MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Application of Agents Against Interferon-Gamma-Dependent Chemokines in Immunotherapy [PDF]
, 2015 The CXC chemokine receptor (CXCR) 3 and its chemokines (CXCL9, CXCL10, CXCL11) are involved in the pathogenesis of autoimmune disesases. Under the influence of interferon (IFN) γ, the IFNγ-inducible chemokines are secreted by lymphocytes, and by ...
Antonelli, Alessandro +4 more
core +1 more source
Cytokines and therapy in COPD: a promising combination? [PDF]
, 2002 COPD is a major health problem, with patients showing a progressively declining, largely irreversible, change in lung function. This is associated with chronic airways inflammation and structural remodeling, including loss of alveolar ...
Boer, W.I. (Pim) de
core +1 more source
Tumor-associated neutrophils: new targets for cancer therapy [PDF]
, 2019 Na tumorsku progresiju utječu brojni tipovi imunosnih stanica domaćina, a važna uloga neutrofila nije još potpuno jasna. Iako rana istraživanja pokazuju da neutrofili mogu ispoljavati citotoksičnost prema tumorskim stanicama preko regulacije ...
Gagić, Sanja
core +2 more sources
Chemokines in depression in health and in inflammatory illness: a systematic review and meta-analysis [PDF]
, 2018 Inflammatory illness is associated with depression. Preclinical work has shown that chemokines are linked with peripheral–central crosstalk and may be important in mediating depressive behaviours.
Cavanagh, J. +5 more
core +1 more source
New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities [PDF]
, 2015 CXCR4 is a target of growing interest for the development of new therapeutic drugs and imaging agents as its role in multiple disease states has been demonstrated.
Archibald, Stephen J. +14 more
core +2 more sources
Characterization of amoxicillin‐ and clavulanic acid‐specific T cells in patients with amoxicillin‐clavulanate–induced liver injury [PDF]
, 2015 Drug‐induced liver injury (DILI) frequently has a delayed onset with several human leukocyte antigen (HLA) genotypes affecting susceptibility, indicating a potential role for the adaptive immune system in the disease.
Abajo +33 more
core +1 more source
Attenuation of murine allergic airway inflammation with a
Clinical & Experimental Allergy, 2018 Koa Hosoki +2 more
openaire +2 more sources
Expresión de Receptores de Quimiocinas (CXCR-4 y CCR-5) en Placenta Humana Normal a Término
, 2005 La interfase materno-fetal posee un Sistema Inmunitario (SI) activo cuyos mediadores -células, citocinas y quimiocinas-, intervienen coordinadamente para favorecer el desarrollo normal del embarazo. No se conoce con exactitud cuales de esos mediadores están presentes en cada estrato celular de la placenta y cuales pueden ser las consecuencias ...
Bustamante, Suhjeys +7 more
openaire +1 more source
In Silico Studies on DARC. [PDF]
, 2009 International audienceThe Duffy Antigen/Receptor for Chemokine (DARC) is a seven segment transmembrane protein. It was firstly discovered as a blood group antigen and was the first specific gene locus assigned to a specific autosome in man.
Autin, Ludovic +4 more
core +2 more sources