Results 1 to 10 of about 268,012 (165)

ZBED4, a cone and Müller cell protein in human retina, has a different cellular expression in mouse. [PDF]

open access: yes, 2011
PurposeZBED4, a protein in cones and Müller cells of human retina, may play important functions as a transcriptional activator of genes expressed in those cells or as a co-activator/repressor of their nuclear hormone receptors.
Akhmedov, Novrouz B   +3 more
core   +1 more source

Mast cell clones: a model for the analysis of cellular maturation. [PDF]

open access: yes, 1982
Cloned mouse mast cells resemble, by ultrastructure, immature mast cells observed in vivo. These mast cell clones can be grown in the absence of any other cells, facilitating direct investigations of their biochemistry and function.
Cantor, H   +10 more
core   +2 more sources

The nuclear-cytoplasmic trafficking of a chromatin-modifyng and remodelling protein (KMT2C), in osteosarcoma [PDF]

open access: yes, 2018
Osteosarcoma is the most common paediatric primary non-hematopoietic bone tumor; the survival is related to the response to chemotherapy and development of metastases.
Carletti, Raffaella   +5 more
core   +1 more source

Porcine oocyte maturation in vitro : role of cAMP and oocyte-secreted factors: a practical approach [PDF]

open access: yes, 2016
Polyspermy or the penetration of more than one sperm cell remains a problem during porcine in vitro fertilization (IVF). After in vitro culture of porcine zygotes, only a low percentage of blastocysts develop and their quality is inferior to that of in ...
Appeltant, Ruth   +4 more
core   +2 more sources

Nuclear Translocation of the p75 Neurotrophin Receptor Cytoplasmic Domain in Response to Neurotrophin Binding [PDF]

open access: yesThe Journal of Neuroscience, 2005
The intracellular domain of the p75 neurotrophin receptor (p75ICD) can be released by γ-secretase in response to the previous activation of α-secretase by phorbol esters. However, ligand-dependent release of p75ICDhas yet to be described. We show here that nerve growth factor can induce the release of p75ICDand facilitate its translocation to the ...
openaire   +4 more sources

Embryonic and post-embryonic utilization and subcellular localization of the nuclear receptor SpSHR2 in the sea urchin [PDF]

open access: yes, 1998
SpSHR2 (Strongylocentrotus purpuratus steroid hormone receptor 2) is a nuclear receptor, encoded by a maternal RNA in the sea urchin embryo. These maternal SpSHR2 transcripts, which are present in all cells, persist until the blastula stage and then are ...
Flytzanis, Constantin N.   +2 more
core  

Cytoplasmic and nuclear testosterone receptors in the hypothalamus of androgenized female and castrated male rats

open access: yesNeuroscience and Behavioral Physiology, 1985
Receptors for testosterone (T) in the preopticoanterior hypothalamus (PO) and in the arcuate nucleus and median eminence (ARC + ME) were examined in neonatally androgenized female and neonatally castrated male rats. As a result of neonatal castration of males, the concentration of cytoplasmic and nuclear receptors for T in the PO dropped to an ...
V. I. Babichev   +2 more
openaire   +4 more sources

Control of steroid receptor function and cytoplasmic‐nuclear transport by heat shock proteins [PDF]

open access: yesBioEssays, 1992
AbstractAs targeted proteins that move within the cell, the steroid receptors have become very useful probes for understanding the linked phenomena of protein folding and transport. From the study of steroid receptor‐associated proteins it has become clear over the past two years that these receptors are bound to a multiprotein complex containing at ...
openaire   +4 more sources

γδ T cells affect IL-4 production and B-cell tolerance [PDF]

open access: yes, 2014
γδ T cells can influence specific antibody responses. Here, we report that mice deficient in individual γδ T-cell subsets have altered levels of serum antibodies, including all major subclasses, sometimes regardless of the presence of αβ T cells.
Andrew Getahun   +22 more
core   +1 more source

Nanoscale stiffness topography reveals structure and mechanics of the transport barrier in intact nuclear pore complexes [PDF]

open access: yes, 2014
The nuclear pore complex (NPC) is the gate for transport between the cell nucleus and the cytoplasm. Small molecules cross the NPC by passive diffusion, but molecules larger than ∼5 nm must bind to nuclear transport receptors to overcome a selective ...
A Goryaynov   +39 more
core   +1 more source

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