Results 251 to 260 of about 80,643 (282)

A CXCR4 targeting peptide delivered by silica nanoparticles eliminates migrating cancer stem cells in pancreatic ductal adenocarcinoma. [PDF]

Sci Rep
Tiwary K, Lahusen A, Inaas S, Beitzinger B, Schmid R, Harms M, Hauff S, Arnold F, Walter K, Alcala S, Hahn S, Heßmann E, Kleger A, Azoitei N, Seufferlein T, Sainz B, Münch J, Lindén M, Hermann PC.   +18 more
europepmc   +1 more source

Single-Cell Mapping Reveals MIF-Centered Immunoregulatory Networks in Colorectal Cancer. [PDF]

Int J Mol Sci
Gkoris M, Georgakopoulos-Soares I, Zaravinos A.   +2 more
europepmc   +1 more source

POD24 is a novel determinant of prognosis in patients with Waldenström macroglobulinemia. [PDF]

Blood Adv
Zanwar S, Abeykoon J, D'Sa S, Roos-Weil D, Larson DR, Colby CL, Durot E, Kastritis E, Uppal E, Tomkins O, Morel P, Mondello P, Montes L, Paludo J, Ailawadhi S, Sarosiek S, Ogunbiyi O, Cornillet-Lefebvre P, Rajkumar SV, Quinquenel A, Dispenzieri A, Fonseca R, Gertz MA, Kumar S, Dimopoulos MA, Ansell SM, Treon S, Castillo JJ, Kapoor P.   +28 more
europepmc   +1 more source

CXCR4 antagonism corrects neutrophil abnormalities and reduces pneumonia severity in a pharmacological mouse model of CXCR2 loss-of-function-mediated neutropenia. [PDF]

Front Immunol
Nguyen CH, Zmajkovicova K, Sekirnik A, Taplin S, Defontis M, Bledsoe JR, Taveras AG, Karlsson L, Johnson R.   +8 more
europepmc   +1 more source

Reply. [PDF]

J Vasc Surg Venous Lymphat Disord
Fukaya E.
europepmc   +1 more source

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Configurationally Restricted Bismacrocyclic CXCR4 Receptor Antagonists

Journal of Medicinal Chemistry, 2006
A zinc(II) containing configurationally restricted analogue of bismacrocyclic cyclam-type CXCR4 chemokine receptor antagonists has been synthesized and shown to adopt only one configuration in solution. The single crystal X-ray structure reveals favorable binding to acetate via a bidentate chelation that can be related to the proposed interaction with ...
Gina C, Valks, Graeme, McRobbie, Elizabeth A, Lewis, Timothy J, Hubin, Tina M, Hunter, Peter J, Sadler, Christophe, Pannecouque, Erik, De Clercq, Stephen J, Archibald   +8 more
openaire   +2 more sources

Cbl Regulates CXCR4-Mediated Chemotaxis and CXCR4 Receptor Internalization.

Blood, 2004
Abstract CXCL12-induced and CXCR4-mediated chemotaxis plays a critical role in the trafficking of lymphocytes, which modulates inflammatory and immune responses. The CXCR4 receptor is down-modulated by its ligand CXCL12, which has been shown to inhibit HIV entry into the cells.
Ramesh K. Ganju, Aaron Z. Fernandis, Appakkudal R. Anand, Heather C. Lane   +3 more
openaire   +1 more source

Chemokine receptor CXCR4: Role in gastrointestinal cancer

Critical Reviews in Oncology/Hematology, 2013
Chemokines (CK)s, small proinflammatory chemoattractant cytokines that bind to specific G-protein coupled seven-span transmembrane receptors, are major regulators of cell trafficking and adhesion. The CXCL12 [stromal cell-derived factor-1 (SDF-1)] binds primarily to CXC receptor 4 (CXCR4; CD184).
Lombardi L., Tavano F., Morelli F., Latiano T. P., Di Sebastiano P., Maiello E.   +5 more
openaire   +2 more sources