Results 51 to 60 of about 11,764 (203)
ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler +4 more
wiley +1 more source
Медицинская иммунология, 2014 Аbstract. Endometrial hyperplasia (EH) represents an excessive increase in thickness and volume of proliferating endometrium accompanied by altered glandular structure.
N. V. Kipich +4 more
doaj +1 more source
Human Genomics, 2019 Background Age-related macular degeneration (AMD) is the most common, progressive, and polygenic cause of irreversible visual impairment in the world. The molecular pathogenesis of the primary events of AMD is poorly understood.
Madhu Sudhana Saddala +5 more
doaj +1 more source
Charakterisierung der Regulation und Funktion von PPARbeta [PDF]
, 2006 Im Zusammenhang mit Tumorerkrankungen kristallisierte sich in den letzten Jahren eine Gruppe von Kernrezeptoren heraus, die zunehmend mit Prozessen wie dem Zellzyklus, der Apoptose oder der Angiogenese in Verbindung gebracht wurden - die Familie der ...
Fauti, Tanja, Müller, Rolf (Prof.)
core +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
iNew Medicine, EarlyView.ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Genetic Polymorphisms of the Glucocorticoid Receptor and Interleukin-8 Receptor Genes are Related to Production Traits and Hair Coat Score in Crossbred Cattle [PDF]
, 2017 The objective of this thesis was to identify polymorphisms in the glucocorticoid receptor (GR) and interleukin-8 receptor (CXCR2) genes and to associate genotypes between the above mentioned polymorphisms and production traits in crossbred cattle.
Deaton, Avery
core +2 more sources
Exosome-mediated crosstalk between chronic myelogenous leukemia cells and human bone marrow stromal cells triggers an interleukin 8-dependent survival of leukemia cells [PDF]
, 2014 Chronic myelogenous leukemia (CML) is a myeloproliferative disorder characterized by the Bcr–Abl oncoprotein with constitutive tyrosine kinase activity.
ALESSANDRO, Riccardo +5 more
core +1 more source
Allergy, EarlyView.ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source
Variation in the CXCR1 gene (IL8RA) is not associated with susceptibility to chronic periodontitis [PDF]
, 2011 Background: The chemokine receptor 1 CXCR-1 (or IL8R-alpha) is a specific receptor for the interleukin 8 (IL-8), which is chemoattractant for neutrophils and has an important role in the inflammatory response.
Raquel M Scarel-Caminaga +8 more
core +1 more source
Recombinant DnaK orally administered protects axenic European sea bass against vibriosis [PDF]
, 2020 Vibrio anguillarum causes high mortality in European sea bass (Dicentrarchus labrax) larviculture and is a hindering factor for successful sustainable aquaculture of this commercially valuable species.
Bajek, Aline +6 more
core +2 more sources