Results 31 to 40 of about 3,641,661 (311)
Сибирский онкологический журнал, 2023 T cells expressing checkpoint receptors PD-1, TIM-3 etc., are potential targets for monoclonal antibody immunotherapy in multiple myeloma (MM). However, checkpoint expressing T cell compartment includes different subsets, and their dysregulation ...
E. V. Batorov +7 more
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Haematologica, 2010 Background Cytokine-induced killer cells are ex vivo-expanded cells with potent antitumor activity. The infusion of cytokine-induced killer cells in patients with acute myeloid leukemia relapsing after allogeneic hematopoietic stem cell transplant is ...
Virna Marin +9 more
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Soluble cytokine receptors [PDF]
Blood, 1996 HE WORD “HORMONE” comes from the Greek, meaning to set in motion, whereas “humoral” comes from the Latin for ‘‘liquid.’’ Classical hormones are delivered in the blood “to set in motion” target cell proliferation or functional activation. Therefore, humoral specificity depends on the hormone’s ability to interact only with cells expressing the ...
M L, Heaney, D W, Golde
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The molecular details of cytokine signaling via the JAK/STAT pathway
Protein Science, 2018 More than 50 cytokines signal via the JAK/STAT pathway to orchestrate hematopoiesis, induce inflammation and control the immune response. Cytokines are secreted glycoproteins that act as intercellular messengers, inducing proliferation, differentiation ...
Rhiannon Morris, N. Kershaw, J. Babon
semanticscholar +1 more source
Tuning the Cytokine Responses: An Update on Interleukin (IL)-4 and IL-13 Receptor Complexes
Frontiers in Immunology, 2018 Interleukin (IL)-4 and IL-13 are related cytokines that regulate many aspects of allergic inflammation. They play important roles in regulating the responses of lymphocytes, myeloid cells, and non-hematopoietic cells.
I. Junttila
semanticscholar +1 more source
Opioid and nociceptin receptors regulate cytokine and cytokine receptor expression [PDF]
Cellular Immunology, 2008 Opioids were originally discovered because of their ability to induce analgesia, but further investigation has shown that the opioids regulate the function of cells involved in the immune response. We suggest that the regulation of cytokine, chemokine, and cytokine receptor expression is a critical component of the immunomodulatory activity of the ...
M J, Finley +3 more
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Chemokines and Chemokine Receptors: New Targets for Cancer Immunotherapy
Frontiers in Immunology, 2019 Immunotherapy is a clinically validated treatment for many cancers to boost the immune system against tumor growth and dissemination. Several strategies are used to harness immune cells: monoclonal antibodies against tumor antigens, immune checkpoint ...
Valeria Mollica Poeta +3 more
semanticscholar +1 more source
Perspective: Daniela Novick, cytokines and their receptors
Frontiers in Immunology, 2023 This Perspective highlights the work of Dr. Daniela Novick in the field of cytokine biology. Using affinity chromatography to characterize cytokine-binding proteins, she identified soluble forms of the receptors as well as binding proteins for several ...
Pietro Ghezzi +2 more
doaj +1 more source
Interleukin‐13: Targeting an underestimated cytokine in atopic dermatitis
Allergy. European Journal of Allergy and Clinical Immunology, 2019 Atopic dermatitis (AD) is a common inflammatory skin condition that has traditionally been considered a paradigmatic type 2 immunity (T2)‐driven disease.
T. Bieber
semanticscholar +1 more source
Virus encoded cytokines and cytokine receptors
Parasitology, 1997 In order to replicate efficiently within the host, viruses have evolved multiple strategies to evade the host's immune system. In many cases viruses have actually hijacked various components of the host's immune system to ensure their own survival. One such strategy is the expression of virus encoded cytokines and cytokine receptors. Members of
M, Barry, G, McFadden
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