Results 191 to 200 of about 140,582 (304)

Genome-wide analysis reveals pathways important for the development and maturation of excitatory synaptic connections to GABAergic neurons. [PDF]

G3 (Bethesda)
Oliver DB, Ramachandran S, Biswas K, Bénard CY, Doitsidou M, McKillop H, Genao N, Lemons ML, Francis MM.   +8 more
europepmc   +1 more source

Maternal Choline Supplementation in a Mouse Model of Down Syndrome and Alzheimer’s Disease Generates Unique Expression Profile Mosaics Within Three Hippocampal Excitatory Neuronal Populations

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Maternal choline supplementation (MCS) is utilized in the Ts65Dn mouse model of Down syndrome (DS) and Alzheimer's disease (AD). At ~6 months of age, laser capture microdissection and single population RNA‐sequencing of three hippocampal neuron populations (CA1 and CA3 pyramidal neurons and dentate gyrus granule cells) were conducted.
Melissa J. Alldred, Kyrillos W. Ibrahim, Harshitha Pidikiti, Sang Han Lee, Adriana Heguy, Gabriela Chiosis, Elliott J. Mufson, Grace E. Stutzmann, Stephen D. Ginsberg   +8 more
wiley   +1 more source

Neuroimmune circuits in respiratory pathophysiology: decoding molecular crosstalk for precision therapeutic targeting. [PDF]

Ann Med
Chen Q, Jia N, Liu J, Xu C, Shen Z, Shi S, Wang F, Wang Z.   +7 more
europepmc   +1 more source

Lymphocyte Antigen 6G Mediates Vagotomy‐Associated Reduction in Body Weight

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Vagotomy was associated with lower body weight and epididymal white adipose tissue (eWAT) mass, as well as increased Ly6G+ cell infiltration in eWAT. This vagotomy‐associated weight loss was significantly attenuated in neutrophil‐deficient mice, suggesting Ly6G+ cells participate in the regulation of eWAT energy homeostasis.
Ting Liu, April S. Caravaca, Min Cai, Wanmin Dai, Jérômine Jeanne Vacquié, Qi Guo, Peter Holicek, Maxime Villet, Patricia Teixeira Mendes, Yuyang Zhang, Rubén R. Simón, Shengduo Pei, Fredrik Wermeling, Stephen G. Malin, Mikael C. I. Karlsson, Vladimir S. Shavva, Carolina E. Hagberg, Laura Tarnawski, Peder S. Olofsson   +18 more
wiley   +1 more source

Real‐Time and High‐Resolution NIR‐II‐L Imaging of Netrin‐1‐Mediated Neurovascular Coupling Driven by Dose‐Dependent Electroacupuncture

Advanced Science, Volume 13, Issue 19, 2 April 2026.
Disrupted neurovascular coupling contributes to ovarian dysfunction in polycystic ovary syndrome. Using near‑infrared II long‑wavelength imaging, this study visualizes how electroacupuncture dynamically regulates ovarian blood vessels in vivo. Immediate and cumulative stimulation elicit distinct vascular responses via a Netrin‐1 dependent mechanism ...
Yicong Wang, Zi‐Han Chen, Jiajia Li, Wei Hu, Ying Cao, Yu Wang, Xiaoyu Tong, Wenhan Lu, Yuze Yang, Yuehao Wang, Yan Xiao, Wenhao Gao, Yuning Chen, Yuyan Hou, Fan Zhang, Yi Feng   +15 more
wiley   +1 more source

Cholinergic signaling modulates intestinal pathophysiology in a Drosophila model of cystic fibrosis. [PDF]

PLoS Genet
Lane EA, Petsakou A, Liu Y, Chen W, Qadiri M, Hu Y, Perrimon N.   +6 more
europepmc   +1 more source

Cyclic alternating pattern in sleep electroencephalography as a novel predictor of dementia: A prospective study

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Cyclic alternating pattern (CAP) is a sleep physiological rhythm observed during non–rapid eye movement (NREM) stage. However, the potential role of CAP for risk of dementia remains unknown. METHODS We studied 2,557 participants enrolled in the prospective Osteoporotic Fractures in Men (MrOS) Sleep Study.
Ying Zheng, Xinyue Wu, Haizhen Chen, Fan Li, Kristine Yaffe, Katie Stone, Yue Leng, Xiao Tan   +7 more
wiley   +1 more source

Facilitation of cholinergic neurotransmission via 5-HT4 receptors in the murine gastrointestinal tract [PDF]

, 2015
Lefebvre, Romain, Pauwelyn, Vicky, Van Deynse, Els   +2 more
core  

Clinical and Biological Determinants of Longitudinal Cognitive Function in Patients With GBA1 Variants and Subthalamic Deep Brain Stimulation

Annals of Neurology, Volume 99, Issue 4, Page 976-988, April 2026.
Objective Whether cognitive decline in patients with Parkinson's disease (PD) carrying GBA1 variants is accelerated after subthalamic deep brain stimulation (STN‐DBS) remains controversial. Clarifying long‐term cognitive outcomes is essential for informed decision making.
Moritz A. Loeffler, Philipp Klocke, Isabel Wurster, Stefanie Lerche, Idil Cebi, Thomas Gasser, Alireza Gharabaghi, Kathrin Brockmann, Daniel Weiss   +8 more
wiley   +1 more source

Ginsenoside Rb1 Ameliorates Age‐Related Cognitive Impairment Potentially by Modulating the NF‐κB Signaling Pathway

Brain and Behavior, Volume 16, Issue 4, April 2026.
Ginsenoside Rb1 may alleviate age‐related cognitive impairment by suppressing hippocampal inflammation, potentially through modulation of the NF‐κB signaling pathway. Abstract Introduction: Age‐related cognitive impairment affects the quality of life of the elderly, contributing to a substantial healthcare burden.
Wei‐Feng Lu, Yu‐Zhen Zhang, Zhi‐Gang Chen, Qun‐Lin Xiao, Shi‐Ye Ke   +4 more
wiley   +1 more source