Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior [PDF]
, 2003 Prenatal nicotine exposure has been linked to attention deficit hyperactivity disorder and cognitive impairment, but the sites of action for these effects of nicotine are still under investigation. High-affinity nicotinic acetylcholine receptors (nAChRs)
Caldarone, Barbara J +7 more
core +2 more sources
A Late Response on the Cholinergic Neurotransmitter System in Acute Massive Blood Loss
Общая реаниматология, 2007 Objective: to study the impact of acute massive blood loss on the properties of muscarinic cholinergic receptors and catalytic parameters of cerebral acetylcholinesterase in albino rats in the late resuscitative periods.Materials and methods. Experiments
V. L. Kozhura +5 more
doaj +1 more source
Synaptic transmission as a cooperative phenomenon in confined systems [PDF]
, 2017 In this review paper, the theory of synaptic transmission (ST) was developed and discussed. We used the hypothesis of isomorphism between: (a) the cooperative behavior of mediators --- acetylcholine molecules (ACh) and cholinoreceptors in a synaptic ...
Chalyi, A. V. +2 more
core +2 more sources
Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen +18 more
wiley +1 more source
Peripheral muscarinic receptors mediate the anti-inflammatory effects of auricular acupuncture
Chinese Medicine, 2011 Background The cholinergic and opioid systems play important roles in modulating inflammation. This study tests whether auricular acupuncture (AA) produces anti-inflammatory effects via opioid and peripheral cholinergic receptors in a rat model.
Chung Wai, Zhang Hong, Zhang Shi
doaj +1 more source
A Dopamine-Acetylcholine Cascade: Simulating Learned and Lesion-Induced Behavior of Striatal Cholinergic Interneurons [PDF]
, 2007 The "teaching signal" that modulates reinforcement learning at cortico-striatal synapses may be a sequence composed of an adaptively scaled DA burst, a brief ACh burst, and a scaled ACh pause.
Bullock, Daniel, Tan, Can Ozan
core +1 more source
Advanced Robotics Research, EarlyView.Muscle cell‐based biohybrid robot using nanomaterials for function enhancement and neural function for biomedical applications. Biohybrid robotics, an emerging field combining biological tissues with artificial systems, has made significant progress in developing various biohybrid constructs, including muscle‐cell‐driven biorobots and microbots.
Minkyu Shin +4 more
wiley +1 more source
Paying attention to smell: Cholinergic signaling in the olfactory bulb.
Frontiers in Synaptic Neuroscience, 2014 The tractable, layered architecture of the olfactory bulb (OB), and its function as a relay between odor input and higher cortical processing, makes it an attractive model to study how sensory information is processed at a synaptic and circuit level. The
Rinaldo David D'Souza +1 more
doaj +1 more source
Lesions of cholinergic pedunculopontine tegmental nucleus neurons fail to affect cocaine or heroin self-administration or conditioned place preference in rats. [PDF]
PLoS ONE, 2014 Cholinergic input to the ventral tegmental area (VTA) is known to contribute to reward. Although it is known that the pedunculopontine tegmental nucleus (PPTg) provides an important source of excitatory input to the dopamine system, the specific role of ...
Stephan Steidl, Huiling Wang, Roy A Wise
doaj +1 more source
Pharmaceuticals, 2023 Neuropathic pain affects about 7–8% of the population, and its management still poses challenges with unmet needs. Over the past decades, researchers have explored the cholinergic system (muscarinic and nicotinic acetylcholine receptors: mAChR and nAChR)
Edouard Montigné, David Balayssac
doaj +1 more source