Glycosylation of the murine erythropoietin receptor [PDF]
Murine erythropoietin‐responsive Rauscher Red 5‐1.5 cells were used to determine the contribution of glycosylation to the size and function of the erythropoietin receptor. The half life of the receptors was determined to be 4 h. The number of receptors was not significantly decreased in cells treated for 48 h with inhibitors of glycosylation ...
Mayeux, P. +3 more
openaire +4 more sources
EFFECT OF ERYTHROPOIETIN ON CYTOKINE PRODUCTION BY STEM CELLS [PDF]
Erythropoietin (EPO) is mainly used to stimulate erythropoiesis. Its cytoprotective effects upon other cells of the human body and animals were recently shown, in particular, anti-apoptotic effect was observed.
A. P. Lykov +6 more
doaj +2 more sources
Erythropoiesis, serum erythropoietin, and serum IGF-I in rats during accelerated growth [PDF]
In this study we have examined the correlation between activity of erythropoiesis and serum concentrations of erythropoietin and insulin-like growth factor I in male and female rats during accelerated growth (day 30-90).
Kurtz, Armin +3 more
core +1 more source
Oxygen-dependent expression of the erythropoietin gene in rat hepatocytes in vitro [PDF]
Since in juvenile rats the liver is the predominant site of erythropoietin (EPO) gene expression, we have used primary cultures of juvenile rat hepatocytes to establish and in vitro system for investigation of oxygen-dependent EPO formation.
Kurtz, Armin +11 more
core +1 more source
Second-generation non-hematopoietic erythropoietin-derived peptide for neuroprotection
Erythropoietin (EPO) is a well-known erythropoietic cytokine having a tissue-protective effect in various tissues against hypoxic stress, including the brain. Thus, its recombinants may function as neuroprotective compounds. However, despite considerable
Bongki Cho +6 more
doaj +1 more source
Oxygen-dependent erythropoietin production by the isolated perfused rat kidney [PDF]
In this study we have investigated the role of oxygen delivery and of classic second messengers on erythropoietin production by the isolated perfused rat kidney. We found that the rat kidney was capable of de novo synthesis of erythropoietin.
Scholz, Holger +4 more
core +1 more source
Evaluation of the stability of human erythropoietin in samples for radioimmunoassay [PDF]
Radioimmunoassays for erythropoietin are limited so far to a few specialized laboratories and this requires transport and storage of samples. We therefore tested the stability of immunoreactive erythropoietin in serum and plasma samples obtained from a ...
Kurtz, Armin +5 more
core +1 more source
Erythropoietin receptor and hematological disease [PDF]
This review will discuss evidence for the role of the erythropoietin (Epo) receptor in the development of erythrocytosis and other hematological disorders. The possible causative role of mutations of other genes in the pathogenesis of idiopathic erythrocytosis will be considered. Polycythemia vera (PV) is a myeloproliferative disorder that is caused by
McMullin, Mary Frances, Percy, M.J.
openaire +2 more sources
Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care [PDF]
Author can archive publisher's pdf. Free via Creative Commons: CC-BENCHTOBEDSIDE-2.0.
Thiemermann, C, Patel, NSA, Nandra, KK
core +1 more source
Possible erythropoietin pharmacotherapeutic targets on painful diabetic neuropathy in rats [PDF]
Erythropoietin is a renal cytokine involved in regulating hematopoiesis. Current evidence indicates that erythropoietin exerts pleiotropic effects in animal models.
SAMUEL SUAREZ-MENDEZ +1 more
doaj +1 more source

