Results 1 to 10 of about 299,088 (322)
Relationships between renal cytoplasmic and nuclear aldosterone-receptors. [PDF]
Kidney International, 1972 Relationships between renal cytoplasmic and nuclear aldosteronereceptors.Three 3H-aldosterone receptor complexes have been recovered from rat kidneys: 1) cytosol (high speed supernatants), 2) Tris-soluble nuclear (obtained by an osmotic shock procedure),
D. Marver, Daniel B. Goodman, I. Edelman
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Frontiers in Cell and Developmental Biology, 2021 Src-homology-2-containing phosphotyrosine phosphatase (SHP2), a classic cytoplasmic protein and a major regulator of receptor tyrosine kinases and G protein-coupled receptors, plays a significant role in preimplantation embryo development. In this study,
Muhammad Idrees +6 more
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Cellular distribution of estrogen receptors alpha in the rabbit ovary during pregnancy and lactation [PDF]
Scientific ReportsPregnancy and lactation is a critical period for rabbit production. Estrogen (E2) and estrogen receptors alpha (ERA) are essential during pregnancy and lactation and their importance stems from their role in ovarian activities. Despite extensive research
Mahmoud Abd-Elkareem +4 more
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Sex steroid hormone receptors, their ligands, and nuclear and non-nuclear pathways
AIMS Molecular Science, 2015 The ability of a cell to respond to a particular hormone depends on the presence of specific receptors for those hormones. Once the hormone has bound to its receptor, and following structural and biochemical modifications to the receptor, it separates ...
Valentina Contrò +2 more
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The RanGTP pathway: from nucleo-cytoplasmic transport to spindle assembly and beyond
Frontiers in Cell and Developmental Biology, 2016 The small GTPase Ran regulates the interaction of transport receptors with a number of cellular cargo proteins. The high affinity binding of the GTP-bound form of Ran to import receptors promotes cargo release, whereas its binding to export receptors ...
Tommaso eCavazza +4 more
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The Role of Thyroid Hormone in the Regulation of Cerebellar Development [PDF]
Endocrinology and Metabolism, 2021 The proper organized expression of specific genes in time and space is responsible for the organogenesis of the central nervous system including the cerebellum.
Sumiyasu Ishii +2 more
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The Ebola Virus Interferon Antagonist VP24 Undergoes Active Nucleocytoplasmic Trafficking
Viruses, 2021 Viral interferon (IFN) antagonist proteins mediate evasion of IFN-mediated innate immunity and are often multifunctional, with distinct roles in viral replication.
Angela R. Harrison +3 more
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Stimulus-dependent regulation of nuclear Ca2+ signaling in cardiomyocytes: a role of neuronal calcium sensor-1. [PDF]
PLoS ONE, 2015 In cardiomyocytes, intracellular calcium (Ca2+) transients are elicited by electrical and receptor stimulations, leading to muscle contraction and gene expression, respectively.
Shu Nakao +2 more
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Transcriptional Regulation of Pyruvate Dehydrogenase Kinase [PDF]
Diabetes & Metabolism Journal, 2012 The pyruvate dehydrogenase complex (PDC) activity is crucial to maintains blood glucose and ATP levels, which largely depends on the phosphorylation status by pyruvate dehydrogenase kinase (PDK) isoenzymes.
Ji Yun Jeong +3 more
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PLoS Pathogens, 2010 An important layer of plant innate immunity to host-adapted pathogens is conferred by intracellular nucleotide-binding/oligomerization domain-leucine rich repeat (NB-LRR) receptors recognizing specific microbial effectors.
Ana V García +7 more
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