Nuclear and cytoplasmic oestrogen receptors in squamous carcinoma of the cervix. [PDF]
British Journal of Cancer, 1981 Nuclear and cytoplasmic oestrogen receptors (REN and REC) were sought in 5 normal cervices and in 43 specimens of squamous carcinoma of the cervix. All 3 tissues components of the 5 normal cervices contained both REN and REC.
W. P. Soutter +5 more
semanticscholar +3 more sources
Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization [PDF]
Reproductive Biology and Endocrinology, 2008 BackgroundGranulosa cells play an important endocrine role in folliculogenesis. They mobilize Ca2+ from intracellular stores by a coordinated action between 1,4,5 inositol trisphosphate and ryanodine receptors (IP3R and RyR). The aim of this study was to
M. Díaz-Muñoz +4 more
semanticscholar +4 more sources
Estrogen‐Mediated Cytoplasmic and Nuclear Distribution of Rat Cardiovascular Estrogen Receptors [PDF]
Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1985 We used either the synthetic estrogen R2858 (moxestrol) or estradiol-17 beta to characterize estrogen receptors in cytoplasmic (R2858) and nuclear (estradiol-17 beta) preparations from rat aorta and myocardium. Relative steroid specificity studies showed that only estrogens were effective inhibitors of R2858 or estradiol-17 beta binding to aortic and ...
A. L. Lin, S. Shain
semanticscholar +3 more sources
Quantitative estimates of cytoplasmic and nuclear oestrogen receptors in chick oviduct. Effect of oestrogen on receptor concentration and subcellular distribution. [PDF]
European Journal of Biochemistry, 1976 [3H]Oestradiol exchange techniques were developed for the determination of specific cestrogen receptor site concentrations in the cytoplasm and nuclei of chick oviduct cells. Non‐labelled receptor‐bound oestrogens were exchanged with [3H]oestradiol during a 24‐h incubation at 20 °C. 2 h at 30 °C or 45 min at 37 °C.
R. Sutherland, E. Baulieu
semanticscholar +3 more sources
Nucleocytoplasmic Communication in Healthy and Diseased Plant Tissues
Frontiers in Plant Science, 2021 The double membrane of the nuclear envelope (NE) constitutes a selective compartment barrier that separates nuclear from cytoplasmic processes. Plant viability and responses to a changing environment depend on the spatial communication between both ...
Daniel Lüdke +3 more
doaj +1 more source
An agent-based model for mRNA export through the nuclear pore complex. [PDF]
, 2014 mRNA export from the nucleus is an essential step in the expression of every protein- coding gene in eukaryotes, but many aspects of this process remain poorly understood.
Azimi, Mohammad +3 more
core +2 more sources
Frontiers in Cell and Developmental Biology, 2021 RationaleGq-coupled receptors are thought to play a critical role in the induction of left ventricular hypertrophy (LVH) secondary to pressure overload, although mechano-sensitive channel activation by a variety of mechanisms has also been proposed, and ...
Ze-Yan Yu +17 more
doaj +1 more source
Expression in the human brain of retinoic acid induced 1, a protein associated with neurobehavioural disorders [PDF]
, 2014 Acknowledgements Funding was provided by the Wellcome Trust and Tenovus Scotland. Prof Fragoso is the recipient of a Post Doctoral Science without Borders grant from the Brazilian National Council for Scientific and Technological Development (CNPq, 37450/
Fragoso, Yara Dadalti +6 more
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BMC Cancer, 2018 Background In ovarian cancer, the role of estrogen receptors (ERs), particularly of ERβ, being suggested as tumor suppressor in breast and prostate cancer, remains unclear.
Susanne Schüler-Toprak +4 more
doaj +1 more source
The human gonadotropin releasing hormone type I receptor is a functional intracellular GPCR expressed on the nuclear membrane. [PDF]
PLoS ONE, 2010 The mammalian type I gonadotropin releasing hormone receptor (GnRH-R) is a structurally unique G protein-coupled receptor (GPCR) that lacks cytoplasmic tail sequences and displays inefficient plasma membrane expression (PME).
Michelle Re +9 more
doaj +1 more source