Results 261 to 270 of about 285,475 (309)

Cytoplasmic and Nuclear Estradiol and Progesterone Receptors in Human Endometrium*

The Journal of Clinical Endocrinology & Metabolism, 1978
Estradiol and progesterone receptors have been characterized in normal human endometrial biopsy samples. The cytosol and nuclei were prepared from 150-250-mg samples, either processed immediately or kept in liquid nitrogen. The total concentration of estradiol-and progesterone-binding sites (available or occupied with endogenous hormone) were measured ...
F, Bayard, S, Damilano, P, Robel, E E, Baulieu   +3 more
openaire   +2 more sources

Ecdysteroid Receptors: A Comparison of Cytoplasmic and Nuclear Receptors from Crayfish Hypodermis

Hoppe-Seyler´s Zeitschrift für physiologische Chemie, 1982
Cytoplasmic and nuclear ecdysteroid receptors from intermolt Orconectes limosus integument have been compared. The specificities as well as the KD values for three [3H]ecdysteroids are very similar in both preparations. Using a photoaffinity labelling technique, the molecular mass of the hormone-receptor complexes from both preparations was determined ...
M, Londershausen, P, Kuppert, K D, Spindler   +2 more
openaire   +2 more sources

Nuclear and cytoplasmic receptors for 1,25-dihydroxycholecalciferol in intestinal mucosa

Biochemical and Biophysical Research Communications, 1973
The apparent hormonal form of cholecalciferol, 1,25-dihydroxycholecalciferol (1,25-(OH)2-CC), was incubated with intestinal mucosa homogenates and whole intestinal tissue, in vitro. After 40–70 min, 1,25-(OH)2-CC was specifically associated with the nuclear chromatin fraction.
P F, Brumbaugh, M R, Haussler
openaire   +2 more sources

Nuclear and cytoplasmic lectin receptor sites in rat Py1a osteoblasts.

Histology and histopathology, 2000
The intracellular distribution of lectin receptor sites was studied in the rat Pyla osteoblasts using immunofluorescence at the confocal microscopy level. This immortalized cell line was found to represent a satisfactory model to study the occurrence and distribution of sugar moieties.
SABBIETI, Maria Giovanna, MARCHETTI, Luigi, HURLEY M. M., MENGHI G.   +3 more
openaire   +3 more sources

Cytoplasmic and Nuclear Cytokine Receptor Complexes

1997
Much of our understanding on how hormones and cytokines transmit their message into the cell is based on the receptor activation at the plasma membrane. Many experimental in vitro models have established the paradigm for cytokine action based upon such activation of their cell surface receptor.
H C, Mertani, G, Morel, P E, Lobie
openaire   +2 more sources

Cytoplasmic and nuclear signaling pathways of V1-vascular vasopressin receptors

Regulatory Peptides, 1993
We studied the cytoplasmic and nuclear signaling pathways of V1-vascular AVP receptors of human platelets, primary cultures of renal glomerular mesangial cells, and established cultures of the A7r5 aortic smooth muscle cell line. The immediate transmembrane signals are triggered by the formation of ligand-receptor complexes as illustrated by binding ...
M, Thibonnier, A L, Bayer, Z, Leng
openaire   +2 more sources

Are estrogen receptors cytoplasmic or nuclear? Some immunocytochemical and biochemical studies

Journal of Steroid Biochemistry, 1987
The subcellular localization of estradiol receptor (ER) has been examined using various experimental approaches. Immunocytochemical studies using the monoclonal antibody JS 34/32, raised against calf uterine cytosolic ER, yielded only equivocal results. In general, cells and tissues pretreated with estradiol showed positive immunostaining in the nuclei
I, Parikh, K G, Rajendran, J L, Su, T, Lopez, M, Sar   +4 more
openaire   +2 more sources

Characteristics of Cytoplasmic and Nuclear Receptor Forms

1979
Although this monograph is primarily concerned with the relationship between hormone-induced responses and nuclear binding, it is necessary to relate nuclear receptors to their cytoplasmic counterparts.
James H. Clark, Ernest J. Peck
openaire   +1 more source

Characteristics of the cytoplasmic and nuclear dihydrotestosterone receptors of human thymic tissue

Steroids, 1983
Dihydrotestosterone receptor was prepared from both the cytoplasm and nucleus of human thymic tissue. Human cytoplasmic and nuclear dihydrotestosterone receptor possessed a KA greater than 1.0 and by competition assay was highly specific for dihydrotestosterone.
C J, Grossman, L J, Sholiton, J A, Helmsworth   +2 more
openaire   +2 more sources

Nuclear‐cytoplasmic transport of EGFR involves receptor endocytosis, importin β1 and CRM1

Journal of Cellular Biochemistry, 2006
AbstractMany receptor tyrosine kinases (RTKs) can be detected in the cell nucleus, such as EGFR, HER‐2, HER‐3, HER‐4, and fibroblast growth factor receptor. EGFR, HER‐2 and HER‐4 contain transactivational activity and function as transcription co‐factors to activate gene promoters. High EGFR in tumor nuclei correlates with increased tumor proliferation
Hui-Wen, Lo, Mohamed, Ali-Seyed, Yadi, Wu, Geoffrey, Bartholomeusz, Sheng-Chieh, Hsu, Mien-Chie, Hung   +5 more
openaire   +2 more sources