Results 21 to 30 of about 2,347,334 (218)
Cholinergic switch between two types of slow waves in cerebral cortex [PDF]
Cerebral Cortex 2019, 2018 Sleep slow waves are known to participate in memory consolidation, yet slow waves occurring under anesthesia present no positive effects on memory. Here, we shed light onto this paradox, based on a combination of extracellular recordings in vivo, in vitro, and computational models.
arxiv +1 more source
Revising Berg-Purcell for finite receptor kinetics [PDF]
, 2021 From nutrient uptake, to chemoreception, to synaptic transmission, many systems in cell biology depend on molecules diffusing and binding to membrane receptors. Mathematical analysis of such systems often neglects the fact that receptors process molecules at finite kinetic rates.
arxiv +1 more source
Lack of an association between SNPs within the cholinergic receptor genes and smoking behavior in a Czech post-MONICA study [PDF]
Genetics and Molecular Biology, 2014 Smoking has a significant heritable component of approximately 30-60%. Recent genome wide association studies have identified single nucleotide polymorphisms (SNPs) within the nicotinic cholinergic receptor subunits 3 (rs578776), 5 (rs16969968) and β3 ...
Jaroslav A. Hubacek +2 more
doaj +3 more sources
Selective cholinergic depletion in medial septum leads to impaired long term potentiation and glutamatergic synaptic currents in the hippocampus. [PDF]
PLoS ONE, 2012 Cholinergic depletion in the medial septum (MS) is associated with impaired hippocampal-dependent learning and memory. Here we investigated whether long term potentiation (LTP) and synaptic currents, mediated by alpha-amino-3-hydroxy-5-methyl-isoxazole-4-
Patrick M Kanju +7 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2019 The sequencing of the zebrafish genome, the emergence of powerful gene-editing tools, and the development of in vivo imaging techniques have propelled the economical zebrafish into prominence as a biomedical research model.
Robert A. Mans +5 more
doaj +1 more source
Electrophysiology of T lymphocyte cholinergic receptors. [PDF]
Proceedings of the National Academy of Sciences, 1980 The presence of functional muscarinic-cholinergic receptors on at least some T lymphocytes is suggested by the existence of saturable, high-affinity, specific muscarinic binding in T cell-enriched, but not in B cell-enriched, cell suspensions and by observed cholinergic effects on lymphocytes, (e.g., increased lytic capacity of cytotoxic lymphocytes ...
Howard M. Shapiro, Terry B. Strom
openaire +3 more sources
Front. Neural Circuits, 2014 Acetylcholine (ACh) release in the medial prefrontal cortex (mPFC) is crucial for normal cognitive performance. Despite the fact that many have studied how ACh affects neuronal processing in the mPFC and thereby influences attention behavior, there is ...
B. Bloem, R. B. Poorthuis, H. Mansvelder
semanticscholar +1 more source
Cholinergic receptor alterations in the cerebral cortex of spinal cord injured rat
Biochemistry and Biophysics Reports, 2017 Many areas of the cerebral cortex process sensory information or coordinate motor output necessary for control of movement. Disturbances in cortical cholinergic system can affect locomotor coordination.
R. Chinthu, T.R. Anju, C.S. Paulose
doaj +1 more source
Towards the convergent therapeutic potential of GPCRs in autism spectrum disorders [PDF]
arXiv, 2022 Changes in genetic and/or environmental factors to developing neural circuits and subsequent synaptic functions are known to be a causative underlying the varied socio-emotional behavioural patterns associated with autism spectrum disorders (ASD). Seven transmembrane G protein-coupled receptors (GPCRs) comprising the largest family of cell-surface ...
arxiv
Corelease of acetylcholine and GABA from cholinergic forebrain neurons
eLife, 2015 Neurotransmitter corelease is emerging as a common theme of central neuromodulatory systems. Though corelease of glutamate or GABA with acetylcholine has been reported within the cholinergic system, the full extent is unknown.
Arpiar Saunders +2 more
doaj +1 more source