Immunohistochemistry of cholinergic receptors

Anatomy and Embryology, 1992
Acetylcholine and its receptors are involved in a variety of important signal transduction processes. As shown here paradigmatically for the human neuromuscular junction and the cerebral cortex, acetylcholine receptors can be visualized immunohistochemically at the cellular and subcellular level under physiological and pathological conditions.
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Cholinergic receptors and neurodegenerative diseases

Pharmaceutica Acta Helvetiae, 2000
Publisher Summary This chapter focuses on cholinergic receptors and neurodegenerative diseases. Known as the “cholinergic hypothesis of Alzheimer's disease (AD),” this hypothesis has served as the main rationale for the development of anti-AD drugs, even if alternative approaches, such as the use of neurotrophic agents, nootropics, glutamate ...
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Role of M4‐receptor cholinergic signaling in direct pathway striatal projection neurons during dopamine depletion

Synapse
Direct pathway striatal projection neurons (dSPNs) are characterized by the expression of dopamine (DA) class 1 receptors (D1R), as well as cholinergic muscarinic M1 and M4 receptors (M1R, M4R).
Avilés-Rosas Vh   +6 more
semanticscholar   +1 more source

Cholinergic receptors in insects

Trends in Biochemical Sciences, 1979
Abstract It has been suggested that cholinergic receptors in insects are neither nicotinic nor muscarinic but of a mixed nature, and hence differ from ‘classic' vertebrate receptors. However, recent evidence indicates that insects also contain distinct nicotinic and muscarinic binding-sites with properties resembling those of vertebrate receptors. The
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Cholinergic Receptor Isolation

1981
The isolation of specific cholinergic bindin protein (acetylcholine receptor = AChR) has been achieved successfully by numerous research groups (1-4, 7-9, 11, 12). The ideal source for such preparations was the electric organ of several species of Torpedo.
Peter G. Waser   +3 more
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Cholinerge Rezeptoren und Anästhesie

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie, 1992
Postsynaptic chemically controlled ion channels are a possible location for the action of anaesthetics. The nicotinic acetylcholine receptor (AcChoR) is a member of a superfamily of chemically controlled ion channels, which have a large number of structural similarities in common.
Keith W. Miller, Tonner Ph
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