Dietary fatty acids modulate inflammatory cytokine production through activation of MAP kinases [PDF]
Polyunsaturated fatty acids (PUFA) have therapeutic effects in inflammatory diseases, however the specific mechanisms by which they exert these effects have not yet been defined.
Braddish, Della
core +1 more source
Soluble cytokine receptors [PDF]
HE WORD “HORMONE” comes from the Greek, meaning to set in motion, whereas “humoral” comes from the Latin for ‘‘liquid.’’ Classical hormones are delivered in the blood “to set in motion” target cell proliferation or functional activation. Therefore, humoral specificity depends on the hormone’s ability to interact only with cells expressing the ...
M L, Heaney, D W, Golde
openaire +2 more sources
Cytokine Receptors and Their Ligands
Cytokine Receptors and Their ...
D Tvorogov (16025975) +11 more
core +1 more source
Cytokine production and signaling pathways in respiratory virus infection
It has been confirmed that respiratory virus infections can induce abberant cytokine production in the host. These cytokines may be associated with both elimination of the virus and complications in the host, such as virus-induced asthma.
Hirokazu eKimura +4 more
doaj +1 more source
Protein Palmitoylation in Leukocyte Signaling and Function
Palmitoylation is a post-translational modification (PTM) based on thioester-linkage between palmitic acid and the cysteine residue of a protein. This covalent attachment of palmitate is reversibly and dynamically regulated by two opposing sets of ...
Xiaoyuan Yang +5 more
doaj +1 more source
Biosensing Cytokine IL-6: A Comparative Analysis of Natural and Synthetic Receptors
Cytokines are a family of proteins which play a major role in the regulation of the immune system and the development of several diseases, from rheumatoid arthritis to cancer and, more recently, COVID-19.
Eleonora Alfinito +2 more
doaj +1 more source
Alterations in early cytokine-mediated immune responses to Plasmodium falciparum infection in Tanzanian children with mineral element deficiencies: a cross-sectional survey. [PDF]
BACKGROUND: Deficiencies in vitamins and mineral elements are important causes of morbidity in developing countries, possibly because they lead to defective immune responses to infection.
Veenemans, J. +36 more
core +1 more source
Single-chain tandem macrocyclic peptides as a scaffold for growth factor and cytokine mimetics
Peptides composed of two or more tandemly linked macrocyclic peptides binding to growth factor/cytokine receptors (STaMPtides) are useful growth factor/cytokine mimetics.
Kenichiro Ito +8 more
doaj +1 more source
Mechanisms by which interleukin-4 suppresses inflammatory cytokine production by activated human monocytes [PDF]
Improving understanding of how inflammatory responses by monocytes and macrophages are regulated may aid in the development of more targeted therapies for chronic inflammatory disease.
Woodward, Eleanor
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

