Results 21 to 30 of about 198,221 (310)

A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo [PDF]

, 2000
The strongest susceptibility genes for the development of systemic lupus erythematosus (SLE) in humans are null mutants of classical pathway complement proteins. There is a hierarchy of disease susceptibility and severity according to the position of the
H. Terence Cook, Savill, John, Henson, Peter M, Cook, HT, Valerie A. Fadok, Taylor, P.R, Henson, PM, Mark J. Walport, Savill, JS, Walport, MJ, Philip R. Taylor, John S. Savill, Michael C. Carroll, Botto, M, Andrews, Mark, Taylor, PR, Fadok, Valerie A, Anna Carugati, Carroll, Michael C, Walport, Mark J, Carroll, MC, Marina Botto, Carugati, A, Peter M. Henson, Andrews, M, Mark Andrews, Botto, Marina, Fadok, VA, Carugati, Anna, Cook, H. Terence   +29 more
core   +1 more source

Structural Immunology of Complement Receptors 3 and 4

Frontiers in Immunology, 2018
Complement receptors (CR) 3 and 4 belong to the family of beta-2 (CD18) integrins. CR3 and CR4 are often co-expressed in the myeloid subsets of leukocytes, but they are also found in NK cells and activated T and B lymphocytes.
Thomas Vorup-Jensen, Thomas Vorup-Jensen, Rasmus Kjeldsen Jensen   +2 more
doaj   +1 more source

Complement peptide receptors in GtoPdb v.2021.3

, 2021
Complement peptide receptors (nomenclature as agreed by the NC-IUPHAR subcommittee on Complement peptide receptors [107]) are activated by the endogenous ~75 amino-acid anaphylatoxin polypeptides C3a and C5a, generated upon stimulation of the complement ...
Lee, John D., Monk, Peter, Mitolo, Vincenzo, Woodruff, Trent M., Coulthard, Liam, Cianciulli, Antonia, Panaro, Maria A., Li, Xaria X., Hawksworth, Owen   +8 more
core   +1 more source

Role of Complement and Histones in Sepsis

Frontiers in Medicine, 2020
The wide use of the mouse model of polymicrobial sepsis has provided important evidence for events occurring in infectious sepsis involving septic mice and septic humans.
Firas S. Zetoune, Peter A. Ward
doaj   +1 more source

CR2 Complement Receptor

Journal of Investigative Dermatology, 1990
CR2, a membrane glycoprotein, is one of a number of cell-surface proteins which bind activation and processing fragments of the complement system. CR2, which is found on normal B lymphocytes, follicular dendritic cells in lymphoid organs, and epithelial cells, interacts preferentially with C3dg, the terminal activation/processing fragment of the third ...
Cooper, Neil R, Bradt, Bonnie M, Rhim, Johng S, Nemerow, Glen R   +3 more
openaire   +2 more sources

Innate immunity and neuroinflammation [PDF]

, 2013
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Kishore, U, Domenico Marco Bonifati, Abhishek Shastri, Shastri, A, Bonifati, DM, Uday Kishore   +5 more
core   +1 more source

Alteration in Leukocyte Subsets and Expressions of FcγR and Complement Receptors among Female Ragpickers in Eastern India

Safety and Health at Work, 2017
Background: There are a million ragpickers in India who gather and trade recyclable municipal solid wastes materials for a living. The objective of this study was to examine whether their occupation adversely affects their immunity. Methods: Seventy-four
Nandan K. Mondal, Shabana Siddique, Madhuchanda Banerjee, Sanghita Roychoudhury, Sayali Mukherjee, Mark S. Slaughter, Twisha Lahiri, Manas R. Ray   +7 more
doaj   +1 more source

Properdin and factor H: Opposing players on the alternative complement pathway "see-saw" [PDF]

, 2013
This article has been made available through the Brunel Open Access Publishing Fund.Properdin and factor H are two key regulatory proteins having opposite functions in the alternative complement pathway.
Kouser, L, Cordula M. Stover, Munirah Abdul-Aziz, Robert B. Sim, Nayak, A, Lubna Kouser, L. Kouser (7639589), Kishore, U, M. Abdul-Aziz (7677725), R. B. Sim (7584038), U. Kishore (7639601), Cordula M. Stover (7117046), Abdul-Aziz, M, Annapurna Nayak, A. Nayak (7334981), Stover, CM, Sim, RB, Uday Kishore   +17 more
core   +1 more source

Complement peptide receptors in GtoPdb v.2023.1

, 2023
Complement peptide receptors (nomenclature as agreed by the NC-IUPHAR subcommittee on Complement peptide receptors [113]) are activated by the endogenous ~75 amino-acid anaphylatoxin polypeptides C3a and C5a, generated upon stimulation of the complement ...
John D. Lee, Lee, John D., Xaria X. Li, Antonia Cianciulli, Hawksworth, Owen, Owen Hawksworth, Monk, Peter, Liam Coulthard, Peter Monk, Vincenzo Mitolo, Mitolo, Vincenzo, Maria A. Panaro, Woodruff, Trent M., Coulthard, Liam, Trent M. Woodruff, Cianciulli, Antonia, Panaro, Maria A., Li, Xaria X.   +17 more
core   +1 more source

Neuropilin-1 Acts as a Receptor for Complement Split Products

Frontiers in Immunology, 2019
Complement split products (CSPs), such as the fragments C4d and C3d, which are generated as a consequence of complement regulatory processes, are established markers for disease activity in autoimmunity or antibody-mediated graft rejection.
Claire Battin, Annika De Sousa Linhares, Wolfgang Paster, Wolfgang Paster, David E. Isenman, Markus Wahrmann, Judith Leitner, Gerhard J. Zlabinger, Peter Steinberger, Johannes Hofer   +9 more
doaj   +1 more source