Modulation of Master Transcription Factor Expression of Nile Tilapia Leukocytes via Cholinergic Pathways. [PDF]
Girón-Pérez MI +8 more
europepmc +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Targeting disrupted networks in schizophrenia: Can muscarinic drugs make a fundamental difference? [PDF]
Pratt JA, Morris BJ.
europepmc +1 more source
Peripheral Parasympathetic Networks in Pain: A Systems-Level Review of Mechanisms and Modulations. [PDF]
Yang R +7 more
europepmc +1 more source
ABSTRACT Gastroparesis is a chronic gastric motility disorder marked by delayed gastric emptying in the absence of mechanical obstruction. For patients with symptoms refractory to medical and dietary therapy, Gastric Peroral Endoscopic Myotomy (G‐POEM) has emerged as a minimally invasive, pylorus‐targeted intervention that directly addresses pyloric ...
Kobina Essilfie‐Quaye +6 more
wiley +1 more source
5-HT2A receptor enhancement of contractile activity of the porcine urothelium and lamina propria [PDF]
Alexander +29 more
core +1 more source
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna +16 more
wiley +1 more source
Morphological alterations related to depressive symptoms in mild cognitive impairment were primarily involved in emotion and affective processing, showing strong correspondence with serotonergic, dopaminergic, and GABAergic systems and enrichment of genes associated with synaptic function and excitatory neurons.
Hu Xu +9 more
wiley +1 more source
Integrative Neuroimmune Role of the Parasympathetic Nervous System, Vagus Nerve and Gut Microbiota in Stress Modulation: A Narrative Review. [PDF]
Kurhaluk N +3 more
europepmc +1 more source
Annexin A2 Causes Motor Incoordination via Muscle–Cerebellum Axis in Sarcopenia
ABSTRACT Background Sarcopenia is a prevalent age‐related disorder characterized by progressive muscle atrophy. Impaired balance is one of its most critical clinical consequences, often leading to falling and even bone fractures. As the cerebellum plays a central role in regulating motor coordination, elucidating the molecular mechanisms underlying ...
Xin Jiao +16 more
wiley +1 more source

