EFFECT OF ERYTHROPOIETIN ON CYTOKINE PRODUCTION BY STEM CELLS
Медицинская иммунология, 2019 Erythropoietin (EPO) is mainly used to stimulate erythropoiesis. Its cytoprotective effects upon other cells of the human body and animals were recently shown, in particular, anti-apoptotic effect was observed.
A. P. Lykov +6 more
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Tubular Erythropoietin Receptor Expression Mediates Erythropoietin-Induced Renoprotection [PDF]
The Open Hematology Journal, 2009 Erythropoietin (EPO) has been shown to have tissue protective properties by binding to its receptor (EPOR) which is also expressed on non-haematopoietic cells. The mechanisms underlying this protection have not yet been eluci- dated and the renal cell types mediating these effects remain ill-defined.
De Beuf, Annelies +6 more
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Pharmacological targeting of the ephrin receptor kinase signalling by GLPG1790 in vitro and in vivo reverts oncophenotype, induces myogenic differentiation and radiosensitizes embryonal rhabdomyosarcoma cells [PDF]
, 2017 EPH (erythropoietin-producing hepatocellular) receptors are clinically relevant targets in several malignancies. This report describes the effects of GLPG1790, a new potent pan-EPH inhibitor, in human embryonal rhabdomyosarcoma (ERMS) cell ...
Beirinckx, Filip +20 more
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Second-generation non-hematopoietic erythropoietin-derived peptide for neuroprotection
Redox Biology, 2022 Erythropoietin (EPO) is a well-known erythropoietic cytokine having a tissue-protective effect in various tissues against hypoxic stress, including the brain. Thus, its recombinants may function as neuroprotective compounds. However, despite considerable
Bongki Cho +6 more
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Erythropoietin receptor and hematological disease [PDF]
American Journal of Hematology, 1999 This review will discuss evidence for the role of the erythropoietin (Epo) receptor in the development of erythrocytosis and other hematological disorders. The possible causative role of mutations of other genes in the pathogenesis of idiopathic erythrocytosis will be considered. Polycythemia vera (PV) is a myeloproliferative disorder that is caused by
McMullin, Mary Frances, Percy, M.J.
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Signalling mechanisms of long term facilitation of breathing with intermittent hypoxia. [PDF]
, 2013 Intermittent hypoxia causes long-term facilitation (LTF) of respiratory motor nerve activity and ventilation, which manifests as a persistent increase over the normoxic baseline for an hour or more after the acute hypoxic ventilatory response.
Pamenter, Matthew E, Powell, Frank L
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Symmetric signaling by an asymmetric 1 erythropoietin : 2 erythropoietin receptor complex [PDF]
, 2008 Thesis (M. Eng.)--Massachusetts Institute of Technology, Biological Engineering Division, 2008.Includes bibliographical references (p. 43-46).One erythropoietin molecule binds asymmetrically to two identical receptor monomers via erythropoietin site 1 ...
Zhang, Yingxin
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Macrophages as novel target cells for erythropoietin
Haematologica, 2010 Background Our original demonstration of immunomodulatory effects of erythropoietin in multiple myeloma led us to the search for the cells in the immune system that are direct targets for erythropoietin.
Lilach Lifshitz +4 more
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Heart Views, 2021 Heart failure (HF) remains one of the most common diseases and one of the major causes of death worldwide. HF is often associated with other chronic diseases, most commonly with anemia.
Neda Jonaitiene +2 more
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Possible erythropoietin pharmacotherapeutic targets on painful diabetic neuropathy in rats [PDF]
Anais da Academia Brasileira de CiênciasErythropoietin is a renal cytokine involved in regulating hematopoiesis. Current evidence indicates that erythropoietin exerts pleiotropic effects in animal models.
SAMUEL SUAREZ-MENDEZ +1 more
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