Results 11 to 20 of about 1,196,650 (308)

Determination of cytokine profile and associated genes of the signaling pathway in HNSCC [PDF]

, 2022
Head and neck squamose cell carcinoma (HNSCC) is an aggressive group of tumors that are generally heterogeneous. Despite treatment advances, disease-free survival has not significantly improved.
Ozturk, Kayhan, Cora, Tulin, KALAYCI YİĞİN, AYSEL, SEVEN, Mehmet, Azzawri, Ali   +4 more
core   +1 more source

Efficient lysis of rhabdomyosarcoma cells by cytokine-induced killer cells : implications for adoptive immunotherapy after allogeneic stem cell transplantation [PDF]

, 2010
Background: Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and has a poor prognosis. Here we assessed the capability of ex vivo expanded cytokine-induced killer cells to lyse both alveolar and embryonic rhabdomyosarcoma cell lines ...
H. Kreyenberg, Gerrit Weber, S. Kloss, Bader, Peter, Koscielniak, Ewa, A. Willasch, Selim Kuci, T. Klingebiel, E. Koscielniak, Laer, Dorothee von, Miriam Stais, Willasch, Andre Manfred, D. von Laer, Klingebiel, Thomas, Klöß, Stephan, Stais, Miriam, Kuçi, Selim, Peter Bader, Eva Rettinger, Thomas Klingebiel, B. Voss, Z. Kuci, Kreyenberg, Hermann, Stephan Klöss, G. Weber, Dorothee Von Laer, E. Rettinger, Zyrafete Kuci, Kuçi, Zyrafete, Rettinger, Eva, Bernhard Voss, M. Stais, P. Bader, Hermann Kreyenberg, Weber, Gerrit, Voß, Bernhard, Ewa Koscielniak, Andre Willasch, S. Kuci   +38 more
core   +1 more source

Cytokine Receptors-Regulators of Antimycobacterial Immune Response [PDF]

, 2022
Cytokine receptors are critical regulators of the antimycobacterial immune response, playing a key role in initiating and coordinating the recruitment and activation of immune cells during infection.
Godkowicz, Magdalena; https://orcid.org/, Kulesza, Jakub, Wawrocki, Sebastian; https://orcid.org/, Fol, Marek, Druszczyńska, Magdalena; https://orcid.org/   +4 more
core   +1 more source

Evolution of γ chain cytokines: Mechanisms, methods and applications

Computational and Structural Biotechnology Journal, 2022
The common γ chain family of cytokines and their receptors play fundamental roles in the immune system. Evolutionary studies of γ chain cytokines have elegantly illustrated how the immune system adapts to ever-changing environmental conditions.
Magdalena Antczak, Pablo F. Cañete, Zhian Chen, Clémence Belle, Di Yu   +4 more
doaj   +1 more source

Cytokine-induced Src homology 2 protein (CIS) promotes T cell receptor-mediated proliferation and prolongs survival of activated T cells [PDF]

, 2000
Copyright @ 2000 The Rockefeller University Press. This article is shared under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/ and http://creativecommons ...
Sjögren, HO, Paulsson, KM, Anette Sundstedt, Xu, X., Chen, S, Xiufeng Xu, Chen, Shangwu, Sundstedt, Anette, Karlsson, Stefan, Hans-Olov Sjögren, Karlsson, S, Li, Suling, Paulsson, Kajsa, Wang, P, Kajsa M. Paulsson, Sjögren, Hans Olov, Suling Li, Sundstedt, A, Stefan Karlsson, Xu, X, Anderson, P, Ping Wang, Wang, Ping, Shangwu Chen, Per Anderson, andersson, Per, andersson, Per,, Karlsson, Stefan,, Chen, Shangwu,, Li, Suling,, Paulsson, Kajsa,, Xu, X.,, Sjögren, Hans Olov,, Wang, Ping,, Sundstedt, Anette,, Lund University.   +35 more
core   +1 more source

Evolution of Class I cytokine receptors

BMC Evolutionary Biology, 2007
Background The Class I cytokine receptors have a wide range of actions, including a major role in the development and function of immune and blood cells. However, the evolution of the genes encoding them remains poorly understood. To address this we have
Ward Alister C, Liongue Clifford
doaj   +1 more source

Common Ɣ-chain cytokine receptors as functional phenotype markers of PD-1and TIM-3-positive T cells in multiple myeloma

Сибирский онкологический журнал, 2023
T cells expressing checkpoint receptors PD-1, TIM-3 etc., are potential targets for monoclonal antibody immunotherapy in multiple myeloma (MM). However, checkpoint expressing T cell compartment includes different subsets, and their dysregulation ...
E. V. Batorov, V. A. Aristova, G. Yu. Ushakova, S. A. Sizikova, V. V. Denisova, E. Ya. Shevela, A. A. Ostanin, E. R. Chernykh   +7 more
doaj   +1 more source

Fetal-derived trophoblast use the apoptotic cytokine tumor necrosis factor-alpha-related apoptosis-inducing ligand to induce smooth muscle cell death. [PDF]

, 2007
Remodeling of the uterine spiral arteries during pregnancy transforms them from high to low resistance vessels that lack vasoconstrictive properties. This process is essential to meet the demand for increased blood flow imposed by the growing fetus. Loss
Cartwright, JE, Aplin, JD, Whitley, GS, Keogh, RJ, Freeman, A, Harris, LK, Baker, PN   +6 more
core   +1 more source

Cytokine Receptor Endocytosis: New Kinase Activity-Dependent and -Independent Roles of PI3K

Frontiers in Endocrinology, 2017
Type I and II cytokine receptors are cell surface sensors that bind cytokines in the extracellular environment and initiate intracellular signaling to control processes such as hematopoiesis, immune function, and cellular growth and development.
Lily Jun-shen Huang, Ping-hung Chen, Huiyu Yao   +2 more
doaj   +1 more source

Cytokine-induced killer cells for cell therapy of acute myeloid leukemia: improvement of their immune activity by expression of CD33-specific chimeric receptors

Haematologica, 2010
Background Cytokine-induced killer cells are ex vivo-expanded cells with potent antitumor activity. The infusion of cytokine-induced killer cells in patients with acute myeloid leukemia relapsing after allogeneic hematopoietic stem cell transplant is ...
Virna Marin, Irene Pizzitola, Valentina Agostoni, Greta Maria Paola Giordano Attianese, Helene Finney, Alastair Lawson, Martin Pule, Raphael Rousseau, Andrea Biondi, Ettore Biagi   +9 more
doaj   +1 more source