Results 61 to 70 of about 18,708 (168)

On the role of corticotropin-releasing hormone receptors in anxiety and depression

Dialogues in Clinical Neuroscience, 2002
On the basis of extensive basic and clinical studies, corticotropin-releasing hormone (CRH) and its related family members are considered to play a pivotal role in stress-related disorders, such as anxiety and depression. CRH is regarded as the principal mediator in the brain of the stress response, as it mediates neuroendocrine, autonomic, and ...
Reul, Johannes M H M, Holsboer, Florian
openaire   +3 more sources

Role and action mechanisms of tPA in CRH-induced apoptosis of mouse oviductal epithelial and mural granulosa cells

The Journal of Reproduction and Development
Understanding how stress hormones induce apoptosis in oviductal epithelial cells (OECs) and mural granulosa cells (MGCs) can reveal the mechanisms by which female stress impairs embryonic development and oocyte competence.
Yong-Qing YANG, Min ZHANG, Qi HUA, Rui-Jie MA, Xiao-Yan WANG, Hong-Jie YUAN, Ming-Jiu LUO, Jing-He TAN   +7 more
doaj   +1 more source

Skin Corticotropin-Releasing Hormone Receptor Expression in Psoriasis [PDF]

Journal of Investigative Dermatology, 2007
Tagen, Michael, Stiles, Linsey, Kalogeromitros, Demetrios, Gregoriou, Stamatios, Kempuraj, Duraisamy, Makris, Michael, Donelan, Jill, Vasiadi, Magdalini, Staurianeas, Nikolaos G., Theoharides, Theoharis C.   +9 more
openaire   +3 more sources

The role of psychological stress in the pathogenesis of psoriasis

Frontiers in Medicine
Psoriasis is an immune-mediated dermatosis characterized by systemic inflammation and multifactorial pathogenesis. Among its many triggers, psychological stress has emerged as a pivotal yet underappreciated contributor to disease onset and exacerbation ...
Dongyun Lei, Canyi Gong, Bin Wang, Litao Zhang, Guoqiang Zhang, Guoqiang Zhang, Mao-Qiang Man   +6 more
doaj   +1 more source

Single cocaine exposure attenuates the intrinsic excitability of CRH neurons in the ventral BNST via Sigma-1 receptors

Translational Neuroscience
The ventral bed nucleus of the stria terminalis (vBNST) plays a key role in cocaine addiction, especially relapse. However, the direct effects of cocaine on corticotropin-releasing hormone (CRH) neurons in the vBNST remain unclear. Here, we identify that
Wu Jintao, Zhao Yue
doaj   +1 more source

Role of CRH in colitis and colitis-associated cancer: a combinative result of central and peripheral effects?

Frontiers in Endocrinology
Corticotropin-releasing factor family peptides (CRF peptides) comprise corticotropin releasing hormone (CRH), urocortin (UCN1), UCN2 and UCN3. CRH is first isolated in the brain and later with UCNs found in many peripheral cells/tissues including the ...
Chao Zhu, Shengnan Li
doaj   +1 more source

Chronic Nicotine Consumption and Withdrawal Regulate Melanocortin Receptor, CRF, and CRF Receptor mRNA Levels in the Rat Brain

Brain Sciences
Alterations in the various neuropeptide systems in the mesocorticolimbic circuitry have been implicated in negative effects associated with drug withdrawal.
Oguz Gozen, Buket Aypar, Meliha Ozturk Bintepe, Fulya Tuzcu, Burcu Balkan, Ersin O. Koylu, Lutfiye Kanit, Aysegul Keser   +7 more
doaj   +1 more source

Urocortin2 measurement for heart failure assessment

Scientific Reports
Despite the efficacy of many therapies for heart failure, it remains a leading cause of morbidity and mortality worldwide, with many patients progressing to advanced stages of the condition.
Kohei Inukai, Kazuya Miyashita, Kazuhiko Kotani, Ryota Morimoto, Toru Kondo, Hiroaki Hiraiwa, Shingo Kazama, Tatsuya Yoshida, Satoya Yoshida, Tomoki Hattori, Kumiko Fukamachi, Naoya Fukui, Katsuhiro Kato, Yoshimitsu Yura, Koji Ohashi, Noriyuki Ouchi, Toyoaki Murohara, Takahiro Okumura, Mikito Takefuji   +18 more
doaj   +1 more source

Corticotropin releasing hormone receptor 1 (CRHR1; CRFR1) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

An exploratory microarray analysis of estrogen-mediated gene expression in central pathways that control energy balance in female rats (Rattus norvegicus). [PDF]

BMC Res Notes
Lang H, Burch K, Sloan D.
europepmc   +1 more source