Results 231 to 240 of about 140,582 (304)

Esketamine Nasal Spray: Mechanism of Action, Clinical, and Translational Science

open access: yesClinical and Translational Science, Volume 19, Issue 4, April 2026.
ABSTRACT Major depressive disorder (MDD) imposes a substantial burden worldwide, with treatment‐resistant depression (TRD) and major depressive disorder with acute suicidal ideation or behavior (MDSI) representing two of the most severe clinical challenges.
Matthijs W. van Hoogdalem   +3 more
wiley   +1 more source

Exploring heart rate variability as a biomarker for frailty: A narrative review

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 4, April 2026.
Frailty arises from progressive multisystem dysregulation, prompting interest in biomarkers that capture declining physiological reserve. This review positions heart rate variability (HRV) within this evolving biomarker landscape, outlining its physiological basis, analytical domains and relevance to clinical research.
Luca Tagliafico   +5 more
wiley   +1 more source

Alcohol attenuates CRF-induced excitatory effects from the extended amygdala to dorsostriatal cholinergic interneurons. [PDF]

open access: yesElife
Essoh A   +14 more
europepmc   +1 more source

Neuroimmune interactions in cardiovascular homeostasis and disease. [PDF]

open access: yesAm J Physiol Cell Physiol
Toumpourleka M, Stavrakis S.
europepmc   +1 more source

Synchronous activation of striatal cholinergic interneurons induces local serotonin release. [PDF]

open access: yesNat Commun
Matityahu L   +6 more
europepmc   +1 more source

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