Results 11 to 20 of about 268,012 (165)

Relationships between renal cytoplasmic and nuclear aldosterone-receptors [PDF]

Kidney International, 1972
Relationships between renal cytoplasmic and nuclear aldosteronereceptors.Three 3H-aldosterone receptor complexes have been recovered from rat kidneys: 1) cytosol (high speed supernatants), 2) Tris-soluble nuclear (obtained by an osmotic shock procedure),
Aldo Jongejan (793996), Antoine H. C. van Kampen (820449), Hans van der Spek (55162), Josephine M. E. Tan (4568137), Martijs J. Jonker (125464), Reuben L. Smith (4568143), Stanley Brul (394155), Steve Veldhuijzen (4568140), Thomas Buissink (4568146)   +8 more
core   +16 more sources

Nuclear and cytoplasmic oestrogen receptors in squamous carcinoma of the cervix [PDF]

British Journal of Cancer, 1981
Nuclear and cytoplasmic oestrogen receptors (REN and REC) were sought in 5 normal cervices and in 43 specimens of squamous carcinoma of the cervix. All 3 tissues components of the 5 normal cervices contained both REN and REC. Thirty-five (81%) of the tumours contained receptors, but in only 9 (21%) were they found in both subcellular compartments ...
R. W. Green-Thompson, R J Pegoraro, D V Naidoo, Septimus M. Joubert, R H Philpott, W P Soutter   +5 more
openaire   +3 more sources

An agent-based model for mRNA export through the nuclear pore complex. [PDF]

, 2014
mRNA export from the nucleus is an essential step in the expression of every protein- coding gene in eukaryotes, but many aspects of this process remain poorly understood.
Azimi, Mohammad, Bulat, Evgeny, Mofrad, Mohammad RK, Weis, Karsten   +3 more
core   +2 more sources

Narrative-based computational modelling of the Gp130/JAK/STAT signalling pathway. [PDF]

, 2008
BACKGROUND: Appropriately formulated quantitative computational models can support researchers in understanding the dynamic behaviour of biological pathways and support hypothesis formulation and selection by "in silico" experimentation.
A Herrmann, A Mahdavi, A Regev, A Regev, A Singh, A Verma, AD Sharrocks, Anna Dudka, B Alberts, C Priami, C Priami, Corrado Priami, D Gillespie, F Ciocchetta, I Lödige, I Swameye, J Bravo, J Fisher, J Heath, J ten Hoeve, John K Heath, K Rakesh, L Dematté, L Dematté, L Klampfer, M Calder, M Kwiatkowska, Maria Luisa Guerriero, ML Guerriero, ML Guerriero, ML Guerriero, N Underhill-Day, NC Reich, Nicholas Underhill-Day, P Heinrich, S Bhattacharya, T Yamamoto, WS Alexander   +37 more
core   +6 more sources

Expression in the human brain of retinoic acid induced 1, a protein associated with neurobehavioural disorders [PDF]

, 2014
Acknowledgements Funding was provided by the Wellcome Trust and Tenovus Scotland. Prof Fragoso is the recipient of a Post Doctoral Science without Borders grant from the Brazilian National Council for Scientific and Technological Development (CNPq, 37450/
Fragoso, Yara Dadalti, McCaffery, Peter, Nanescu, Sonia E., Sementilli, Angelo, Sementilli, Pietro, Shearer, Kirsty D., Stoney, Patrick N.   +6 more
core   +2 more sources

Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons. [PDF]

, 2015
Previous studies have revealed a critical role for CREB-regulated transcriptional coactivator (CRTC1) in regulating neuronal gene expression during learning and memory. CRTC1 localizes to synapses but undergoes activity-dependent nuclear translocation to
Ch'ng, Toh Hean, DeSalvo, Martina, Lin, Peter, Martin, Kelsey C, Vashisht, Ajay, Wohlschlegel, James A   +5 more
core   +1 more source

Nuclear Cytoplasmic Shuttling by Thyroid Hormone Receptors [PDF]

Journal of Biological Chemistry, 2001
In this report, we have studied the intracellular dynamics and distribution of the thyroid hormone receptor-beta (TRbeta) in living cells, utilizing fusions to the green fluorescent protein. Wild-type TRbeta was mostly nuclear in both the absence and presence of triiodothyronine; however, triiodothyronine induced a nuclear reorganization of TRbeta.
Padma Maruvada, Paul M. Yen, Gordon L. Hager, Christopher T. Baumann   +3 more
openaire   +3 more sources

A monopartite nuclear localization sequence regulates nuclear targeting of the actin binding protein myopodin [PDF]

, 2005
Myopodin is an actin bundling protein that shuttles between nucleus and cytoplasm in response to cell stress or during differentiation. Here, we show that the myopodin sequence (58)KKRRRRARK(66), when tagged to either enhanced green fluorescent protein ...
De Corte, Veerle, De Ganck, Ariane, Geelen, Danny, Gettemans, Jan, Hubert, Thomas, Van Impe, Katrien, Vandekerckhove, Joël   +6 more
core   +1 more source

Sequences within the C terminus of the metabotropic glutamate receptor 5 (mGluR5) are responsible for inner nuclear membrane localization [PDF]

, 2017
Traditionally, G-protein-coupled receptors (GPCR) are thought to be located on the cell surface where they transmit extracellular signals to the cytoplasm.
Harmon, Steven K., Jong, Yuh-Jiin I., Kumar, Vikas, O\u27Malley, Karen L., Sergin, Ismail   +4 more
core   +2 more sources

A new procedure for the quantitation of nuclear and cytoplasmic androgen receptors.

Journal of Biological Chemistry, 1981
Experimental conditions for the measurement of prostatic androgen receptors occupied with unlabeled hormone are described. The assay allows quantitation of cytoplasmic and nuclear receptors occupied with unlabeled ligand by exchange with 17 beta-hydroxy-17 alpha-methyl [3H]estra-4,9,11-trien-3-one at 0 degrees C.
Herbert H. Wotiz, R E Müller, Abdulmaged M. Traish   +2 more
openaire   +3 more sources