Results 41 to 50 of about 577,108 (265)

Erythropoietin: a new perspective in cardiovascular therapy

Monaldi Archives for Chest Disease, 2016
Erythropoietin is a hormone produced by the kidney, which regulates proliferation, differentiation and maturation of red cells. Recombinant human EPO (rH-EPO) is well known to correct anaemia in patients with chronic renal failure in terminal stage ...
Riccardo Raddino, Debora Robba, Giorgio Caretta, Ivano Bonadei, Melissa Teli, Gregoriana Zanini, Alberto Madureri, Enrico Vizzardi, Livio Dei Cas   +8 more
doaj   +1 more source

Triggering of erythropoietin production by hypoxia is inhibited by respiratory and metabolic acidosis [PDF]

, 1990
Erythropoietin (EPO) production in response to hypoxic hypoxia is known to be attenuated by simultaneous hypercapnia. This study aimed to investigate whether this inhibitory effect of hypercapnia is 1) a direct effect of carbon dioxide or mediated by ...
Eckardt, K. U., Kurtz, Armin, Bauer, C., A. Kurtz, C. Bauer, K. U. Eckardt   +5 more
core   +1 more source

Erythropoietin Protects the Kidney by Regulating the Effect of TNF-α in L-NAME-Induced Hypertensive Rats

Kidney & Blood Pressure Research, 2018
Background/Aims: Hypertension is the leading cause of death worldwide. Chronic high blood pressure induces inflammation. Tumor necrosis factor (TNF)-α plays a major role in inflammation and also depresses the synthesis of erythropoietin, which exerts ...
Mete Ozkurt, Kubilay Uzuner, Nilufer Erkasap, Gokhan Kus, Rumeysa Ozyurt, Onur Uysal, Ibrahim Akyazi, Ozden Kutlay   +7 more
doaj   +1 more source

Haemoglobin mass and running time trial performance after recombinant human erythropoietin administration in trained men [PDF]

, 2013
<p>Recombinant human erythropoietin (rHuEpo) increases haemoglobin mass (Hbmass) and maximal oxygen uptake (v˙ O2 max).</p> <p>Purpose: This study defined the time course of changes in Hbmass, v˙ O2 max as well as running time trial ...
Wondimu, D.H., Chatterji Tushar, McClure, J.D., Padmanabhan Neal, Daskalaki Evangelia, Anderson Martin, Patel Rajan K., Wondimu, Diresibachew H., Jérôme Durussel, Anderson, Martin, Tushar Chatterji, John D McClure, Patel, Rajan K., Pitsiladis, Yannis P., Pitsiladis, Yannis; id_orcid, Chatterji, Tushar, Martin Anderson, Rajan K Patel, Evangelia Daskalaki, Yannis P Pitsiladis, Pitsiladis Yannis P., Neal Padmanabhan, McClure John D., Padmanabhan, Neal, Anderson, M., Pitsiladis, Y.P., Daskalaki, Evangelia, Durussel, Jérôme, Daskalaki, E., Chatterji, T., Padmanabhan, N., Durussel, J., Diresibachew H Wondimu, McClure, John D., Patel, R.K., Durussel Jérôme, Wondimu Diresibachew H.   +36 more
core   +2 more sources

Serum erythropoietin and erythropoiesis in primary and secondary hyperparathyroidism: effect of parathyroidectomy [PDF]

, 1991
Primary as well as secondary hyperparathyroidism may be associated with anemia, and parathyroidectomy (PTx) may improve or even heal it. The precise link between the two conditions is still matter of discussion.
Zins, B., Roullet, J. B., Kurtz, Armin, Sarfati, E., Zingraff, J., Ureña, P., Eckardt, Kai-Uwe, Drüeke, T., Roland, E.   +8 more
core   +1 more source

Targeted Delivery of Erythropoietin Hybridized with Magnetic Nanocarriers for the Treatment of Central Nervous System Injury: A Literature Review

International Journal of Nanomedicine, 2020
Chang Ho Hwang Department of Physical and Rehabilitation Medicine, Chungnam National University Sejong Hospital, Chungnam National University College of Medicine, Sejong, Republic of KoreaCorrespondence: Chang Ho HwangDepartment of Physical and ...
Hwang CH
doaj  

The Orphan Cytokine Receptor CRLF3 Emerged With the Origin of the Nervous System and Is a Neuroprotective Erythropoietin Receptor in Locusts

Frontiers in Molecular Neuroscience, 2019
The orphan cytokine receptor-like factor 3 (CRLF3) was identified as a neuroprotective erythropoietin receptor in locust neurons and emerged with the evolution of the eumetazoan nervous system.
Nina Hahn, Luca Büschgens, Nicola Schwedhelm-Domeyer, Sarah Bank, Bart R. H. Geurten, Pia Neugebauer, Bita Massih, Martin C. Göpfert, Ralf Heinrich   +8 more
doaj   +1 more source

Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway [PDF]

, 2003
Objective. Erythropoietin (EPO) is a key regulator of erythropoiesis, playing a role in both the proliferation and differentiation of erythroid cells.
Eggen, BJL, Vellenga, E, Vellenga, Edo,, Vogelzang, Irma, Eggen, BJL; id_orcid, Vogelzang, Irma,, Wierenga, Albertus T.J., Wierenga, Albertus T.J.,, Eggen, Bart J.L.,   +8 more
core   +1 more source

Recent advances of the Ephrin and Eph family in cardiovascular development and pathologies

iScience
Summary: Erythropoietin-producing hepatoma (Eph) receptors, comprising the largest family of receptor tyrosine kinases (RTKs), exert profound influence on diverse biological processes and pathological conditions such as cancer.
Yuan Zhu, Sheng-an Su, Jian Shen, Hong Ma, Jixie Le, Yao Xie, Meixiang Xiang   +6 more
doaj   +1 more source

Association between high-dose erythropoiesis-stimulating agents, inflammatory biomarkers, and soluble erythropoietin receptors

BMC Nephrology, 2011
Background High-dose erythropoiesis-stimulating agents (ESA) for anemia of chronic kidney disease (CKD) have been associated with adverse clinical outcomes and do not always improve erythropoiesis.
Inrig Jula K, Bryskin Suzanne K, Patel Uptal D, Arcasoy Murat, Szczech Lynda A   +4 more
doaj   +1 more source