Results 11 to 20 of about 186,066 (336)
Relationships between renal cytoplasmic and nuclear aldosterone-receptors. [PDF]
Kidney International, 1972 Relationships between renal cytoplasmic and nuclear aldosteronereceptors.Three 3 H-aldosterone receptor complexes have been recovered from rat kidneys: 1) cytosol (high speed supernatants), 2) Tris-soluble nuclear (obtained by an osmotic shock procedure),
D. Marver, Daniel B. Goodman, I. Edelman
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Frontiers in Cell and Developmental Biology, 2021 Src-homology-2-containing phosphotyrosine phosphatase (SHP2), a classic cytoplasmic protein and a major regulator of receptor tyrosine kinases and G protein-coupled receptors, plays a significant role in preimplantation embryo development. In this study,
Muhammad Idrees +6 more
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Balanced nuclear and cytoplasmic activities of EDS1 are required for a complete plant innate immune response. [PDF]
PLoS Pathogens, 2010 An important layer of plant innate immunity to host-adapted pathogens is conferred by intracellular nucleotide-binding/oligomerization domain-leucine rich repeat (NB-LRR) receptors recognizing specific microbial effectors.
Ana V García +7 more
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Cytoplasmic versus nuclear THR alpha expression determines survival of ovarian cancer patients [PDF]
Journal of Cancer Research and Clinical Oncology, 2020 Purpose Thyroid hormone receptors (THR) have manifold functions and are involved in the carcinogenesis of several tumor types. Within this study, we aimed to investigate the expression pattern (nuclear versus cytoplasmic) of the THR alpha and its impact ...
N. Ditsch +11 more
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An association of a simultaneous nuclear and cytoplasmic localization of Fra-1 with breast malignancy [PDF]
BMC Cancer, 2006 Background Overexpression of Fra-1 in fibroblasts causes anchorage-independent cell growth and oncogenic transformation. A high level of Fra-1 expression is found in various tumors and tumorigenic cell lines, suggesting that Fra-1 may be involved in ...
Chen Liyong +9 more
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Nuclear Cytoplasmic Shuttling by Thyroid Hormone Receptors [PDF]
Journal of Biological Chemistry, 2001 In this report, we have studied the intracellular dynamics and distribution of the thyroid hormone receptor-β (TRβ) in living cells, utilizing fusions to the green fluorescent protein.
Christopher T. Baumann +3 more
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Regulating Phase Transition in Neurodegenerative Diseases by Nuclear Import Receptors [PDF]
Biology, 2022 RNA-binding proteins (RBPs) with a low-complexity prion-like domain (PLD) can undergo aberrant phase transitions and have been implicated in neurodegenerative diseases such as ALS and FTD.
Amandeep Girdhar, Lin Guo
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A new procedure for the quantitation of nuclear and cytoplasmic androgen receptors.
Journal of Biological Chemistry, 1981 Experimental conditions for the measurement of prostatic androgen receptors occupied with unlabeled hormone are described. The assay allows quantitation of cytoplasmic and nuclear receptors occupied with unlabeled ligand by exchange with 17 beta-hydroxy ...
A. Traish, R. Muller, H. Wotiz
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Estrogen‐Mediated Cytoplasmic and Nuclear Distribution of Rat Cardiovascular Estrogen Receptors
Arteriosclerosis, 1985 We used either the synthetic estrogen R2858 (moxestrol) or estradiol-17 beta to characterize estrogen receptors in cytoplasmic (R2858) and nuclear (estradiol-17 beta) preparations from rat aorta and myocardium. Relative steroid specificity studies showed
A. L. Lin, S. Shain
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Arteriosclerosis, 1985 We used either the synthetic androgen R1881 (methyltrienolone) or 5 alpha-dihydrotestosterone (5 alpha-DHT) to characterize androgen receptors in rat aortic and myocardial cytoplasmic and nuclear preparations.
A. L. Lin, R. González, S. Shain
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