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Complement Receptors in HIV Infection
Current Molecular Medicine, 2002Similar to other pathogens, HIV can directly activate the complement pathway even in the absence of antibodies. During and after seroconversion, HIV-specific antibodies enhance the activation of complement and increase deposition of complement fragments on virions dramatically.
Susi, Doepper +4 more
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Assays for Membrane Complement Receptors
Current Protocols in Immunology, 1994AbstractLeukocytes express several types of receptors for activated products of the complement (C) system. This unit describes assays for a subset of these receptors: those specific for fixed fragments of C3 (CR1, CR2, CR3, and CR4). Although the assays have been designed for tests of human C receptors, they can often be carried out with rodent (e.g ...
Lynda D, O'Rear, Gordon D, Ross
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Complement Receptors in Shock and Transplantation
Archives of Surgery, 1993Over the last decade, elegant studies of the basic biologic characteristics of inflammation and tissue injury have implicated leukocyte-mediated vascular and tissue injury in the pathogenesis of a wide variety of immune and inflammatory clinical disorders, including allograft rejection, adult respiratory distress syndrome, and shock. Recognition of the
E A, Deitch, M C, Mancini
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Complement receptor structure and function
Immunology Today, 1985Membrane complement receptors (CRs) are now recognized as important cell-bound components of the complement system and research into the structure and function of complement receptors is one of the main thrusts of current complement research.
G D, Ross, J P, Atkinson
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Complement receptors in HIV infection
Immunological Reviews, 1997SummaryThe complement system plays an important role in the antimicrobial defense of the organism. Its components recognize a large variety of pathogens and target them for destruction, either directly by formation of a membrane attack complex or indirectly by recruiting phagocytic cells.
C, Speth, L, Kacani, M P, Dierich
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Complement Receptors and B Lymphocytes
Critical Reviews™ in Immunology, 2004Most of the biological processes depend on cell-to-cell and protein-to-cell interactions, which take place through receptors present on the cell surface. Various physiological systems are linked by such interactions, as is the case for innate and adaptative immune response.
Marie-Bernadette, Villiers +3 more
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Complement Receptor 2 and Autoimmunity
2003Complement receptor 2 (CR2/CD21) plays a major role in the immune response by linking innate and adaptive immunity to foreign pathogens and proteins. In addition, several lines of evidence strongly support a role for CR2 in the maintenance of tolerance to self-antigens.
V Michael, Holers, Susan A, Boackle
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THE ROLE OF COMPLEMENT AND COMPLEMENT RECEPTORS IN INDUCTION AND REGULATION OF IMMUNITY
Annual Review of Immunology, 1998▪ Abstract Covalent attachment of activated complement C3 (C3d) to antigen links innate and adaptive immunity by targeting antigen to follicular dendritic cells (FDC) and B cells via specific receptors CD21 and CD35. Recent characterization of knockout mice deficient in complement components C3, C4, or the receptors CD21 and CD35 as well as ...
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Complement Receptors, Adhesion, and Phagocytosis
2008Phagocytosis is an essential component of host defense against invading pathogens. Although many cell types can ingest particulate material, "professional phagocytes" perform this function much more efficiently than other cells because they express unique membrane proteins and signal transduction mechanisms.
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