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Expression of chemokine receptor CXCR4 during chick embryo development
Anatomy and Embryology, 2005The chemokine receptor CXCR4 plays a decisive role in physiological cell migration both in developmental processes and adult tissues; it has also been implicated in metastasis formation of different human cancers (Balkwill 2004) and in HIV pathogenesis (Murdoch 2000).
Yusuf, Faisal +3 more
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CXC chemokine ligand 12 (CXCL12) and its receptor CXCR4
Journal of Molecular Medicine, 2014Chemokines were recognized originally for their ability to dictate the migration and activation of leukocytes. However, CXC chemokine ligand 12 (CXCL12, also known as stromal cell-derived factor-1) and its receptor CXCR4 are the first chemokine and receptor that have been shown to be critical for developmental processes, including homing and ...
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Role of chemokine receptors CXCR4 and CXCR7 for platelet function.
Biochemical Society Transactions, 2015Madhumita Chatterjee, D. Rath, M. Gawaz
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[Multiple talents of the chemokine receptor-CXCR4].
Medecine sciences : M/S, 2008CXCR4 is a clinically relevant chemokine receptor that has first gained attention as one of the cofactors for HIV entry into target cells. Moreover, the receptor is involved in cancer cell migration to distant metastatic sites and immune effector recruitment in inflammatory diseases such as asthma and rheumatoid arthritis.
Sonia F, Desjardins +3 more
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Archives of Dermatological Research, 2012
Laura Kühnelt-Leddihn +4 more
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Laura Kühnelt-Leddihn +4 more
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Effect of Chemokine Receptors CXCR4 and CCR7 on the Metastatic Behavior of Human Colorectal Cancer
Clinical Cancer Research, 2005C. Schimanski +9 more
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Involvement of chemokine receptors in breast cancer metastasis
Nature, 2001A. Müller +13 more
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Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
Nature, 1998Y. Zou +4 more
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