Results 21 to 30 of about 19,757 (238)

A critical role for erythropoietin on vagus nerve Schwann cells in intestinal motility

BMC Biotechnology, 2023
Background Dysmotility and postoperative ileus (POI) are frequent major clinical problems post-abdominal surgery. Erythropoietin (EPO) is a multifunctional tissue-protective cytokine that promotes recovery of the intestine in various injury models. While
Prem Kumar Govindappa, Mosammat Begom, Yash Gupta, John C. Elfar, Manmeet Rawat, Walaa Elfar   +5 more
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Localization of Erythropoietin and Erythropoietin‐Receptor in Postimplantation Mouse Embryos [PDF]

Development, Growth & Differentiation, 1993
We used RT‐PCR (reverse transcription‐polymerase chain reaction) and immunocytochemical methods to demonstrate the presence of erythropoietin (Ep) and its receptor (EpR) in postimplantation mouse embryos from the egg‐cylinder to the unturned stage. Expression of mRNA for EpR was detected in total RNA from embryos and decidua in all these stages, but Ep
Yoshiko, Yasuda, Masaya, Nagao, Masaki, Okano, Seiji, Masuda, Ryuzo, Sasaki, Hiroyoshi, Konishi, Takashi, Tanimura   +6 more
openaire   +2 more sources

Approaches to Manipulate Ephrin-A:EphA Forward Signaling Pathway

Pharmaceuticals, 2020
Erythropoietin-producing hepatocellular carcinoma A (EphA) receptors and their ephrin-A ligands are key players of developmental events shaping the mature organism. Their expression is mostly restricted to stem cell niches in adults but is reactivated in
Sarah Baudet, Johann Bécret, Xavier Nicol   +2 more
doaj   +1 more source

Mechanism of haematotoxicity induced by phenylhydrazine: a review

Journal of Applied Pharmaceutical Research, 2019
This work was carried out to show the effects of phenylhydrazine (PHZ) induced anaemic condition. Anaemic condition is defined as reduction in red blood cells (RBC) than normal number of red blood cells. The anti-anaemic activity can be studied using the
B R Shwetha, H S Siddalingaprasad, Shivukumar Swamy, N C Nagalakshmi, M G Hariprasad   +4 more
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Erythropoietin receptor response circuits [PDF]

Current Opinion in Hematology, 2010
In 1985-1989, erythropoietin (EPO), its receptor (EPOR), and janus kinase 2 were cloned; established to be essential for definitive erythropoiesis; and initially intensely studied. Recently, new impetus, tools, and model systems have emerged to re-examine EPO/EPOR actions, and are addressed in this review.
Don M, Wojchowski, Pradeep, Sathyanarayana, Arvind, Dev   +2 more
openaire   +2 more sources

Immunohistochemical expression of erythropoietin and erythropoietin receptor in breast carcinoma [PDF]

Cancer, 2002
AbstractBACKGROUNDErythropoietin (Epo), induced by hypoxia, controls the survival, proliferation, and differentiation of Epo receptor (EpoR)‐bearing erythroid progenitors and plays a role in the protection of neurons from hypoxic damage. Hypoxia in malignant disease is associated with invasion, metastasis, resistance to therapy, and selection for cells
Geza, Acs, Paul J, Zhang, Timothy R, Rebbeck, Peter, Acs, Ajay, Verma   +4 more
openaire   +2 more sources

Erythropoietin: a new perspective in cardiovascular therapy

Monaldi Archives for Chest Disease, 2016
Erythropoietin is a hormone produced by the kidney, which regulates proliferation, differentiation and maturation of red cells. Recombinant human EPO (rH-EPO) is well known to correct anaemia in patients with chronic renal failure in terminal stage ...
Riccardo Raddino, Debora Robba, Giorgio Caretta, Ivano Bonadei, Melissa Teli, Gregoriana Zanini, Alberto Madureri, Enrico Vizzardi, Livio Dei Cas   +8 more
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Erythropoietin Protects the Kidney by Regulating the Effect of TNF-α in L-NAME-Induced Hypertensive Rats

Kidney & Blood Pressure Research, 2018
Background/Aims: Hypertension is the leading cause of death worldwide. Chronic high blood pressure induces inflammation. Tumor necrosis factor (TNF)-α plays a major role in inflammation and also depresses the synthesis of erythropoietin, which exerts ...
Mete Ozkurt, Kubilay Uzuner, Nilufer Erkasap, Gokhan Kus, Rumeysa Ozyurt, Onur Uysal, Ibrahim Akyazi, Ozden Kutlay   +7 more
doaj   +1 more source

von Hippel-Lindau disease-associated hemangioblastomas are derived from embryologic multipotent cells. [PDF]

PLoS Medicine, 2007
BACKGROUND: To determine the origin of the neoplastic cell in central nervous system (CNS) hemangioblastomas in von Hippel-Lindau disease (VHL) and its role in tumor formation and distribution, we characterized and differentiated neoplastic cells from ...
Deric M Park, Zhengping Zhuang, Ling Chen, Nicholas Szerlip, Irina Maric, Jie Li, Taesung Sohn, Stephanie H Kim, Irina A Lubensky, Alexander O Vortmeyer, Griffin P Rodgers, Edward H Oldfield, Russell R Lonser   +12 more
doaj   +1 more source

Targeted Delivery of Erythropoietin Hybridized with Magnetic Nanocarriers for the Treatment of Central Nervous System Injury: A Literature Review

International Journal of Nanomedicine, 2020
Chang Ho Hwang Department of Physical and Rehabilitation Medicine, Chungnam National University Sejong Hospital, Chungnam National University College of Medicine, Sejong, Republic of KoreaCorrespondence: Chang Ho HwangDepartment of Physical and ...
Hwang CH
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