Results 151 to 160 of about 22,074 (250)

Prolonged ruxolitinib cream treatment for vitiligo among patients with no or limited response in the first 6 months

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Albert Wolkerstorfer, Melinda J. Gooderham, Michael Sebastian, David Rosmarin, Andrew Blauvelt, Maryam Shayesteh Alam, Jacek Zdybski, Shaoceng Wei, Deanna Kornacki, Thierry Passeron, John E. Harris   +10 more
wiley   +1 more source

Understanding the Molecular Landscape of Alopecia Areata: Key Genes, Regulatory Networks, and Therapeutic Targets

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Introduction Alopecia areata (AA) is an autoimmune disorder characterized by hair loss due to immune‐mediated destruction of hair follicles. The polygenic nature of AA, influenced by genetic and environmental factors, complicates its pathogenesis.
Ahmed Ibrahim AbdElneam, Mohammed Saleh Al‐Dhubaibi, Saleh Salem Bahaj, Ghada Farouk Mohammed, Lina Mohammed Atef   +4 more
wiley   +1 more source

CD4+ T-cell localization to the large intestinal mucosa during Trichuris muris infection is mediated by Gαi-coupled receptors but is CCR6- and CXCR3-independent

, 2010
Infection of mice with the gastrointestinal nematode Trichuris muris represents a valuable tool to investigate and dissect intestinal immune responses. Resistant mouse strains respond to T. muris infection by mounting a T helper type 2 response. Previous
Svensson, Marcus, Kathryn J. Else, Svensson Frej, Marcus,, Russell, Karen, Karen Russell, Svensson Frej, Marcus, Marcus Svensson, Lund University., Else, Kathryn J., MacK, Matthias, Matthias Mack   +10 more
core   +1 more source

CD8+ Tissue‐Resident Memory T Cells in Health and Disease

MedComm, Volume 7, Issue 7, July 2026.
CD8+ TRM cells are at the center of immunity, mediating potent local innate and adaptive immune responses. While TRM cells mediate protective immunity against infections and tumors, they also contribute to pathological inflammation in autoimmune conditions.
Yu‐Han Ai, Ting‐Ting Xu, Sen Lin, Meng‐Yu Xiao, Yun‐Xia Lin, Hao‐Wen Ma, Yue‐Yang Liu, Yao‐Jie Wang, Lu‐Ning Yin, Mei Huang, Yong‐Da Liu, Chao Zhu, Xiao‐Ting Zhu, Ji‐Hang Yuan   +13 more
wiley   +1 more source

Whole Blood Transcriptomic Response to Perioperative Dexamethasone in Total Knee Arthroplasty: A Targeted Panel Analysis

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Changes in the transcriptome of immune cells are predictive of clinical outcomes. These effects may be surgery‐specific and possibly modulated by glucocorticoids. We investigated the immune response and the impact of dexamethasone on the response in patients undergoing total knee arthroplasty (TKA). Methods The transcript levels (n =
Asger Krog Mølgaard, Kasper Smidt Gasbjerg, Lukas Balsevicius, Britt Cappelen, Adile Orhan, Helin Yikilmaz Pardes, Ole Mathiesen, Thomas Litman, Daniel Hägi‐Pedersen, Ismail Gögenur   +9 more
wiley   +1 more source

Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation [PDF]

The recruitment of T lymphocytes during diseases such as rheumatoid arthritis is regulated by stimulation of the chemokine receptors expressed by these cells.
Hine DW, Walden HR, Fox CR, Willet JD, Ali S, Kirby JA, O'Boyle G, Lamb CA, Mavin ER, Barker CE, Palmer JM   +10 more
core  

HIV Transmission and Immunology of the Male Reproductive Tract

American Journal of Reproductive Immunology, Volume 96, Issue 1, July 2026.
ABSTRACT The penile epithelium, encompassing multiple anatomical sites, is the primary location of human immunodeficiency virus (HIV) acquisition in heterosexual men. Although the per‐contact risk of penile HIV acquisition is generally low, substantial global discrepancies in HIV prevalence still exist, particularly in low‐income regions.
Jinny Tsang, Rachel Liu, Rameen Jamil, Ronald Moses Galiwango, Brenda Okech, Sanja Huibner, Marcio Gabriel A. de Carvalho, Lane B. Buchanan, Cindy M. Liu, Aaron A. R. Tobian, Jessica L. Prodger, Rupert Kaul   +11 more
wiley   +1 more source

New‐Onset Vitiligo During Dupilumab Treatment: A Clinical Observation and Literature Review

The Clinical Respiratory Journal, Volume 20, Issue 7, July 2026.
Dupilumab rarely induces new‐onset vitiligo, even after discontinuation of the drug, potentially through the activation of the Th1/IFN‐γ pathway following IL‐4R blockade. Female sex and the use of topical corticosteroids are associated with improved outcomes, whereas discontinuing dupilumab alone does not ensure repigmentation.
Xuhui Pu, Suzhen Ju, Yanfang Yu
wiley   +1 more source

Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer

Immunology, Volume 178, Issue 3, Page 377-386, July 2026.
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros, Gabriel Augusto Leite, Arthur Gomes de Andrade, Maria Danielma dos Santos Reis, Luiz Henrique Agra Cavalcante‐Silva, Marvin Paulo Lins   +5 more
wiley   +1 more source

From monoclonal to polyfunctional immunotherapy: Reprogramming CAR‐T‐cell therapy with oncolytic viruses in B‐cell malignancies

HemaSphere, Volume 10, Issue 7, July 2026.
Eduard Achim, Guy Ungerechts, Ciprian Tomuleasa, Sabrina Friedel, Michael Hudecek, Cecilia Cristea, Mihaela Tertis, Hermann Einsele   +7 more
wiley   +1 more source