Results 11 to 20 of about 3,641,661 (311)
Microbial Phagocytic Receptors and Their Potential Involvement in Cytokine Induction in Macrophages
Frontiers in Immunology, 2021 Phagocytosis is an essential process for the uptake of large (>0.5 µm) particulate matter including microbes and dying cells. Specialized cells in the body perform phagocytosis which is enabled by cell surface receptors that recognize and bind target ...
Yan Lin Fu +3 more
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Frontiers in Immunology, 2015 Control of cytokine production by immune cells is pivotal for counteracting infections via orchestration of local and systemic inflammation. Although their contribution has long been underexposed, it has recently become clear that human Fc gamma ...
Lisa T C Vogelpoel +3 more
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Structural Basis of IL-1 Family Cytokine Signaling
Frontiers in Immunology, 2019 Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and adaptive immune systems, mediating inflammation in response to a wide range of stimuli.
James K. Fields +6 more
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Flavonoids as Cytokine Modulators: A Possible Therapy for Inflammation-Related Diseases
International Journal of Molecular Sciences, 2016 High levels of cytokines, such as interleukin (IL)-1β, tumor necrosis factor (TNF)-α and IL-6, are associated with chronic diseases like rheumatoid arthritis, asthma, atherosclerosis, Alzheimer’s disease and cancer; therefore cytokine inhibition might be
Nayely Leyva-Lopez +2 more
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Identification of cytokine-induced cell communications by pan-cancer meta-analysis [PDF]
PeerJ, 2023 Cancer immune responses are complex cellular processes in which cytokine–receptor interactions play central roles in cancer development and response to therapy; dysregulated cytokine–receptor communication may lead to pathological processes, including ...
Yining Liu, Min Zhao, Hong Qu
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Structure of the IL-27 quaternary receptor signaling complex
eLife, 2022 Interleukin 27 (IL-27) is a heterodimeric cytokine that functions to constrain T cell-mediated inflammation and plays an important role in immune homeostasis.
Nathanael A Caveney +4 more
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Cells, 2023 Cytokines secreted by individual immune cells regulate tissue regeneration and allow communication between various cell types. Cytokines bind to cognate receptors and trigger the healing process.
Krisztina Nikovics +6 more
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Inflammation and Regeneration, 2022 Recent advances in our understanding in the immune-mediated inflammatory diseases (IMID) are explored and promoted by the targeted treatment. Among these targets, cytokines and cytokine receptors have become the good candidates for the drug development ...
Tsutomu Takeuchi
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Interplay between interleukin-6 signaling and the vascular endothelium in cytokine storms
Experimental and Molecular Medicine, 2021 Interleukin-6 (IL-6) plays a crucial role in host defense against infection and tissue injuries and is a bioindicator of multiple distinct types of cytokine storms.
Sujin Kang, T. Kishimoto
semanticscholar +1 more source
QTY Code-designed Water-soluble Fc-fusion Cytokine Receptors Bind to their Respective Ligands
QRB Discovery, 2020 Cytokine release syndrome (CRS), or ‘cytokine storm’, is the leading side effect during chimeric antigen receptor (CAR)-T therapy that is potentially life-threatening.
Shilei Hao +3 more
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