Results 81 to 90 of about 584,015 (163)
Understanding the role of P2X7 in affective disorders—are glial cells the major players? [PDF]
, 2015 Pathophysiology associated with several psychiatric disorders has been linked to inflammatory biomarkers. This has generated a theory of major depressive disorders as an inflammatory disease.
Jenkins, Trisha A. +2 more
core +2 more sources
Acute Respiratory Distress Syndrome is a TH17-like and Treg immune disease [PDF]
arXiv, 2013 Acute Respiratory Distress Syndrome (ARDS) is a very severe syndrome leading to respiratory failure and subsequent mortality. Sepsis is one of the leading causes of ARDS. Thus, extracellular bacteria play an important role in the pathophysiology of ARDS. Overactivated neutrophils are the major effector cells in ARDS.
arxiv
Scientific Reports, 2017 Current pathophysiological models of schizophrenia focus on neurodevelopmental and immunological mechanisms. We investigated a molecular pathway traditionally linked to the neurodevelopmental hypothesis (neuregulin 1 - ErbB), and pathogen-associated ...
Szabolcs Kéri +2 more
doaj +1 more source
Shuyi, A Name After Dendritic Cell-mediated Immunological Memory [PDF]
arXiv, 2019 Immunological memory is a fundamental theory of modern immunology, which is traditionally believed to be mediated only by B and T lymphocytes that recognize antigen epitopes in a receptor-restricted manner. During the last decade data accumulated to show that monocytes and macrophages, the two main initiators of innate immune response, also built up a "
arxiv
eLife, 2017 NK cell education is the process through which chronic engagement of inhibitory NK cell receptors by self MHC-I molecules preserves cellular responsiveness. The molecular mechanisms responsible for NK cell education remain unclear.
Antoine Marçais +14 more
doaj +1 more source
Kinetics of cytokine receptor trafficking determine signaling and functional selectivity
eLife, 2019 Cytokines activate signaling via assembly of cell surface receptors, but it is unclear whether modulation of cytokine-receptor binding parameters can modify biological outcomes.
Jonathan Martinez-Fabregas +12 more
doaj +1 more source
Memory NK cell features exploitable in anticancer immunotherapy [PDF]
, 2019 Besides their innate ability to rapidly produce effector cytokines and kill virus-infected or transformed cells, natural killer (NK) cells display a strong capability to adapt to environmental modifications and to differentiate into long-lived ...
Battella, Simone +5 more
core +2 more sources
Beneficial Effects of Gosha-jinki-gan and Green Tea Extract in Rats With Chemical Cystitis
Journal of Pharmacological Sciences, 2013 The aim of this study was to characterize pharmacological effects of gosha-jinki-gan (GJG) and green tea extract (GTE), on urodynamic parameters, bladder receptors, and urinary cytokines in rats with cyclophosphamide (CYP)-induced cystitis.
Sweety Nasrin +3 more
doaj
Tissue signals imprint ILC2 identity with anticipatory function. [PDF]
, 2018 Group 2 innate lymphoid cells (ILC2s) are distributed systemically and produce type 2 cytokines in response to a variety of stimuli, including the epithelial cytokines interleukin (IL)-25, IL-33, and thymic stromal lymphopoietin (TSLP).
Eckalbar, Walter L +10 more
core
A Collaboration Network Model Of Cytokine-Protein Network [PDF]
arXiv, 2007 Complex networks provide us a new view for investigation of immune systems. In this paper we collect data through STRING database and present a model with cooperation network theory. The cytokine-protein network model we consider is constituted by two kinds of nodes, one is immune cytokine types which can act as acts, other one is protein type which ...
arxiv