Results 71 to 80 of about 79,884 (218)
JEADV Clinical Practice, EarlyView.This retrospective observational study analyzed a cohort of chronic urticaria (CU) patients to provide insight into the clinical practice of CU with second‐generation antihistamines (SgAHs) and to evaluate the long‐term real‐world effectiveness of rupatadine in CU. Patients with chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU)
A. M. Giménez‐Arnau +5 more
wiley +1 more source
Selectively driving cholinergic fibers optically in the thalamic reticular nucleus promotes sleep
eLife, 2016 Cholinergic projections from the basal forebrain and brainstem are thought to play important roles in rapid eye movement (REM) sleep and arousal. Using transgenic mice in which channelrhdopsin-2 is selectively expressed in cholinergic neurons, we show ...
Kun-Ming Ni +9 more
doaj +1 more source
Intratumoral Nerve Phased Development: A Promising Therapeutic Target
Medicine Bulletin, EarlyView.ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che +3 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Antiparkinson medications are effective in improving Parkinson's disease (PD) motor symptoms such as bradykinesia, tremor, and rigidity. The impact of antiparkinson medication on gait speed is less clear. Objectives The primary aim was to determine the effects of antiparkinson medication on gait speed in PD. The secondary aim was to
Anson B. Rosenfeldt +10 more
wiley +1 more source
Basal Forebrain Volume Predicts Disease Conversion in Prodromal Synucleinopathy
Movement Disorders Clinical Practice, EarlyView.Abstract Background Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal stage of Parkinson's disease (PD) and dementia with Lewy bodies (DLB). The basal forebrain (BF), a key cholinergic structure, is a site of known pathology in later stages of Lewy body disorders.
Lachlan Churchill +5 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.This study demonstrated significant treatment efficacy and safety of incobotulinumtoxinA injection in Japanese patients with chronic sialorrhea caused by Parkinson's disease and other neurological conditions. Suppression of salivary secretion and improvement in drooling symptoms were also observed throughout 48 weeks.
Nobutaka Hattori +15 more
wiley +1 more source
Thalamic Deep Brain Stimulation for Dystonic Head Tremor: A Long‐Term Study of 18 Patients
Movement Disorders Clinical Practice, EarlyView.Abstract Background Dystonic head tremor is a particular manifestation of dystonia, which is difficult to treat. Although deep brain stimulation (DBS) of the globus pallidus internus has been established as a treatment for different phenotypes of dystonia, its role in dystonic tremor has been debated.
Johanna M. Nagel +7 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn +18 more
wiley +1 more source
Acetylcholine in irritable bowel syndrome pathogenesis and the role of cholineblockers
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2011 The aim of review. To demonstrate value of disorders of cholinergic innervation in pathogenesis of irritable bowel syndrome (IBS).Original positions. The important place in regulation of gastro-intestinal tract functions belongs not only to M-, but also ...
Yu. O. Shulpekova
doaj
Movement Disorders Clinical Practice, EarlyView.Abstract Background Anticholinergic medications and botulinum neurotoxin injections are established treatments for dystonia, yet they carry potential side effects and practical challenges. Deep brain stimulation (DBS) is offered in case of poor response to these approaches.
Marcela A. Montiel +5 more
wiley +1 more source