Results 11 to 20 of about 3,062,816 (304)

Complement peptide receptors in GtoPdb v.2021.3 [PDF]

open access: yes, 2021
Complement peptide receptors (nomenclature as agreed by the NC-IUPHAR subcommittee on Complement peptide receptors [107]) are activated by the endogenous ~75 amino-acid anaphylatoxin polypeptides C3a and C5a, generated upon stimulation of the complement ...
Cianciulli, Antonia   +8 more
core   +2 more sources

Effects of immobilized immune complexes on Fc- and complement-receptor function in resident and thioglycollate-elicited mouse peritoneal macrophages [PDF]

open access: yes, 1979
We have examined the Fc- and complement-receptor function of resident and thioglycollate-elicited mouse peritoneal macrophages plated on surfaces coated with rabbit antibody-antigen complexes and with complement.
Michl, Josef   +3 more
core   +4 more sources

Complement peptide receptors in GtoPdb v.2023.1 [PDF]

open access: yes, 2023
Complement peptide receptors (nomenclature as agreed by the NC-IUPHAR subcommittee on Complement peptide receptors [113]) are activated by the endogenous ~75 amino-acid anaphylatoxin polypeptides C3a and C5a, generated upon stimulation of the complement ...
Cianciulli, Antonia   +8 more
core   +2 more sources

Helix 8 in chemotactic receptors of the complement system.

open access: yesPLoS Computational Biology, 2022
Host response to infection involves the activation of the complement system leading to the production of anaphylatoxins C3a and C5a. Complement factor C5a exerts its effect through the activation of C5aR1, chemotactic receptor 1, and triggers the G ...
Szymon Wisniewski   +3 more
doaj   +1 more source

Receptor-Mediated NETosis on Neutrophils

open access: yesFrontiers in Immunology, 2021
Neutrophil extracellular traps (NETs), a web-like structures containing chromatin, have a significant role in assisting the capture and killing of microorganisms by neutrophils during infection.
Tao Chen   +19 more
doaj   +1 more source

C3‐dependent effector functions of complement

open access: yesImmunological Reviews, 2022
C3 is the central effector molecule of the complement system, mediating its multiple functions through different binding sites and their corresponding receptors. We will introduce the C3 forms (native C3, C3 [H2O], and intracellular C3), the C3 fragments
A. Zarantonello   +3 more
semanticscholar   +1 more source

The many roles of C1q

open access: yeseLife, 2020
The ability of a well-known component of the complement cascade to bind to a variety of receptors has implications for signaling biology, spinal cord injury and, possibly, the evolution of the complement system.
Mark Noble, Christoph Pröschel
doaj   +1 more source

Complement System: An Immunotherapy Target in Colorectal Cancer

open access: yesFrontiers in Immunology, 2022
Colorectal cancer (CRC) is the third most common malignant tumor and the second most fatal cancer worldwide. Several parts of the immune system contribute to fighting cancer including the innate complement system.
Iman M. Talaat   +7 more
doaj   +1 more source

RECEPTORS FOR COMPLEMENT ON LEUKOCYTES [PDF]

open access: yesThe Journal of Experimental Medicine, 1968
Sheep red blood cells sensitized by 7S, but not by 19S rabbit anti-Forssman antibodies, adhere and form rosettes on mouse macrophages and on a few monocytes and polymorphonuclear cells (PMN). When, however, C' factors from mouse serum are added to the antigen-19S antibody complex (EAC'), rosettes are formed on most mouse peritoneal macrophages and PMN ...
Waltraut H. Lay, Victor Nussenzweig
openaire   +2 more sources

Properdin Modulates Complement Component Production in Stressed Human Primary Retinal Pigment Epithelium Cells

open access: yesAntioxidants, 2020
The retinal pigment epithelium (RPE) maintains visual function and preserves structural integrity of the retina. Chronic dysfunction of the RPE is associated with retinal degeneration, including age-related macular degeneration (AMD).
Nicole Schäfer   +6 more
doaj   +1 more source

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